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Researchers identify a biomarker in platelets that tracks the extent of depression

Researchers are one step closer to developing a blood test that provides a simple biochemical hallmark for depression and reveals the efficacy of drug therapy in individual patients.

3 Jan 2022

Humanized antibody shows strong neutralization ability against SARS-CoV-2 Delta variant

Researchers combine SARS-CoV-2 spike vaccination with single-cell B-cell receptor sequencing technology to discover neutralizing antibody candidates.

3 Jan 2022

Minimal nAb titers against Omicron in the elderly after 3rd dose

Researchers measured titers of cross-protective neutralizing antibodies against SARS-CoV-2 after they had received a third booster dose.

3 Jan 2022

Alzheimer’s disease risk genes disturb the brain protective mechanism

The brain has a natural protective mechanism against Alzheimer's disease, and researchers at Baylor College of Medicine, Texas Children's Hospital and collaborating institutions have discovered that gene variants associated with risk of developing the disease disturb the protective mechanism in ways that can lead to neurodegeneration.

3 Jan 2022

Genomic variant may help predict which patients will experience chemotherapy-induced cardiotoxicity

A team of investigators have discovered a genomic variant that may help clinicians predict which patients will experience cardiotoxicity from a widely used chemotherapy drug, according to a Northwestern Medicine study published in Circulation.

3 Jan 2022

Researchers discover how the sponginess of stem cell nuclei controls cell differentiation

Researchers from Tokyo Metropolitan University have discovered how the sponginess and stickiness of stem cell nuclei controls how they "differentiate" into specialized cells.

3 Jan 2022

Less severe clinical consequences of infection with SARS-CoV-2 Omicron variant

New evidence implies that the Omicron variant may cause a less severe and/or faster recovery from clinical COVID-19 disease.

31 Dec 2021

Omicron infection induces cross-reactive immune responses

New research revealed that vaccine-breakthrough infections might elicit cross-reactive bNAbs against all variants of concern.

31 Dec 2021

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

A new study used in silico approaches for designing a next-generation CD40-targeting vaccine, CD40.

31 Dec 2021

New study shows how cells eat the things around them

A new study shows how cell membranes curve to create the "mouths" that allow the cells to consume things that surround them.

31 Dec 2021

Microgravity likely to contribute to life-saving stem cell advances on Earth

The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space. Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells.

30 Dec 2021

Researchers warn about the dangers of vitamin B12 deficiency in people following plant-based diets

In the run up to Veganuary leading researchers are warning of the dangers of a quiet epidemic of vitamin B12deficiencyin people who follow increasingly popular plant-based diets.

30 Dec 2021

A reliable assessment of COVID-19 vaccine protection duration

Researchers from the University of North Carolina, University of Washington, and the US Food and Drug Administration propose fitting a Cox model with two time indexes, the event times measured from the start of the study in calendar time and the log hazard for the vaccine effect.

30 Dec 2021

How much do mutations reduce vaccine effectiveness in the Omicron variant?

In new research, scientists from Adaptive Biotechnologies have been investigating the impact of spike protein mutations on vaccine efficiency for the Omicron variant. The study is currently available on the medRxiv* preprint server while awaiting peer review.

30 Dec 2021

Vaccine-induced T-cells vs. Omicron well preserved compared with all variants

A team of international scientists has recently revealed that T cell responses induced by coronavirus disease 2019 (COVID-19) vaccines are able to cross-recognize different variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The study is currently available on the bioRxiv* preprint server.

30 Dec 2021

SARS-CoV-2 infection and immunity in pregnancy and fetal development

A review conducted by a team of researchers from the Icahn School of Medicine at Mount Sinai, the University of Colorado, and Active Motif, Incorporated compiles information on SARS-CoV-2 virology, in utero transmission from infected pregnant mothers to fetuses, new findings on possible methods of SARS-CoV-2 cellular trafficking through exosomes, and the transcriptomic effects of SARS-CoV-2 infection, in order to inform future studies aimed at a better understanding of COVID-19 and the development of therapeutic solutions against SARS-CoV-2.

30 Dec 2021

The use of monoclonal antibodies against infectious pathogens

Joshua Tan of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health wrote a review article in the journal DNA and Cell Biology about the role of monoclonal antibodies and briefly described a study on bispecific antibodies that neutralize SARS-CoV-2.

30 Dec 2021

B Cell News and Research

Researchers identify a biomarker in platelets that tracks the extent of depression

Humanized antibody shows strong neutralization ability against SARS-CoV-2 Delta variant

Minimal nAb titers against Omicron in the elderly after 3rd dose

Alzheimer’s disease risk genes disturb the brain protective mechanism

Genomic variant may help predict which patients will experience chemotherapy-induced cardiotoxicity

Researchers discover how the sponginess of stem cell nuclei controls cell differentiation

Less severe clinical consequences of infection with SARS-CoV-2 Omicron variant

Omicron infection induces cross-reactive immune responses

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

New study shows how cells eat the things around them

Microgravity likely to contribute to life-saving stem cell advances on Earth

Researchers warn about the dangers of vitamin B12 deficiency in people following plant-based diets

A reliable assessment of COVID-19 vaccine protection duration

How much do mutations reduce vaccine effectiveness in the Omicron variant?

Vaccine-induced T-cells vs. Omicron well preserved compared with all variants

SARS-CoV-2 infection and immunity in pregnancy and fetal development

The use of monoclonal antibodies against infectious pathogens

P323L mutations in SARS-CoV-2 are highly predictive of the emergence of new variants

Reviewing myocarditis and pericarditis in immunosuppressed individuals following COVID-19 mRNA vaccination

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Using single B cell screening to boost antibody discovery eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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