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Targeted mRNA vaccines train the immune system to destroy cancer cells

No matter where cancer cells grow in the human body, they are a threat to our health and our lives. But instead of treating them with chemotherapy or radiation - which have undesirable side effects - what if we could train our own immune systems to kill the rogue cells?

16 Dec 2025

First-of-its-kind mRNA system switches on therapeutic genes inside targeted cells

Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells-an advance demonstrated in studies in mice that could lay the groundwork for safer, more precise treatments for cancer and other diseases.

16 Dec 2025

Scientists create light-controlled versions of cholesterol

High levels of cholesterol are linked to heart disease, stroke, and many other health problems. However, this complex and vital fatty, water insoluble molecule-a lipid-is found in every cell of the body and is not all bad news. It also regulates crucial processes that science has yet to map.

15 Dec 2025

Using sound waves to soften tumors and boost chemotherapy

Cancer is one of the leading causes of death in the U.S., second only to heart disease. But a new cancer treatment method from CU Boulder researchers uses sound waves to soften tumors and could be a potent tool against the disease.

15 Dec 2025

Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

This study shows that vacancy-engineered MoS₂ nanoflowers drive mitochondrial biogenesis in human mesenchymal stem cells by activating SIRT1–PGC-1α signaling and reducing oxidative stress. These treated cells transfer more functional mitochondria to injured recipient cells, restoring energy metabolism and redox balance in multiple in vitro models.

9 Dec 2025

Understanding the health hazards of ultrafine particles emitted by small electric home appliances

Small home appliances equipped with electric heating coils and brushed DC motors, like hair dryers, air fryers and toasters—can emit harmful tiny ultrafine particles that deteriorate indoor air quality.

8 Dec 2025

Study sheds light on how extracellular vesicles mediate intercellular communication

A new study describes a key molecular mechanism that explains how cells exchange information through extracellular vesicles (EVs), small particles with great therapeutic potential.

28 Nov 2025

Novel mRNA-based therapy may offer a new path to tackle antibiotic-resistant infections

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have reported early success with a novel mRNA-based therapy designed to combat antibiotic-resistant bacteria.

26 Nov 2025

New skin-permeable polymer delivers insulin without needles

Innovative zwitterionic polymer facilitates insulin absorption through the skin, offering a painless alternative to injections for diabetes management.

25 Nov 2025

Black cumin: A promising natural agent with potential against chronic diseases

Black cumin seeds contain diverse secondary metabolites, including thymoquinone, flavonoids, triterpenoids and alkaloids, that demonstrate broad antimicrobial, antioxidant, anti-inflammatory and anticancer activity. Early preclinical and limited clinical evidence shows therapeutic potential across chronic diseases, supported by mechanistic and structure activity relationship findings.

24 Nov 2025

New method can stop or reverse the decline of cellular energy production

Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production - a finding that could have revolutionary effects across medicine.

22 Nov 2025

RNA-based cocktail shows promise against glioblastoma

A patented RNA-based cocktail developed at the Italian Institute of Technology (IIT-Istituto Italiano di Tecnologia) has emerged as a promising active agent against tumors of the central nervous system, such as glioblastoma.

20 Nov 2025

New light-based technology arranges cellular messengers with unprecedented precision

In stunning new time-lapse videos, biological nanoparticles scoot and flit across a starry field of glowing dots. Guided by the invisible chemistry of attraction, these microscopic travelers eventually group together to form perfectly round, glowing circles on a black surface.

18 Nov 2025

Innovative CRISPR strategy resensitizes lung cancer to treatment

In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in lung cancer.

17 Nov 2025

Magnetic microrobots guide drugs directly to blood clots

Every year, 12 million people worldwide suffer a stroke; many die or are permanently impaired. Currently, drugs are administered to dissolve the thrombus that blocks the blood vessel.

14 Nov 2025

Modular magnetic microrobots achieve precision drug delivery

A magnetically guided microrobotics system is capable of navigating the body's intricate passageways and vasculature to deliver drugs with pinpoint accuracy, according to a new study.

13 Nov 2025

Breakthroughs in theranostic nanomaterials for traumatic brain injury management

Traumatic brain injury (TBI) remains one of the most pressing public health challenges, leaving millions with lasting disabilities each year.

12 Nov 2025

Breakthrough in bone regeneration using nanoparticle-stem cell hybrid

A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to significantly improve 3D bone tissue regeneration.

12 Nov 2025

Plant-based oat protein hybrid doubles iron absorption in women

Research on oat protein nanofibril-iron hybrids highlights their potential to significantly improve iron absorption, tackling global nutritional deficiencies.

12 Nov 2025

Nanoparticle vaccine eliminates HPV-induced tumors in animal model

A nanoparticle vaccine designed to fight cancers induced by human papillomavirus (HPV) eradicated tumors in an animal model of late-stage metastatic disease, UT Southwestern Medical Center scientists report in a new study published in the Proceedings of the National Academy of Sciences (PNAS).

11 Nov 2025

Nanoparticles News and Research

Targeted mRNA vaccines train the immune system to destroy cancer cells

First-of-its-kind mRNA system switches on therapeutic genes inside targeted cells

Scientists create light-controlled versions of cholesterol

Using sound waves to soften tumors and boost chemotherapy

Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

Understanding the health hazards of ultrafine particles emitted by small electric home appliances

Study sheds light on how extracellular vesicles mediate intercellular communication

Novel mRNA-based therapy may offer a new path to tackle antibiotic-resistant infections

New skin-permeable polymer delivers insulin without needles

Black cumin: A promising natural agent with potential against chronic diseases

New method can stop or reverse the decline of cellular energy production

RNA-based cocktail shows promise against glioblastoma

New light-based technology arranges cellular messengers with unprecedented precision

Innovative CRISPR strategy resensitizes lung cancer to treatment

Magnetic microrobots guide drugs directly to blood clots

Modular magnetic microrobots achieve precision drug delivery

Breakthroughs in theranostic nanomaterials for traumatic brain injury management

Breakthrough in bone regeneration using nanoparticle-stem cell hybrid

Plant-based oat protein hybrid doubles iron absorption in women

Nanoparticle vaccine eliminates HPV-induced tumors in animal model

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