Immune System News and Research

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Penn Medicine, Wistar Institute awarded NCI grants for four new melanoma research projects

Penn Medicine and The Wistar Institute have been awarded a prestigious $12.1 million SPORE grant from the National Cancer Institute. The five-year Specialized Programs of Research Excellence, or SPORE, grant will fund four new melanoma research projects that aim to translate fundamental laboratory discoveries into new therapeutics to treat melanoma and other skin cancers.

18 Sep 2014

Common type of hospital-associated infections can be prevented with vaccine

The most common type of hospital-associated infection may be preventable with a vaccine, new research in mice suggests.

18 Sep 2014

Immune begins bertilimumab Phase II clinical trial for treatment of ulcerative colitis

Immune Pharmaceuticals Inc. announces today that it has initiated the screening of patients for a Phase II proof of concept clinical trial exploring the safety and efficacy of bertilimumab in the treatment of ulcerative colitis (UC).

18 Sep 2014

Parous women have higher chance of developing estrogen receptor-negative breast cancer

Women who have had children (parous women) appear to have an increased risk of developing estrogen receptor-negative breast cancer, the subtype that carries a higher mortality rate and is more common in women of African ancestry.

17 Sep 2014

Curie-Cancer, Inventiva launch Epicure project that aims to develop epigenetic targets for cancer

Curie-Cancer, the body responsible for developing Institut Curie’s industry partnership activities, and Inventiva, a drug discovery company that focuses on therapeutic approaches involving transcription factors and epigenetic targets, today announce the launch of the Epicure project, which has just received financial backing from France’s national research agency, the ANR [Agence Nationale pour la Recherche].

17 Sep 2014

MSU researchers show how bacterial immune systems fight off viruses

When this week's print issue of the journal Science comes out, a collective cheer will go up from New Mexico, Montana and even the Netherlands, thanks to the type of collaborative effort that is more and more the norm in these connected times. Yes, the research was brilliant, and if we're lucky, it will produce innovations in biology, medicine, biotechnology and agriculture. It could save lives, and it happened because this scientist talked with that one, that one knew another one, and brilliant minds overcame geographic distance to advance human understanding.

16 Sep 2014

Leaky intestines may cripple bacteria-fighting immune cells in patients with CVID

Leaky intestines may cripple bacteria-fighting immune cells in patients with a rare hereditary disease, according to a study by researchers in Lausanne, Switzerland. The study, published in The Journal of Experimental Medicine, may explain why these patients suffer from recurrent bacterial infections.

16 Sep 2014

T-bet protein fights off hepatitis infections

A single protein may tip the balance between ridding the body of a dangerous virus and enduring life-long chronic infection, according to a report appearing in The Journal of Experimental Medicine.

16 Sep 2014

Blocking bacteria's access to iron: an interview with Dr. Laxminarayana Devireddy

Iron is a key nutrient for nearly all living organisms, including bacteria. Iron is a cofactor for many enzymes necessary for basic metabolic reactions such as DNA synthesis and electron transport. Iron serves as the conduit for the electron transport chain that generates the energy necessary to drive the bacterial cell.

16 Sep 2014

Patients with particular genetic variation more prone to drug-induced pancreatitis

Doctors have discovered that patients with a particular genetic variation are four times more likely to develop pancreatitis if they are prescribed a widely used group of drugs.

16 Sep 2014

GILZ protein key to preventing bone loss, researchers report

A small protein named GILZ appears to protect against the bone loss that often accompanies arthritis and its treatment, researchers report.

15 Sep 2014

Researchers report that dendritic cells can affect psoriasis

Different types of dendritic cells in human skin have assorted functions in the early and more advanced stages of psoriasis report researchers in the journal EMBO Molecular Medicine.

15 Sep 2014

UC Irvine study sheds light on cognitive losses

Brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences, according to UC Irvine neuroscientists Jennifer Czerniawski and John Guzowski.

15 Sep 2014

Human stem cells can be reset to their native undifferentiated state

Scientists at the Babraham Institute, in collaboration with colleagues at the Cambridge Stem Cell Institute and the European Bioinformatics Institute, have made a breakthrough in stem cell research. Their paper, published today in Cell, describes how human stem cells can be reverted back to non-specialised cells.

11 Sep 2014

Loyola announces opening of new acupuncture clinic for patients with pelvic health disorders

Loyola University Health System will open an acupuncture clinic for men and women with pelvic health disorders this fall. The clinic will use acupuncture to treat patients with common conditions such as pelvic pain, nausea from pelvic surgery, interstitial cystitis, painful bladder syndrome, postoperative pain, prostatitis and overactive bladder.

11 Sep 2014

Cancer Research UK, CRT partner with Asterias to trail novel immunotherapy treatment for lung cancer

CANCER RESEARCH UK and Cancer Research Technology , the charity's development and commercialisation arm, have reached an agreement with Asterias Biotherapeutics, Inc., a biotechnology company in the emerging field of regenerative medicine, to take forward Asterias' novel immunotherapy treatment AST-VAC2 into clinical trials in subjects with non-small cell lung cancer.

11 Sep 2014

Pollution in many cities threatens brain development in children

Pollution in many cities threatens the brain development in children. Findings by University of Montana Professor Dr. Lilian Calder-n-Garcidue-as, MA, MD, Ph.D., and her team of researchers reveal that children living in megacities are at increased risk for brain inflammation and neurodegenerative changes, including Alzheimer's or Parkinson's disease.

11 Sep 2014

Immune System News and Research

Penn Medicine, Wistar Institute awarded NCI grants for four new melanoma research projects

Common type of hospital-associated infections can be prevented with vaccine

Immune begins bertilimumab Phase II clinical trial for treatment of ulcerative colitis

Parous women have higher chance of developing estrogen receptor-negative breast cancer

Curie-Cancer, Inventiva launch Epicure project that aims to develop epigenetic targets for cancer

MSU researchers show how bacterial immune systems fight off viruses

Leaky intestines may cripple bacteria-fighting immune cells in patients with CVID

T-bet protein fights off hepatitis infections

Blocking bacteria's access to iron: an interview with Dr. Laxminarayana Devireddy

Patients with particular genetic variation more prone to drug-induced pancreatitis

GILZ protein key to preventing bone loss, researchers report

Researchers report that dendritic cells can affect psoriasis

UC Irvine study sheds light on cognitive losses

Human stem cells can be reset to their native undifferentiated state

Loyola announces opening of new acupuncture clinic for patients with pelvic health disorders

Cancer Research UK, CRT partner with Asterias to trail novel immunotherapy treatment for lung cancer

Pollution in many cities threatens brain development in children

Beta-O2 receives grant from JDRF to study ßAir bio-artificial pancreas for treatment of T1D

Research sheds light on how collagen grows and helps form diverse set of structures in body

Relationship between stress hormones and immune function across different stages in life

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