Abdominal Pain News and Research

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Abdominal pain is traditionally described by its chronicity (acute or chronic), its progression over time, its nature (sharp, dull, colicky), its distribution (by various methods, such as abdominal quadrant (left upper quadrant, left lower quadrant, right upper quadrant, right lower quadrant) or other methods that divide the abdomen into nine sections), and by characterization of the factors that make it worse, or alleviate it.

Quabodepistat combo shows promise for safer, faster tuberculosis treatment

Study highlights the safety and early bactericidal activity of quabodepistat when combined with delamanid, bedaquiline, or both, offering potential for shorter and more tolerable tuberculosis treatment regimens.

1 Dec 2024

New oral peptide therapy offers hope for chronic abdominal pain

A research team at the University of Vienna, led by medicinal chemist Markus Muttenthaler, has developed a new class of oral peptide therapeutic leads for treating chronic abdominal pain.

22 Nov 2024

New atlas maps 1.6 million human gut cells in unprecedented detail

The most comprehensive cell map of the human gut to date has been created by combining spatial and single-cell data from 1.6 million cells.

21 Nov 2024

Diabetes drugs cut asthma attacks by up to 70%, reshaping treatment options

Metformin and GLP-1 receptor agonists significantly reduce asthma attacks in patients with type 2 diabetes, offering potential new treatments for asthma.

19 Nov 2024

New oral painkiller developed for chronic abdominal pain

University of Queensland researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin that drives childbirth contractions.

18 Nov 2024

Study supports very early abortion for women seeking termination

Clinics and hospitals currently defer medication abortion until ultrasound confirms a pregnancy inside the uterus.

6 Nov 2024

Study highlights emergency department utilization among cancer patients in Ontario

About 1 in 3 patients diagnosed with cancer in Ontario visited an emergency department (ED) in the 90 days before diagnosis, found a new study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.240952.

4 Nov 2024

Lead exposure still poses health risks for millions worldwide, study finds

Addressing lead poisoning is vital for public health, as it contributes to cognitive decline and cardiovascular issues, especially in vulnerable populations.

4 Nov 2024

Alimetry secures $18 million to advance wearable gut health monitoring

Alimetry has raised an oversubscribed US $18m A2 financing round to commercialize its wearable gut health monitoring device, capitalizing on increased adoption by a growing cohort of US hospitals.

4 Nov 2024

Acupuncture shows promise in alleviating symptoms of chronic irritable bowel syndrome

A recent randomized controlled trial has shed light on the efficacy of acupuncture as a treatment for refractory irritable bowel syndrome (IBS), a chronic gastrointestinal disorder that significantly impacts quality of life and often resists conventional treatment.

1 Nov 2024

Ipsen's elafibranor recommended for use in patients with rare liver disease

Ipsen announced today that the National Institute for Health and Care Excellence (NICE) has recommended elafibranor 80mg tablets for the treatment of PBC in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as monotherapy in adults unable to tolerate UDCA. This makes elafibranor the first medicine for PBC approved for use on the NHS in nearly a decade.

26 Oct 2024

Studies reveal unique challenges faced by younger patients with colorectal cancer

Younger adults with colon cancer tend to be diagnosed at a later stage and have more aggressive types of tumors.

18 Oct 2024

New genetic variant may predict severe ulcerative colitis in patients

Abdominal pain, diarrhea, and debilitating fatigue define the daily lives of millions of people worldwide who suffer from chronic bowel disease.

17 Oct 2024

Study warns of increasing Rocky Mountain spotted fever cases among children in California

Recent cases of Rocky Mountain spotted fever in children underscore the effectiveness of mcf-NGS for early detection and timely treatment in non-endemic areas.

15 Oct 2024

Early signs of inflammatory bowel disease detected in newborns

Across the Western world, the prevalence of these chronic and serious conditions, which have no cure, is rising. In Denmark alone, 50,000 people suffer from either Crohn's disease or ulcerative colitis, which represents a doubling in cases over the past 20 years.

12 Oct 2024

University of Arkansas receives NIH grant to study situational bias in healthcare

The National Institutes of Health awarded just under $3.4 million to Anastasia Makhanova, an assistant professor of psychology at the University of Arkansas.

10 Oct 2024

Study highlights benefits and risks of doxy-PEP for STI prevention

Taking a dose of the oral antibiotic doxycycline after a high-risk sexual encounter has dramatically reduced the incidence of sexually transmitted infections (STIs) in places where the strategy is being tried.

4 Oct 2024

Oropouche virus spreads in South America as scientists warn of potential outbreaks in the U.S.

Researchers review the reemergence and range expansion of Oropouche virus in South America, highlighting risks of spread to the U.S. and need for improved diagnostic tests. Over 9,000 cases and two deaths were reported in 2024.

4 Oct 2024

Diagnostic errors affecting one in fourteen hospital patients

Harmful diagnostic errors may be occurring in as many as 1 in every 14 (7%) hospital patients - at least those receiving general medical care - suggest the findings of a single center study in the US, published online in the journal BMJ Quality & Safety.

1 Oct 2024

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Study reveals key genetic factors in Vibrio cholerae O1 that drive cholera transmission and severity, highlighting targets for novel therapeutic strategies.

26 Sep 2024