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Characterization of DNAm status of MMPs and TIMPs in atheromatous plaques

Oncotarget Volume 11, Issue 10 reported that the statistically associated Cp G sites were analyzed in blood samples from two separate atherothrombotic stroke cohorts, ischemic stroke-cohort 1: 37 atherothrombotic patients and 6 controls, ischemic stroke-cohort 2: 80 atherothrombotic patients and 184 controls.

13 Mar 2020

UC Riverside biochemist and Atomwise form new joint venture

Over the past few years, biochemist John Jefferson Perry at the University of California, Riverside, has collaborated on a number of projects with Atomwise Inc., a company that uses artificial intelligence, or AI, for drug discovery.

13 Mar 2020

Tooth-enamel protein discovered in the eyes of people with dry AMD

A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration, according to a study from researchers at the National Eye Institute.

13 Mar 2020

Patients prescribed opioids after dental extraction report higher levels of pain

The use of opioids to soothe the pain of a pulled tooth could be drastically reduced or eliminated altogether from dentistry, say University of Michigan researchers.

13 Mar 2020

Pediatric Infectious Disease Journal review: COVID-19 appears less severe in children

As outbreaks of COVID-19 disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue worldwide, there's reassuring evidence that children have fewer symptoms and less severe disease.

13 Mar 2020

Single-drug therapy can attack several cellular targets using different modes of action

Clinicians combat the drug resistances of some cancer types by using a combination of different drugs. To make this approach more effective, chemists have designed a chemical conjugate that can simultaneously attack several cellular targets using different modes of action.

13 Mar 2020

Triple therapies effective and safe in malaria

A new study describing the outcome of a clinical trial of two malaria treatment protocols involving the use of triple therapies based on artemisinin reports their high efficacy and low adverse effects.

12 Mar 2020

'Flattening the curve' - why is it important for coronavirus?

With the emergence of the novel coronavirus and the propagation of the infectious disease COVID-19 around the world, everyone is talking about 'flattening the curve'. But what does this mean, and why is it so important?

12 Mar 2020

What does COVID-19 do to the body?

The novel coronavirus SARS-CoV-2, also known as 2019-nCoV, is the virus that causes COVID-19, and that is spreading throughout the world is causing panic in almost all countries. With a death rate ranging from 1% to 2% in young patients but about 5%-8% in elderly and sick patients, it is capable of ravaging multiple organ systems in the human body.

12 Mar 2020

Weather modeling data helps predict potential spread and seasonality for COVID-19

Researchers at the University of Maryland School of Medicine's Institute of Human Virology (IHV), which is part of the Global Virus Network, predict that COVID-19 will follow a seasonal pattern similar to other respiratory viruses like seasonal flu.

12 Mar 2020

Aspergillus molds induce asthma by first attacking the lung's protective barrier

University of Wisconsin-Madison researchers have identified a new way that common Aspergillus molds can induce asthma, by first attacking the protective tissue barrier deep in the lungs.

12 Mar 2020

New nano strategy for 'trapping and zapping' antibiotic resistant genes

It's not enough to take antibiotic-resistant bacteria out of wastewater to eliminate the risks they pose to society. The bits they leave behind have to be destroyed as well.

12 Mar 2020

Innovative technique can create new type of biocompatible microparticles

Biomedical engineers at Duke University have devised a method for making small particles that are safe for living tissues that will allow them to create new shapes attractive for drug delivery, diagnostics and tissue engineering.

12 Mar 2020

Researchers uncover clues to how statins kill cancer cells

More than 35 million Americans take statin drugs daily to lower their blood cholesterol levels. Now, in experiments with human cells in the laboratory, researchers at Johns Hopkins Medicine have added to growing evidence that the ubiquitous drug may kill cancer cells and have uncovered clues to how they do it.

12 Mar 2020

Robots and AI deployed to fight against coronavirus

Robots and artificial intelligence are being deployed across the globe in the fight against the coronavirus pandemic.

12 Mar 2020

Tampons, pads and politics mesh in new push for access to menstrual supplies

Geoff Davis' gray Kia sedan is chock-full of tampons and maxi pads.

12 Mar 2020

Could rushing a coronavirus vaccine cause more harm?

Amid the coronavirus disease (COVID-19) pandemic that is rapidly spreading worldwide, scientists are becoming more concerned that rushing vaccine production to prevent the infection may do more harm than good to patients.

12 Mar 2020

Potential breakthrough in cancer immunotherapy with gasdermin E

A new study published in the journal Nature in March 2020 reports the discovery of a new approach to cancer immunotherapy, which could be useful in many more cancers than at present.

11 Mar 2020

Virtual reality becomes a drug design tool

A new study published in March 2020 in the journal PLOS ONE shows the use of virtual reality (VR) as a powerful tool to create next-generation therapeutics. The focus is on the ability of VR to simulate the way commonly used drugs act on the cells at the molecular level, which enables innovation to improve the mechanism of action or to use alternate mechanisms.

11 Mar 2020

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

In a new retrospective study, researchers found that the use of immunosuppressive therapy does not increase the occurrence or recurrence of vulvar or vaginal cancer in women with inflammatory bowel disease (IBD).

11 Mar 2020