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Apremilast drug shows promise for Behcet's ulcers

Apremilast, an orally available small molecule modulating several inflammatory pathways, which is pending approval by the United States Food and Drug Administration, is showing promise in the treatment of mouth and genital ulcers in people with Behcet's syndrome, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in San Diego.

28 Oct 2013

Study shows low uptake of HPV vaccination among patients with autoimmune diseases

The number of children and young adults with autoimmune diseases receiving the HPV vaccination is profoundly low despite studies showing the vaccine to be safe and effective, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego. Given the increased incidence of HPV in people with autoimmune diseases, this research suggests that increased public health efforts are needed.

28 Oct 2013

Patellofemoral knee brace can improve pain, bone marrow lesions in knee osteoarthritis patients

Use of a patellofemoral knee brace can improve pain symptoms and bone marrow lesions in patients with a type of osteoarthritis of the knee, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

COPD telemonitoring ‘costly and ineffective’

Results of a UK-based study indicate that telemonitoring adds little benefit to the self-management of chronic obstructive pulmonary disease.

25 Oct 2013

Scientists develop new drug to treat obstructive airway diseases

Scientists have developed a new drug (RPL554) that could treat obstructive airway diseases such as asthma and chronic obstructive pulmonary disease in two ways at once, according to new research published in The Lancet Respiratory Medicine.

25 Oct 2013

Participation in CARE for Teachers program reduces stress, improves teachers' well-being

Teacher well-being, efficacy, burnout-related stress, time-related stress and mindfulness significantly improve when teachers participate in the CARE (Cultivating Awareness and Resilience in Education) for Teachers program, according to Penn State researchers.

25 Oct 2013

Hands-free ultrasound device with clot-busting drug safe for ischemic stroke patients

A study led by researchers at The University of Texas Health Science Center at Houston (UTHealth) showed that a hands-free ultrasound device combined with a clot-busting drug was safe for ischemic stroke patients.

25 Oct 2013

Merck provides overview of clinical trial program for HPV vaccine V503

Merck, known as MSD outside the United States and Canada, today provided an overview of the clinical trial program for V503, the company's investigational 9-valent human papillomavirus vaccine, to the Advisory Committee on Immunization Practices in the United States.

25 Oct 2013

Researchers develop new interactive software game to help children with peanut allergies

Elizabeth McQuaid, Ph.D., a staff psychologist from the Bradley Hasbro Children's Research Center, is leading a research team testing a new interactive software game developed to help children with peanut allergies better manage allergy symptoms, social situations and proper food avoidance.

24 Oct 2013

Researchers improve cytostatic therapy for children with chronic immune deficiency disorder

Researchers at Karolinska Institutet in Sweden, and colleagues at University Children's Hospital Z-rich in Switzerland have managed to improve cytostatic therapy for children with the chronic immune deficiency disorder granulomatous disease prior to stem cell transplantation.

24 Oct 2013

HIV testing more effective than brief patient-centered counseling in preventing AIDS

For decades, people seeking an HIV test have been counseled on realistic and achievable steps they could take to avoid infection. But a national study led by Miller School investigators has determined that, given the rapid HIV tests available today, the resources devoted to pre-test counseling would be better spent on universal testing that could detect more HIV cases earlier, and link newly infected people to the treatment that could halt the spread of the virus.

24 Oct 2013

Cleveland Biolabs Subsidiary Awarded $4.6M Russian Contract

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23 Oct 2013

Scientists from University of Salzburg, Sandoz Pharmaceuticals and Thermo Fisher Scientific collaborate to advance protein-based pharmaceutical development

The Christian Doppler Laboratory for Biosimilar Characterization is now open at the Paris-Lodron University of Salzburg, and scientists there have commenced developing new methods for characterizing proteins to be used in biopharmaceuticals.

23 Oct 2013

New PARP inhibitor shows early responses in patients with advanced BRCA-related cancers

An investigational new PARP inhibitor, BMN 673, is showing early responses in patients with heavily pretreated, advanced, BRCA-related cancers of the breast and ovary, according to phase I clinical trial results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

23 Oct 2013

Angiochem presents results of Phase 2 study with ANG1005 in breast cancer patients with brain metastases

Angiochem, a clinical stage biotechnology company developing drugs that are uniquely capable of crossing the blood-brain barrier (BBB), announced that the complete analysis results of a Phase 2 clinical study with ANG1005, a novel paclitaxel-peptide drug conjugate, in breast cancer patients with brain metastasis were presented today at the 2013 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference.

23 Oct 2013

Influenza vaccination linked with reduced risk of adverse cardiovascular events

Receiving an influenza vaccination was associated with a lower risk of major adverse cardiovascular events such as heart failure or hospitalization for heart attack, with the greatest treatment effect seen among patients with recent acute coronary syndrome (ACS; such as heart attack or unstable angina), according to a meta-analysis published in the October 23/30 issue of JAMA.

23 Oct 2013

CSI receives PMA approval to market Diamondback 360 Coronary Orbital Atherectomy System

Cardiovascular Systems, Inc., today announced that it has received PMA approval from the U.S. Food and Drug Administration to market its Diamondback 360® Coronary Orbital Atherectomy System (OAS) as a treatment for severely calcified coronary arteries.

22 Oct 2013

AstraZeneca begins selumetinib Phase 3 clinical trial in NSCLC patients

AstraZeneca today announced the first patient randomized in a Phase 3 clinical trial for selumetinib, an oral, potent, selective MEK inhibitor, being investigated as second-line therapy in patients with advanced or metastatic non-small-cell lung cancer whose tumors are KRAS mutation-positive.

22 Oct 2013

COPD treatments: an interview with Professor Price, University of Aberdeen

The first thing is that we can’t cure COPD. The problem we have with COPD is that the process itself is not treatable, certainly not once it gets to the extent that it’s advanced.

22 Oct 2013

Psychotherapy: New treatment choice for anorexia nervosa

A large-scale study has now shown that adult women with anorexia whose disorder is not too severe can be treated successfully on an out-patient basis. Even after conclusion of therapy, they continue to make significant weight gains.

22 Oct 2013

Efficacy News and Research

Apremilast drug shows promise for Behcet's ulcers

Study shows low uptake of HPV vaccination among patients with autoimmune diseases

Patellofemoral knee brace can improve pain, bone marrow lesions in knee osteoarthritis patients

COPD telemonitoring ‘costly and ineffective’

Scientists develop new drug to treat obstructive airway diseases

Participation in CARE for Teachers program reduces stress, improves teachers' well-being

Hands-free ultrasound device with clot-busting drug safe for ischemic stroke patients

Merck provides overview of clinical trial program for HPV vaccine V503

Researchers develop new interactive software game to help children with peanut allergies

Researchers improve cytostatic therapy for children with chronic immune deficiency disorder

HIV testing more effective than brief patient-centered counseling in preventing AIDS

Cleveland Biolabs Subsidiary Awarded $4.6M Russian Contract

Scientists from University of Salzburg, Sandoz Pharmaceuticals and Thermo Fisher Scientific collaborate to advance protein-based pharmaceutical development

New PARP inhibitor shows early responses in patients with advanced BRCA-related cancers

Angiochem presents results of Phase 2 study with ANG1005 in breast cancer patients with brain metastases

Influenza vaccination linked with reduced risk of adverse cardiovascular events

CSI receives PMA approval to market Diamondback 360 Coronary Orbital Atherectomy System

AstraZeneca begins selumetinib Phase 3 clinical trial in NSCLC patients

COPD treatments: an interview with Professor Price, University of Aberdeen

Psychotherapy: New treatment choice for anorexia nervosa

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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