Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Beckman Coulter Diagnostics expands Alzheimer’s portfolio with CE-marked p-Tau217 blood test and new high-specificity research assay

Beckman Coulter Diagnostics, a global leader in clinical diagnostics and a Danaher company, today announced it received CE Mark under IVDR for its Access p-Tau217 assay, a blood test designed to support clinical evaluation of amyloid pathology in patients with signs and symptoms of cognitive decline.

7 Jul 2026

Study identifies promising drug target to prevent neurodegenerative conditions

Parkinson's disease (PD) is the second most common form of neurodegenerative disease and afflicts more than ten million people worldwide. While current therapies address disease symptoms, they do not prevent the underlying neurodegeneration that drives the disease.

6 Jul 2026

Study compares different light therapies for treating Alzheimer's disease

The researchers treated 5‑month‑old 5xFAD mice – a model with aggressive amyloid deposition – with 810‑nm light (25 mW/cm² at the scalp, ~6.25 mW/cm² brain dose for CW, and half that for 40‑Hz due to 50% duty cycle) for 10 minutes daily over 37 days.

6 Jul 2026

McMaster researchers uncover why statins cause painful muscle side effects

Millions of people rely on statins - a medication used to lower cholesterol and reduce the risk of heart attack and stroke.

6 Jul 2026

BCG vaccine may remodel the human brain's immune environment

New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine - which is delivered through the skin to prevent tuberculosis - may remodel the human brain's immune environment, offering a potential biological explanation for previously observed associations between BCG vaccination and lower Alzheimer's disease risk.

6 Jul 2026

Swiping-based dating apps show strongest ties to compulsive use and body dissatisfaction

A meta-analysis of 27 studies involving 21,263 adults linked swiping-based dating app use to small-to-moderate adverse mental health correlates, especially compulsive use, body image concerns, and appearance-related anxiety. General well-being was not significantly associated with app use in the primary analysis, and the authors stressed that mostly cross-sectional evidence cannot prove causality.

5 Jul 2026

Researchers uncover shared olfactory mechanisms across mice and humans

Picture a mouse taking rapid, staccato sniffs of a crumb it's found while foraging for food. Now compare that with a human, leaning in for a single, deep inhale to gauge if a cantaloupe is ripe.

3 Jul 2026

Experimental drug shields nerve cells from damage caused by ALS

Amyotrophic Lateral Sclerosis, or ALS, received widespread awareness in the summer of 2014 thanks to an Ice Bucket Challenge. Millions of people participated in the challenge, drenching themselves in ice cold water to bring visibility to this devastating neurodegenerative disease and generate charitable donations for research.

3 Jul 2026

Blood circRNAs may predict Alzheimer’s before symptoms emerge

Blood-based circular RNAs showed strong potential for identifying biomarker-confirmed Alzheimer’s disease and predicting progression to symptomatic disease. When combined with pTau217, the circRNA model produced the strongest predictive performance, but larger prospective validation is still needed.

2 Jul 2026

Tailored drug combinations improve outcomes for treatment-resistant advanced melanoma

A new study led by researchers at The University of Texas MD Anderson Cancer Center has identified a way to tailor drug combinations based on specific tumor biology to improve outcomes for treatment-resistant advanced melanoma.

2 Jul 2026

USC scientists target brain inflammation to prevent Alzheimer's disease

An interdisciplinary team at the USC Center for Personalized Brain Health (CPBH) is targeting a family of enzymes that can increase the risk of inflammation in the brains of people with the APOE4 gene variation-the most significant genetic risk factor for late-onset Alzheimer's-as a way to prevent the disease.

2 Jul 2026

Study potential new therapeutic strategy for patients with ATRX-mutant gliomas

A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of the most common genetic alterations in glioma rewires the cancer cell genome to fuel tumor progression, suggesting a potential new therapeutic strategy for patients with ATRX-mutant gliomas.

1 Jul 2026

Depression-like behavior may accelerate endocrine aging in primates

A new review was published in Volume 18 of Aging on June 11, 2026, titled "Age-related dysfunctions of the neuroendocrine axes in nonhuman primates with depression-like and anxious behavior."

1 Jul 2026

Alzheimer’s disease biomarkers predict rapid cognitive decline in very old adults

Cognitive decline in very old adults has been considered for decades to be an almost inevitable consequence of aging.

1 Jul 2026

New national program targeting harmful and unnecessary medicine use in Australia

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1 Jul 2026

Blood biomarker may predict Alzheimer's progression differently in men

A blood test does not lie, exactly. It reports a number. The question raised by a new mini-review in Brain Medicine, which gathers and weighs a decade of scattered findings, is whether clinicians have been reading the same number in two different ways without realizing it.

30 Jun 2026

Study links DNA methylation to aggressive prostate cancer behavior

The prostate is the single organ most frequently afflicted by cancer in men. Prostate cancer affects approximately 4 million American men, with another 330,000 men expected to be diagnosed with the condition this year alone.

30 Jun 2026

Researchers use AI to predict rare cancer immunotherapy responses

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that an artificial intelligence (AI)-based analysis of tumor biopsies can predict responses to immunotherapy in a study of patients with rare cancers, published in the Journal for ImmunoTherapy of Cancer.

30 Jun 2026

Obesity drives distinct molecular pathway toward invasive breast cancer

A novel study has found that obesity is associated with a distinct molecular program driving the transition from early-stage, premalignant breast lesions to invasive breast cancer.

30 Jun 2026