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Study identifies new tau regulators as viable therapeutic targets for Alzheimer's and other tauopathies

Neurodegenerative diseases affect millions of people worldwide and as our life expectancy increases, more individuals are expected to be affected in the coming decades.

16 Jan 2023

Research reveals how microorganisms found in the gut can worsen C. difficile infections

New research from the University of Virginia School of Medicine and collaborators reveals how microorganisms found in our guts can worsen dangerous C. difficile infections.

21 Dec 2022

Researchers use a comparative study to model RSV prevention in children

Using computational modeling, a new paper compares the benefit of maternal vaccines versus the administration of respiratory syncytial virus (RSV)-specific monoclonal antibody (mAb) therapy against RSV.

28 Nov 2022

First-of-its-kind computer model simulates a clinical trial evaluating two Alzheimer’s drugs

An estimated 6.2 million Americans ages 65 and older are living with Alzheimer's disease. The national Alzheimer's Association predicts that number to grow to 13.8 million by 2060, barring the development of medical breakthroughs that would prevent, slow or cure the debilitating disease.

2 Nov 2022

Scientists develop a pseudovirus system to deep mutational scan the full SARS-CoV-2 spike

A pseudovirus system based on deep mutational scanning determines how SARS-CoV-2 mutations can affect its ability to escape neutralization.

18 Oct 2022

UCI neuroscientists discover underlying mechanisms behind brain’s high-level work

Our ability to think, decide, remember recent events and more, comes from our brain's neocortex. Now University of California, Irvine neuroscientists have discovered key aspects of the mechanisms behind these functions.

27 Sep 2022

UW joins the Alliance for Therapies in Neuroscience to transform the fight against neurological diseases

The University of Washington has joined the Alliance for Therapies in Neuroscience (ATN), a long-term research partnership between academia and industry geared to transform the fight against brain diseases and disorders of the central nervous system.

26 Sep 2022

Testosterone supplements increase sexual impulsivity in men

A recent study provides more evidence that male sexual behavior is driven, in part, by testosterone levels.

8 Sep 2022

Study provides a comprehensive view of the genomics of all childhood ALL subtypes

Scientists have created a roadmap of the genetic mutations present in the most common childhood cancer, acute lymphoblastic leukemia (ALL).

1 Sep 2022

Here's why thinking hard exhausts you

Researchers elucidate the neuro-metabolic mechanisms responsible for cognitive fatigue that occurs following extended and intense working hours.

15 Aug 2022

Sniffing out cancer with insect olfactory neural circuits

A fascinating new preprint reports the results of examining the VOC composition from individual cell cultures derived from human oral cancers, using an experimental setup employing an insect brain with attached antenna.

11 Aug 2022

New simulator quantifies the effect of body posture and stomach motility on drug bioavailability

A common, economic, and easy method of administering drugs is orally, by swallowing a pill or capsule.

9 Aug 2022

Brain & Behavior Research Foundation recognizes exceptional research in mental illness

The Brain & Behavior Research Foundation today announced the winners of its 2022 Klerman and Freedman Prizes, recognizing exceptional clinical and basic research in mental illness.

1 Aug 2022

Decoy ACE2 receptors broadly neutralize SARS-CoV-2 variants

Researchers review current developments in preclinical studies associated with recombinant ACE2 decoy receptors against coronaviruses.

31 Jul 2022

Study offers insight into cancer cell migration and opens new possibilities for stopping it

An international research group has investigated the mechanisms of cell migration and the impact of tissue rigidity on cell positioning and steering. The research sheds light on e.g. cancer cell migration and opens new possibilities for stopping and directing it.

12 Jul 2022

Model predicts scenarios that reveal the benefit of updating COVID vaccines

In a recent study posted to the bioRxiv* preprint server, scientists analyzed the necessity of revamping the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines to tackle the current dominant circulating viral variants.

26 May 2022

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Researchers used the SARS-CoV-2 sequence against aptamers to perform the in silico selection of an aptamer against the SARS-CoV-2 S protein.

24 May 2022

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

In a recent study posted to the bioRxiv* pre-print server, researchers characterized the mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 15 (Nsp-15).

16 May 2022

$Using AI to predict how cancer may affect the probability of spinal fractures$

Using AI to predict how cancer may affect the probability of spinal fractures

As medicine continues to embrace machine learning, a new study suggests how scientists may use artificial intelligence to predict how cancer may affect the probability of fractures along the spinal column.

5 May 2022

Novel plug-and-play multi-organ chip can be customized to the patient

Engineered tissues have become a critical component for modeling diseases and testing the efficacy and safety of drugs in a human context.

27 Apr 2022