immunity News and Research

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Single dengue vaccine dose shows mixed results: Protection hinges on prior exposure

Study investigates the protective effects of a single CYD-TDV vaccine dose against dengue virus in Filipino children, revealing that while the vaccine does not protect children with no or one prior dengue infection, it significantly reduces infection risk in those with two or more prior infections.

26 Mar 2024

GPT-4 shows expert-level accuracy in annotating cell types

GPT-4 can accurately interpret types of cells important for the analysis of single-cell RNA sequencing -- a sequencing process fundamental to interpreting cell types – with high consistency to that of time-consuming manual annotation by human experts of gene information, according to a study at Columbia University Mailman School of Public Health.

26 Mar 2024

Researchers identify viable vaccine targets for hepatitis C infections

By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.

26 Mar 2024

Project PROTECTS launches to track acute respiratory infections across the United States

The City University of New York (CUNY) Institute for Implementation Science in Population Health (ISPH) and the CUNY Graduate School of Public Health and Health Policy (CUNY SPH), in collaboration with Pfizer, are initiating a critical two-year prospective epidemiologic study in the spring of 2024 to track acute respiratory infections across the United States.

22 Mar 2024

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

Astrocyte immune memory in multiple sclerosis pathology revealed

Immunological memory - the ability to respond to a previously encountered antigen, or foreign substance, with greater speed and intensity on re-exposure is a hallmark of adaptive immunity.

20 Mar 2024

Immune cell protein identified as potential target for rare liver cancer treatment

Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein.

20 Mar 2024

Ownership-based text messages boost COVID booster uptake

New research published in Nature Human Behavior suggests that text nudges encouraging people to get the COVID-19 vaccine, which had proven effective in prior real-world field tests, are also effective at prompting people to get a booster.

18 Mar 2024

Study reveals why COVID-19 antibodies fade quickly

Researchers at the Institute of Human Virology (IHV) at the University of Maryland School of Medicine published a new study in the Journal of Infectious Diseases investigating the antibody response following SARS-CoV-2 infection.

18 Mar 2024

Researchers study newborn piglets to better understand the progression of influenza

Although prevention and treatment strategies are available for influenza, they are not sufficient for vulnerable populations such as young children and newborns.

18 Mar 2024

Punitive prenatal drug laws lead to negative health outcomes

Contrary to some claims, laws that criminalize or otherwise punish drug use during pregnancy are more likely to worsen rather than improve health outcomes, according to a paper by researchers at Columbia University Mailman School of Public Health.

18 Mar 2024

Middle-aged adults in the U.S. experience higher levels of loneliness than European counterparts

Middle-aged adults in the U.S. tend to report significantly higher levels of loneliness than their European counterparts, possibly due in part to weaker family ties and greater income inequality, according to research published by the American Psychological Association.

18 Mar 2024

Rising antifungal resistance heightens concerns over invasive fungal infections

A global wave of infections caused by fungi growing drug-resistant has the medical community issuing precautions on how to protect yourself.

18 Mar 2024

New compounds show potential to mimic benefits of exercise

Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise.

18 Mar 2024

Synthetic mucins shed light on cancer biology and tumor formation

During cold and flu season, excess mucus is a common, unpleasant symptom of illness, but the slippery substance is essential to human health.

18 Mar 2024

Scientists aim to understand why T cells do not sustain energy in tumors

T cells are often called "assassins" or "killers" because they can orchestrate and carry out missions to hunt down bacteria, viruses, and cancer cells throughout the body.

15 Mar 2024

Eating fatty food before surgery may affect memory-related cognitive function in older adults

Eating fatty food in the days leading up to surgery may prompt a heightened inflammatory response in the brain that interferes for weeks with memory-related cognitive function in older adults – and, new research in animals suggests, even in young adults.

15 Mar 2024

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

Researchers identify T-cell subsets as effective therapeutic target for preventing transplant rejection

Houston Methodist researchers identified a troublesome subset of T-cells in transplant recipients that may be a more effective therapeutic target for preventing transplant rejection in patients.

14 Mar 2024

Study highlights impact of government vaccine recommendations and direct-to-consumer pharmaceutical advertising

A new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommendations to drugmakers, as well as potential benefits of advertising pharmaceuticals directly to consumers - a practice that is banned in every country apart from the United States and New Zealand.

13 Mar 2024

immunity News and Research

Single dengue vaccine dose shows mixed results: Protection hinges on prior exposure

GPT-4 shows expert-level accuracy in annotating cell types

Researchers identify viable vaccine targets for hepatitis C infections

Project PROTECTS launches to track acute respiratory infections across the United States

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

Astrocyte immune memory in multiple sclerosis pathology revealed

Immune cell protein identified as potential target for rare liver cancer treatment

Ownership-based text messages boost COVID booster uptake

Study reveals why COVID-19 antibodies fade quickly

Researchers study newborn piglets to better understand the progression of influenza

Punitive prenatal drug laws lead to negative health outcomes

Middle-aged adults in the U.S. experience higher levels of loneliness than European counterparts

Rising antifungal resistance heightens concerns over invasive fungal infections

New compounds show potential to mimic benefits of exercise

Synthetic mucins shed light on cancer biology and tumor formation

Scientists aim to understand why T cells do not sustain energy in tumors

Eating fatty food before surgery may affect memory-related cognitive function in older adults

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Researchers identify T-cell subsets as effective therapeutic target for preventing transplant rejection

Study highlights impact of government vaccine recommendations and direct-to-consumer pharmaceutical advertising

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

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