Electron Microscopy News and Research

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Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Research discusses the activity spectrum of nourseothricin and its components, S-F and S-D, against drug-resistant, gram-negative pathogens. S-F showed promising activity against NDM-1-expressing Klebsiella pneumoniae Nevada strain with minimal toxicity, and it probes the A-decoding site potentially accounting for its miscoding activity.

17 May 2023

Molecular mechanism behind a DNA repair pathway revealed

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

16 May 2023

The discovery of a novel orthonairovirus from Dermacentor silvarum ticks near the China–North Korea border

Researchers isolated a novel virus of the Orthonairovirus genus.

16 May 2023

Novel 'CLEVER' method accelerates engineering and genetic study of SARS-CoV-2 and its variants

Researchers described rapid mutagenesis and rescue of SARS-CoV-2 variants without cloning.

16 May 2023

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

15 May 2023

SARS-CoV-2 variants show altered glycan processing

Researchers examine spike-protein trimers from SARS-CoV-2 variants to compare the N (asparagine)-glycan landscape.

15 May 2023

AI used to build a 3D model of the Commander complex

University of Queensland researchers have used artificial intelligence to build a 3D map of key cell components to better understand dementia and infectious diseases including COVID-19.

11 May 2023

New drug delivery system delivers antioxidant directly to mitochondria in the liver

A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.

10 May 2023

African psychedelic plant medicine inspires new drug candidates for treating addiction and depression

Scientists have developed two new drug candidates for potentially treating addiction and depression, modeled on the pharmacology of a traditional African psychedelic plant medicine called ibogaine.

2 May 2023

Cryogenic electron microscopy helps visualize structural details of gene regulation process

LMU researchers show detailed displacement process of TBP transcription factor from DNA by Mot1 enzyme.

28 Apr 2023

Research uncovers antibodies that are still effective against new variants of SARS-CoV-2

An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2.

26 Apr 2023

Study sheds light on the mechanisms behind circadian rhythms

New research from a multidisciplinary team helps to illuminate the mechanisms behind circadian rhythms, offering new hope for dealing with jet lag, insomnia and other sleep disorders.

26 Apr 2023

Researchers take key step toward developing a gene therapy for Usher syndrome type 1F

Usher Syndrome type 1F is a rare but severe genetic disease that causes deafness, lack of balance, and progressive blindness.

26 Apr 2023

Print your own vaccine: automatic printing of microneedle patch COVID-19 mRNA vaccines

Researchers reported on the automatic printing of microneedle patch SARS-CoV-2 mRNA vaccines.

26 Apr 2023

Previously unknown mechanisms may lead to new approaches to fight viral infections

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

25 Apr 2023

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Study aimed to test the antibacterial and cytotoxic effects of bee venom-loaded chitosan nanoparticles (BV-loaded CS-NPs) against Staphylococcus aureus. The results showed that BV-loaded CS-NPs had enhanced antibacterial activity and minimal cytotoxicity, making it a promising antibiotic alternative.

24 Apr 2023

The Power of Solid-State Nuclear Magnetic Resonance in Biological Research

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Spectroscopy Award, Robert Tycko.

From Pittcon 20 Apr 2023

Study reveals molecular mechanisms that give bacteria its 'superpowers' against antibiotics

A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings.

17 Apr 2023

Salk study opens an entirely new way of thinking about cognitive decline

Brains are like puzzles, requiring many nested and codependent pieces to function well. The brain is divided into areas, each containing many millions of neurons connected across thousands of synapses.

12 Apr 2023

The emergence of tanapox in South Africa, 2022

Study describes a human case of tanapox in South Africa.

10 Apr 2023

Electron Microscopy News and Research

Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Molecular mechanism behind a DNA repair pathway revealed

The discovery of a novel orthonairovirus from Dermacentor silvarum ticks near the China–North Korea border

Novel 'CLEVER' method accelerates engineering and genetic study of SARS-CoV-2 and its variants

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

SARS-CoV-2 variants show altered glycan processing

AI used to build a 3D model of the Commander complex

New drug delivery system delivers antioxidant directly to mitochondria in the liver

African psychedelic plant medicine inspires new drug candidates for treating addiction and depression

Cryogenic electron microscopy helps visualize structural details of gene regulation process

Research uncovers antibodies that are still effective against new variants of SARS-CoV-2

Study sheds light on the mechanisms behind circadian rhythms

Researchers take key step toward developing a gene therapy for Usher syndrome type 1F

Print your own vaccine: automatic printing of microneedle patch COVID-19 mRNA vaccines

Previously unknown mechanisms may lead to new approaches to fight viral infections

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

The Power of Solid-State Nuclear Magnetic Resonance in Biological Research

Study reveals molecular mechanisms that give bacteria its 'superpowers' against antibiotics

Salk study opens an entirely new way of thinking about cognitive decline

The emergence of tanapox in South Africa, 2022

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