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New blood biomarker may detect Alzheimer’s pathology more accurately

Researchers compared total plasma pTau217 with a brain-derived pTau217 assay to determine which better identifies Alzheimer’s disease–related amyloid and tau pathology. Brain-derived pTau217 showed strong diagnostic performance and appeared less affected by kidney dysfunction, supporting its potential as a more specific blood biomarker for Alzheimer’s disease.

3 Mar 2026

Heavy alcohol intake is associated with dangerous belly fat accumulation, large UK study shows

In a large UK population cohort, higher weekly alcohol consumption was dose-dependently associated with greater visceral fat mass measured by DXA, independent of total body fat. Heavy drinkers showed over 10% higher proportional visceral fat compared with lower consumption groups, a pattern linked to increased cardiometabolic risk.

26 Feb 2026

Study reveals hidden internal structure within biomolecular condensates

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes.

25 Feb 2026

AI model forecasts bone removal in cochlear implant surgery

Cochlear implant surgery helps people with severe hearing loss by placing an electronic device inside the inner ear. To reach the inner ear, surgeons must first remove part of a bone behind the ear, in a procedure called mastoidectomy.

23 Feb 2026

Rethinking cardiovascular risk assessment in women

Less artery-clogging plaque in women's arteries did not appear to protect them from heart disease compared to men, according to a study published in Circulation: Cardiovascular Imaging, an American Heart Association journal.

23 Feb 2026

Sex differences in coronary plaque burden and cardiovascular event risk revealed

Coronary artery disease (CAD) is the most common cause of death globally. In CAD, plaques composed of cholesterol, fats, calcium and other compounds accumulate and create obstructions in the coronary vessels that supply blood to the heart.

23 Feb 2026

Researchers show red blood cells drive better glucose tolerance at high altitude

Chronic hypoxia improves glucose tolerance in mice through insulin-independent mechanisms, with red blood cells acting as a major systemic glucose sink. Increased erythrocyte production and altered glycolytic flux help reduce circulating glucose while supporting oxygen delivery to tissues.

22 Feb 2026

Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier

Emerging evidence suggests reduced plasma PPP2R5C levels may serve as an early indicator of Alzheimer’s disease before overt clinical symptoms appear. The protein appears linked to tau regulation, autophagy pathways, and cognitive decline, supporting its potential diagnostic relevance.

22 Feb 2026

Blood test models predict when Alzheimer’s symptoms may start years in advance

Researchers developed plasma p-tau217–based clock models that estimate when cognitively unimpaired individuals with Alzheimer’s pathology may develop symptomatic disease. The models predicted symptom onset within about three to four years and may help improve clinical trial selection while remaining unsuitable for individual clinical decisions at present.

22 Feb 2026

New guidelines outline comprehensive care for acute pulmonary embolism

Early detection and prompt treatment of acute pulmonary embolism (PE), a sudden and potentially life-threatening blood clot that blocks arteries in the lungs, is critical.

19 Feb 2026

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

This review examines how GLP-1 receptor agonists may influence neurodegenerative disease biology through metabolic, inflammatory, mitochondrial, and proteostasis pathways. Evidence from mechanistic, preclinical, and early clinical studies suggests potential neuroprotective effects, but definitive disease-modifying benefit remains unproven.

17 Feb 2026

New AI-based approach detects fatty deposits inside coronary arteries using OCT images

Researchers have developed a new artificial intelligence-based approach for detecting fatty deposits inside coronary arteries using optical coherence tomography (OCT) images.

17 Feb 2026

CNN-based system improves lung nodule detection and classification

Lung cancer remains the leading cause of cancer-related mortality worldwide. Early detection of pulmonary nodules is crucial for timely diagnosis and effective treatment.

16 Feb 2026

Why lung cancer in never smokers is rising and how targeted detection could reduce deaths

Lung cancer in never smokers is an increasingly recognized global health issue with distinct biological drivers, environmental risk factors, and genetic susceptibilities. Improved risk modelling, targeted screening strategies, and preventive approaches are needed to enable earlier detection and reduce mortality in this growing patient group.

15 Feb 2026

Tear biosensor detects diabetic retinopathy biomarkers for early diagnosis

Tear fluid is emerging as an attractive source of diagnostic information because it can be collected easily and non-invasively.

9 Feb 2026

Metformin linked to lower odds of intermediate macular degeneration in people with diabetes

A five-year image-based study in people with type 2 diabetes found metformin use was associated with lower odds of developing intermediate age-related macular degeneration. The observational findings suggest a potential protective link but do not establish causation and warrant prospective clinical trials.

4 Feb 2026

Herpes virus infection softens cell nuclei through internal mechanical changes

A recent international research project has used advanced microscopy techniques and computational modeling to discover why virus infection changes the nuclear structures and biomechanical forces affecting the nucleus.

3 Feb 2026

New score predicts complications after mild traumatic brain injury

A study led by researchers at the Institute for Research in Biomedicine of Lleida (IRBLleida), the University of Lleida (UdL), the Universitat Oberta de Catalunya (UOC) and Arnau de Vilanova University Hospital (HUAV) has developed and internally validated a clinical prediction model called the Goliat score, which can be used by emergency services to estimate the risk of acute complications in patients suffering from minor and moderate traumatic brain injuries (TBIs).

3 Feb 2026

Innovative light control technique improves miniature endoscopic imaging capabilities

Endoscopic optical coherence tomography is widely used to visualize tissue microstructures in real time, but current probes face clear limitations.

30 Jan 2026

Cardiac MRI shows promise as a diagnostic tool for coronary heart disease

Cardiac magnetic resonance imaging (MRI) is an appropriate non-invasive procedure for functional diagnostics in patients who, as a result of basic diagnostics, are suspected of having chronic coronary heart disease (CHD) or progression of known CHD: The diagnostic accuracy of cardiac MRI is at least comparable to that of SPECT (single photon emission computed tomography) in the detection of CHD, but does not expose patients to radiation.

27 Jan 2026

Tomography News and Research

New blood biomarker may detect Alzheimer’s pathology more accurately

Heavy alcohol intake is associated with dangerous belly fat accumulation, large UK study shows

Study reveals hidden internal structure within biomolecular condensates

AI model forecasts bone removal in cochlear implant surgery

Rethinking cardiovascular risk assessment in women

Sex differences in coronary plaque burden and cardiovascular event risk revealed

Researchers show red blood cells drive better glucose tolerance at high altitude

Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier

Blood test models predict when Alzheimer’s symptoms may start years in advance

New guidelines outline comprehensive care for acute pulmonary embolism

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

New AI-based approach detects fatty deposits inside coronary arteries using OCT images

CNN-based system improves lung nodule detection and classification

Why lung cancer in never smokers is rising and how targeted detection could reduce deaths

Tear biosensor detects diabetic retinopathy biomarkers for early diagnosis

Metformin linked to lower odds of intermediate macular degeneration in people with diabetes

Herpes virus infection softens cell nuclei through internal mechanical changes

New score predicts complications after mild traumatic brain injury

Innovative light control technique improves miniature endoscopic imaging capabilities

Cardiac MRI shows promise as a diagnostic tool for coronary heart disease

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

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