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India responds aggressively to COVID-19

As the world is gripped with COVID-19 infection and fears of transmission, Southeast Asian nation India, being China’s neighbor and the second most populous nation (with 1.3 billion population) in the world, is not spared.

17 Mar 2020

New understanding of signaling molecule interleukin-2 can guide drug discovery efforts

The signaling molecule interleukin-2 (IL-2) has long been known to have powerful effects on the immune system, but efforts to harness it for therapeutic purposes have been hampered by serious side effects.

17 Mar 2020

TTP plc establishes new partnership to enable better clinical management of patients with atrial fibrillation

TTP plc, a leading independent technology and product development company, today announced it has established a partnership with NHS Highland and The University of the Highlands and Islands, to use clinical data interpretation and machine learning algorithms to predict which patients with atrial fibrillation are able to be successfully treated using electrical cardioversion.

17 Mar 2020

$Acid reflux drugs may lead to increased risk of fractures in children$

Acid reflux drugs may lead to increased risk of fractures in children

Proton pump inhibitors - a widely used class of drugs used to treat acid reflux and related symptoms - may lead to an increased risk of fractures in children and adolescents, reports a study in the Journal of Pediatric Gastroenterology and Nutrition.

17 Mar 2020

Uncovering the Achilles' heel of cancer cells to find effective cures

The key to effective cures for cancers is to find weak points of cancer cells that are not found in non-cancer cells.

17 Mar 2020

Researchers elucidate new mechanism for controlling DNA methylation in cells

Why normal cells turn into cancer cells One of the factors is deeply related to the failure of the cell differentiation mechanism called DNA methylation.

17 Mar 2020

Antioxidant treatment in acute ischemic stroke could delay onset of clinically overt dementia

Currently we are facing a dementia epidemic, with estimations showing that by 2050 approximately 131 million people will be affected.

17 Mar 2020

Study unravels molecular mechanism behind autoimmune and inflammatory diseases

A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis.

17 Mar 2020

Beijing Tide Pharmaceutical and Insilico Medicine announce cancer drug discovery collaboration

Beijing Tide Pharmaceutical Co., Ltd., a subsidiary of Sino Biopharmaceutical Limited, and Insilico Medicine, an artificial intelligence company developing end-to-end drug discovery pipelines, announced today that they are entering a collaboration, applying artificial intelligence technology to drug discovery, to jointly accelerate the process for multiple types of cancer treatment.

16 Mar 2020

Immunotherapy combination can shrink viral reservoir in HIV model

Stimulating immune cells with two cancer immunotherapies together can shrink the size of the viral "reservoir" in SIV-infected non-human primates treated with antiviral drugs, researchers have concluded.

16 Mar 2020

Researchers show possibility of blending two incompatible components in one nanofiber

Russian researchers from the Federal Research Clinical Center of Physical-Chemical Medicine, the Moscow Institute of Physics and Technology, and Lomonosov Moscow State University showed the possibility of blending two incompatible components -- a protein and a polymer -- in one electrospun fiber.

16 Mar 2020

Key antibiotic used for treating drug-resistant TB does not work as expected

Crick and Imperial researchers have found that a key antibiotic widely used to treat drug-resistant tuberculosis does not work as expected - a finding which could be used to develop new drugs.

16 Mar 2020

Anesthesia standards for coronavirus-infected patients requiring emergency surgery

Physicians describe the standardized procedure of surgical anesthesia for patients with COVID-19 infection requiring emergency surgery to minimize the risk of virus spread and reduce lung injury in a Letter to the Editor published in Surgical Infections, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

16 Mar 2020

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020