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The Future of Tuberculosis; An Interview with the Bill & Melinda Gates Medical Research Institute

We speak to Dr. Alemnew Dagnew from the Bill & Melinda Gates Medical Research Institute, about their tuberculosis vaccine study and the future of tuberculosis.

16 Mar 2022

At-home test for influenza is as accurate as rapid diagnostic testing in clinical settings

Home-based, self-administered tests for influenza are comparable in accuracy to rapid diagnostic tests in clinical settings, according to a recently published, peer-reviewed study.

11 Mar 2022

Specific variant of the HLA-DPB1 gene linked with poor response to allergen immunotherapy

Although sublingual immunotherapy (SLIT) has become an effective treatment option for many allergies, about 20-30% of patients don’t respond to SLIT for Japanese cedar pollinosis–a highly common disease.

7 Mar 2022

Intensive treatment for patients with Crohn's disease found to be safe

Intensive treatment for patients with Crohn's disease showed no safety differences compared to the current standard of care, according to a trial published in the journal Gastroenterology.

1 Mar 2022

Combating leukemia cells by disrupting their energy maintenance mechanism

Acute myeloid leukemia, which affects blood and bone marrow cells, is a particularly dangerous form of cancer. More than half of patients under the age of 60 die.

17 Feb 2022

Study examines how elimination of race-based adjustments in kidney function estimates impacts clinical trials

Considerable controversy surrounds race-based algorithms in medicine - such as an adjustment for Black race in equations that estimate individuals' kidney function. A new study in CJASN has examined the impact of changes to these equations on the inclusion of Black participants in kidney disease–related clinical trials, and on the results of such trials.

24 Jan 2022

Patient, beware: Some states still pushing ineffective covid antibody treatments

As the omicron variant completes its sweep across the U.S., states with scarce supplies of monoclonal antibody therapies continue to use two treatments that federal health officials warn no longer work against the highly contagious version of the virus that causes covid-19.

21 Jan 2022

Researchers illuminate the molecular landscape and clinical features of rare kidney cancer

Translocation renal cell carcinoma (tRCC) is a rare and aggressive form of kidney cancer. It accounts for about 5 percent of all renal cell carcinomas in adults and about 50 percent in children.

10 Jan 2022

SARS-CoV-2 Omicron variant's infectivity, vaccine breakthrough, and antibody resistance

A recent study uses an artificial intelligence model to investigate Omicron's mutations and its infectivity, vaccine escape capability, and susceptibility to monoclonal antibodies.

10 Jan 2022

Understanding and overcoming the challenges of chemical synthesis at a global Contract Research Organisation

In this interview, News-Medical talks to Andrew Kennedy and Jono West from Sai Life Sciences, about the work they do and how they utilise Radleys equipment in order to understand and overcome chemical synthesis challenges.

From Radleys 5 Jan 2022

Positive results from Phase 3 study of Medicago’s plant-based COVID-19 vaccine candidate announced

Medicago, a biopharmaceutical company headquartered in Quebec City, and GlaxoSmithKline today announce positive efficacy and safety results from the global Phase 3 placebo-controlled efficacy study of Medicago’s plant-based COVID-19 vaccine candidate in combination with GSK’s pandemic adjuvant, conducted in over 24,000 subjects, adults 18 years and above, across six countries.

9 Dec 2021

High-dose intravenous iron reduces heart attacks in hemodialysis patients

A new paper in Cardiovascular Research, published by Oxford University Press, indicates that iron treatments may reduce heart attacks in patients experiencing kidney failure undergoing dialysis.

8 Dec 2021

Electronic nicotine delivery systems may help some people stop smoking cigarettes

Electronic cigarettes with cigarette-like nicotine delivery may help some people stop smoking cigarettes, according to a new study by Penn State College of Medicine and Virginia Commonwealth University researchers.

8 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

A combination of two targeted cancer drugs showed unprecedented, "clinically meaningful" activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.

25 Nov 2021

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

People who received two doses of the Pfizer COVID-19 vaccine while on TNF inhibitors - a class of immunosuppressants used to treat rheumatoid arthritis and other autoimmune conditions - generated less powerful and shorter-lived antibodies against the virus that causes COVID-19 than healthy people and those on other kinds of immunosuppressants, according to a study by researchers at Washington University School of Medicine in St. Louis.

21 Nov 2021

First long-acting injectable HIV treatment appraised and approved by NICE

ViiV Healthcare, the global specialist HIV company majority owned by GlaxoSmithKline plc, with Pfizer Inc. and Shionogi Limited as shareholders, is pleased to announce that eligible people living with Human Immunodeficiency Virus (HIV) in England and Wales will soon have routine access to Vocabria (cabotegravir long-acting injection) developed by ViiV Healthcare in combination with Rekambys (rilpivirine long-acting injection), developed by Janssen Sciences Ireland UC (Janssen), one of the Janssen Pharmaceutical Companies of Johnson & Johnson.

19 Nov 2021

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Anemia is a common and sometimes debilitating problem among patients with chronic kidney disease (CKD). Anemia can occur when the kidneys become damaged, limiting the production of erythropoietin (EPO) - a hormone that signals to the body to make red blood cells.

7 Nov 2021

Pharma campaign cash delivered to key lawmakers with surgical precision

The Biden administration and Congress are embroiled in high-stakes haggling over what urgent priorities will make it into the ever-shrinking social spending bill.

27 Oct 2021

Mapping proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council Epidemiology Unit at the University of Cambridge, challenging the categorization of diseases by organ, symptoms, or clinical specialty.

15 Oct 2021