Immune System News and Research

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People with celiac disease have reactions to non-gluten wheat proteins

Although gluten-free foods are trendy among the health-conscious, they are necessary for those with celiac disease. But gluten, the primary trigger for health problems in these patients, may not be the only culprit. Scientists are reporting in ACS' Journal of Proteome Research that people with the disease also have reactions to non-gluten wheat proteins. The results could help scientists better understand how the disease works and could have implications for how to treat it.

6 Nov 2014

Effects of unhealthy lifestyle persist even after atherosclerosis treatment

Almost everyone knows that improving your eating habits will most likely improve your health. What most people may not know, however, is that the effects of poor eating habits persist long after dietary habits are improved. In a new report appearing in the November 2014 issue of the Journal of Leukocyte Biology, scientists use mice to show that even after successful treatment of atherosclerosis (including lowering of blood cholesterol and a change in dietary habits) the effects of an unhealthy lifestyle still affect the way the immune system functions.

6 Nov 2014

Penn researchers show that 23% of patients who survive septic shock return to hospital within 30 days

A diagnosis of septic shock was once a near death sentence. At best, survivors suffered a substantially reduced quality of life.

6 Nov 2014

ProstaCaid dietary supplement supports prostate health

A recent presentation at an international cancer research conference in Greece reviewed the body of data on ProstaCaid, a dietary supplement compound for prostate health. A number of published studies demonstrate the formula's effects in supporting prostate health against specific prostate cancer cell lines and prostate urinary symptoms.

5 Nov 2014

Study suggests possible link between body fat and risk of immunotherapy toxicity

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found.

4 Nov 2014

Researchers develop new test to identify drugs that could work against Lyme disease

Researchers from the Johns Hopkins Bloomberg School of Public Health have developed a test they say will allow them to test thousands of FDA-approved drugs to see if they will work against the bacteria that causes tick-borne Lyme disease.

4 Nov 2014

Study reports IL-37's activity in the adaptive immune system

A University of Colorado Cancer Center study published in this month's Proceedings of the National Academy of Sciences describes the activity of a recently discovered communication molecule of the body's immune system, Interleukin 37 or IL-37. It has been known to limit inflammation and the current study reports its activity in the adaptive immune system: IL-37 inhibits the ability of the immune system to recognize and target new antigens.

4 Nov 2014

Rigel Pharmaceuticals reports net loss of $20.9 million for third quarter of 2014

Rigel Pharmaceuticals, Inc. today reported financial results for the third quarter and nine months ended September 30, 2014.

4 Nov 2014

Scientists obtain first structure of the immature form of HIV

Scientists at the European Molecular Biology Laboratory in Heidelberg, Germany and collaborators from Heidelberg University, in the joint Molecular Medicine Partnership Unit, have obtained the first structure of the immature form of HIV at a high enough resolution to pinpoint exactly where each building block sits in the virus.

4 Nov 2014

UC Davis researchers link increased body fat and lethal drug reactions in mice

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. The findings, published online today in The Journal of Experimental Medicine, suggest a possible link between body fat and the risk of toxicity from some types of immunotherapy.

3 Nov 2014

New research sheds light on future efforts to eradicate HIV from the body in human patients

Where does HIV hide? Antiretroviral drugs can usually control the virus, but can't completely eliminate it. So any strategy to eradicate HIV from the body has to take into account not only the main group of immune cells the virus targets, called CD4 or helper T cells, but other infected cells as well.

3 Nov 2014

FDA approves Fluzone High-Dose vaccine sBLA to include efficacy data in Prescribing Information

Sanofi Pasteur, the vaccines division of Sanofi, today announced that the U.S. Food and Drug Administration has approved the supplemental biologics license application (sBLA) for Fluzone High-Dose (Influenza Vaccine) to include efficacy data in the Prescribing Information.

3 Nov 2014

Epicure project: an interview with Frédéric Cren

Epicure is a project led by Inventiva and Institut Curie that aims to deliver pre-clinical candidates on two novel epigenetic targets that have been selected due to their potential to activate immune responses against cancer cells. In addition one of these two targets has potential in respiratory indications such as asthma or COPD.

3 Nov 2014

Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

An antibody abundant in mice and previously thought to offer poor assistance in fighting against infection may actually play a key role in keeping immune responses in check and preventing more serious self-inflicted forms of kidney disease, researchers say.

3 Nov 2014

Researchers develop mouse model to improve basic research on Ebola treatments, vaccines

Researchers at the University of North Carolina at Chapel Hill and colleagues have developed the first genetic strain of mice that can be infected with Ebola and display symptoms similar to those that humans experience.

31 Oct 2014

Study identifies new targets for developing novel treatment for alcohol dependence

Bacteria in the gastrointestinal tract fulfill many vital functions and are critical for digestion. Yet, these same bacteria can induce strong inflammatory responses by the immune system if they penetrate the gut and enter the bloodstream.

31 Oct 2014

Researchers develop new technique to create cellular scaffolding for tissue engineering

Researchers at the University of Washington have developed a way to use sound to create cellular scaffolding for tissue engineering, a unique approach that could help overcome one of regenerative medicine's significant obstacles.

31 Oct 2014

New research shows link between perinatal exposure to BPA and risk of food intolerance in later life

If it seems like more people are allergic to, or intolerant of, more and different kinds of foods than ever before, there might be a reason why. A new research published in November 2014 issue of The FASEB Journal, scientists show, for the first time, that there is a link between perinatal exposure to Bisphenol A (BPA) at low doses and the risk to develop food intolerance in later life.

31 Oct 2014

BRI receives JDRF grant to explore why people with type 1 diabetes continue to produce insulin

Scientists at Benaroya Research Institute at Virginia Mason are studying a critical question in type 1 diabetes: Why do some people who get type 1 diabetes continue to produce small amounts of insulin over time while others stop? Researchers have found at the time of diagnosis with type 1 diabetes that many people continue to produce small amounts of insulin.

31 Oct 2014

Insufficient Th1 polarisation blocks RCC vaccine efficacy

A lack of a clinical response to an allogenic gene-modified renal cell cancer vaccine may be due to insufficient type 1 T-helper cell polarisation, show results of a gene expression profiling study.

30 Oct 2014

Immune System News and Research

People with celiac disease have reactions to non-gluten wheat proteins

Effects of unhealthy lifestyle persist even after atherosclerosis treatment

Penn researchers show that 23% of patients who survive septic shock return to hospital within 30 days

ProstaCaid dietary supplement supports prostate health

Study suggests possible link between body fat and risk of immunotherapy toxicity

Researchers develop new test to identify drugs that could work against Lyme disease

Study reports IL-37's activity in the adaptive immune system

Rigel Pharmaceuticals reports net loss of $20.9 million for third quarter of 2014

Scientists obtain first structure of the immature form of HIV

UC Davis researchers link increased body fat and lethal drug reactions in mice

New research sheds light on future efforts to eradicate HIV from the body in human patients

FDA approves Fluzone High-Dose vaccine sBLA to include efficacy data in Prescribing Information

Epicure project: an interview with Frédéric Cren

Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

Researchers develop mouse model to improve basic research on Ebola treatments, vaccines

Study identifies new targets for developing novel treatment for alcohol dependence

Researchers develop new technique to create cellular scaffolding for tissue engineering

New research shows link between perinatal exposure to BPA and risk of food intolerance in later life

BRI receives JDRF grant to explore why people with type 1 diabetes continue to produce insulin

Insufficient Th1 polarisation blocks RCC vaccine efficacy

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