Metformin News and Research

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Metformin is the active ingredient in a drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood). It is also being studied in the treatment of cancer. It decreases the amount of glucose (a type of sugar) released into the bloodstream from the liver and increases the body’s use of the glucose. Metformin is a type of antidiabetic agent.

Further Reading

Danish studies find increased risk of optic nerve damage with diabetes medicine

Danish studies find increased risk of optic nerve damage with diabetes medicine

Two independent studies from the University of Southern Denmark (SDU) show that patients with type 2 diabetes who are treated with the drug Ozempic have an increased risk of developing damage to the optic nerve of the eye, which can lead to severe and permanent loss of vision.

16 Dec 2024

New compound HPH-15 offers promising alternative to diabetes medications

New compound HPH-15 offers promising alternative to diabetes medications

Kumamoto University scientists have unveiled a novel compound, HPH-15, with dual effects of reducing blood glucose levels and combating fat accumulation, marking a significant leap in diabetes treatment innovation.

6 Dec 2024

New framework enhances genetic prediction of drug response and side effects

New framework enhances genetic prediction of drug response and side effects

A UCLA study has outlined a new framework that researchers say would improve predictive power of genetics to determine how well a patient would respond to commonly prescribed medications as well as the severity of any side effects.

5 Dec 2024

Anti-obesity medications could help treat alcohol use disorders

Anti-obesity medications could help treat alcohol use disorders

Losing weight with anti-obesity medications (AOM) also resulted in decreased alcohol consumption for about half of the participants in a new study appearing in the current issue of JAMA Network Open.

4 Dec 2024

Holistic lifestyle interventions outshine drugs in preventing cardiometabolic diseases

Holistic lifestyle interventions outshine drugs in preventing cardiometabolic diseases

Comprehensive lifestyle interventions prevent cardiometabolic diseases effectively but face challenges in routine care and require supportive policies for lasting impact.

3 Dec 2024

Nearly half of weight loss participants reduced alcohol use after starting anti-obesity medication

Nearly half of weight loss participants reduced alcohol use after starting anti-obesity medication

Researchers evaluate changes in alcohol use after initiating antiobesity medication.

29 Nov 2024

Can fasting improve diabetes outcomes? Ramadan offers insights

Can fasting improve diabetes outcomes? Ramadan offers insights

A study during Ramadan shows intermittent fasting improves liver health, gut microbiota richness, and metabolic markers in T2DM patients. However, benefits fade quickly after fasting ends, highlighting the need for sustained interventions.

27 Nov 2024

Study reveals slower fat gain in babies exposed to gestational diabetes

Study reveals slower fat gain in babies exposed to gestational diabetes

A new study led by researchers at The University of Texas at Austin and Harvard Medical School reveals surprising findings about how babies exposed to gestational diabetes mellitus (GDM) grow during their first year of life.

20 Nov 2024

Diabetes drugs cut asthma attacks by up to 70%, reshaping treatment options

Diabetes drugs cut asthma attacks by up to 70%, reshaping treatment options

Metformin and GLP-1 receptor agonists significantly reduce asthma attacks in patients with type 2 diabetes, offering potential new treatments for asthma.

19 Nov 2024

Global gap in diabetes prevalence and treatment has widened since 1990

Global gap in diabetes prevalence and treatment has widened since 1990

Global diabetes rates have surged, particularly in low-resource areas, revealing critical gaps in treatment access and highlighting the need for improved care.

15 Nov 2024

Mortality risk higher for those diagnosed with type 2 diabetes at younger ages

Mortality risk higher for those diagnosed with type 2 diabetes at younger ages

Findings indicate younger-onset type 2 diabetes is associated with higher mortality and complications, highlighting the need for focused healthcare strategies.

4 Nov 2024

Semaglutide may reduce Alzheimer's risk in diabetics

Semaglutide may reduce Alzheimer's risk in diabetics

Researchers use real-world data in the United States to evaluate the protective role of semaglutide against Alzherimer’s disease.

25 Oct 2024

Low-carb diet may improve beta-cell function in type 2 diabetes patients

Low-carb diet may improve beta-cell function in type 2 diabetes patients

This study shows a carbohydrate-restricted diet boosts β-cell function in type 2 diabetes, offering a sustainable approach to manage the disease effectively.

24 Oct 2024

Telemedicine and low-carb diet slashes diabetes meds and drives lasting remission

Telemedicine and low-carb diet slashes diabetes meds and drives lasting remission

A five-year study on a low-carbohydrate, remote care intervention for type 2 diabetes shows significant improvements in diabetes remission, weight loss, and cardiometabolic health, reducing the need for medications.

22 Oct 2024

Metformin found safe for men with type 2 diabetes planning for parenthood

Metformin found safe for men with type 2 diabetes planning for parenthood

Potential fathers with type 2 diabetes can be reassured that taking the drug metformin is not associated with birth defects in their offspring, concludes a large study of more than 3 million pregnancies published by The BMJ today.

17 Oct 2024

CKMT2 regulates mitochondrial function and energy metabolism in type 2 diabetes

CKMT2 regulates mitochondrial function and energy metabolism in type 2 diabetes

Creatine kinase M2 (CKMT2) plays a key role in mitochondrial dysfunction in type 2 diabetes, affecting energy metabolism in skeletal muscle.

10 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

Common diabetes medication slows growth of precancerous esophageal cells, study shows

Common diabetes medication slows growth of precancerous esophageal cells, study shows

A common diabetes medication, metformin, slows the growth of precancerous cells in the oesophagus while some metabolic conditions accelerate it, suggests a new study.

16 Sep 2024

Ketogenic diet restores menstrual cycles and boosts fertility in women with PCOS

Ketogenic diet restores menstrual cycles and boosts fertility in women with PCOS

A ketogenic diet restored menstrual cycles in all women with PCOS in a study, with over half of those desiring pregnancy achieving it. The diet could be a promising approach to enhance fertility.

15 Sep 2024

Real-world evidence highlights safety profile of tirzepatide in managing type 2 diabetes

As more people with type 2 diabetes (T2D) are taking medications to help manage blood sugar levels and weight loss, concerns about whether these drugs are safe have emerged.

12 Sep 2024

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