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Toxin-secreting gut bacterium emerges as a driver of ulcerative colitis

A toxin-secreting gut bacterium may fuel ulcerative colitis by killing protective immune cells that maintain intestinal homeostasis, according to a new study. The findings suggest potential for new treatment strategies.

20 Nov 2025

RNA-based cocktail shows promise against glioblastoma

A patented RNA-based cocktail developed at the Italian Institute of Technology (IIT-Istituto Italiano di Tecnologia) has emerged as a promising active agent against tumors of the central nervous system, such as glioblastoma.

20 Nov 2025

Pairing antiviral therapy with immune modulation restores lung repair in lethal Influenza

Recovery from deadly influenza infection may hinge on helping the lungs heal in addition to stopping the virus, according to a new study in mice, which shows that pairing modest antiviral therapies with immune modulation can restore damaged tissues and lung function, even after severe infection has taken hold.

20 Nov 2025

New fluorescent sensor allows scientists to watch DNA damage and repair in real time

Cancer research, drug safety testing and ageing biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University.

20 Nov 2025

UK Biobank releases the world’s largest metabolomic dataset for disease research

UK Biobank has today [Thursday 20 November] released the final set of data on nearly 250 metabolites – the molecules in our blood produced by our bodies as we go about our lives – in half a million volunteers.

20 Nov 2025

Searches for “Ozempic face” surge as people look for filler-based solutions

Public interest in “Ozempic face” rose sharply from 2022 to 2025, mirrored by increased searches for nonsurgical facial filler procedures. Surgical terms showed neutral or negative associations, indicating consumers are primarily exploring filler-based solutions for GLP-1RA-related facial volume loss.

20 Nov 2025

Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

GLP-1 receptor agonists improve glycaemic control and provide renal, metabolic, and selective cardiovascular benefits in people with type 2 diabetes, based on an umbrella review of 17 meta-analyses. However, these agents consistently increase gastrointestinal adverse effects and show important distinctions between class-level outcomes and individual drug effects, particularly for semaglutide.

20 Nov 2025

Aged blood vessel cells play key role in the development of metabolic disorders

Investigators from the Center for Advanced Gerotherapeutics at Cedars-Sinai found that aged blood vessel cells play a key role in the development of metabolic disorders, including diabetes.

20 Nov 2025

Study uncovers promising therapeutic strategies against neuroendocrine prostate cancer

A new study has uncovered promising therapeutic strategies against one of the deadliest forms of prostate cancer.

20 Nov 2025

Waning immunity and falling vaccination rates fuel pertussis outbreaks

Rates of pertussis, also known as whooping cough, are surging in Texas, Florida, California, Oregon, and other states and localities across the country.

20 Nov 2025

Study compares the kidney, cardiovascular and mortality risks of three different GLP-1 RAs

Public interest in drugs known as glucagon-like peptide-1 receptor agonists, also called GLP-1 RAs, has surged in recent years, with popular types like semaglutide (sold under brand names like Ozempic and Wegovy) becoming known for their weight-loss effects.

20 Nov 2025

Focused ultrasound can be safely used in children being treated for brain cancer

Columbia University researchers are the first to show that focused ultrasound - a non-invasive technique that uses sound waves to enhance the delivery of drugs into the brain - can be safely used in children being treated for brain cancer.

19 Nov 2025

New prognostic tool can predict transplant needs in drug-induced liver injury patients

A newly developed tool, called the DILI-Inpt prognostic score, can predict patients with drug-induced liver injury who are unlikely to survive without a liver transplant.

19 Nov 2025

Cryo-EM reveals how proteins are protected during synthesis

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when sugar molecules (glycans) are attached to the maturing protein.

19 Nov 2025

Cancer cells hijack cell death enzyme to regrow after treatment

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it.

19 Nov 2025

Global report highlights persistent violence against women

Violence against women remains one of the world's most persistent and under-addressed human rights crises, with very little progress in two decades, according to a landmark report released today by the World Health Organization (WHO) and UN partners.

19 Nov 2025

New NIH grants support research on how brain fluid movement drives glioblastoma spread

Jennifer Munson, a cancer researcher at Virginia Tech's Fralin Biomedical Research Institute at VTC, has been awarded two new National Institutes of Health grants to advance greater understanding and improved treatment of a deadly brain cancer.

19 Nov 2025

Evaluating whether LIT supplementation slows cognitive decline in Alzheimer’s patients

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline such as memory loss and behavioral disturbances that severely impair quality of life. Despite decades of research, effective disease-modifying therapies remain elusive, underscoring the urgent need for novel neuroprotective strategies.

19 Nov 2025

Breakthrough in FcγRI inhibition opens path to safer autoimmune therapies

An international research group directed by UMC Utrecht have developed and characterized two first-in-class antibodies that specifically block the high-affinity IgG receptor FcγRI.

19 Nov 2025

New clinical trial shows promise for shorter TB treatment

New clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as "SPaL."

19 Nov 2025

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Drugs News and Research

Toxin-secreting gut bacterium emerges as a driver of ulcerative colitis

RNA-based cocktail shows promise against glioblastoma

Pairing antiviral therapy with immune modulation restores lung repair in lethal Influenza

New fluorescent sensor allows scientists to watch DNA damage and repair in real time

UK Biobank releases the world’s largest metabolomic dataset for disease research

Searches for “Ozempic face” surge as people look for filler-based solutions

Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

Aged blood vessel cells play key role in the development of metabolic disorders

Study uncovers promising therapeutic strategies against neuroendocrine prostate cancer

Waning immunity and falling vaccination rates fuel pertussis outbreaks

Study compares the kidney, cardiovascular and mortality risks of three different GLP-1 RAs

Focused ultrasound can be safely used in children being treated for brain cancer

New prognostic tool can predict transplant needs in drug-induced liver injury patients

Cryo-EM reveals how proteins are protected during synthesis

Cancer cells hijack cell death enzyme to regrow after treatment

Global report highlights persistent violence against women

New NIH grants support research on how brain fluid movement drives glioblastoma spread

Evaluating whether LIT supplementation slows cognitive decline in Alzheimer’s patients

Breakthrough in FcγRI inhibition opens path to safer autoimmune therapies

New clinical trial shows promise for shorter TB treatment

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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