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Rapid HIV viral load testing shows mixed effects on seeking care

According to the U.S. Centers for Disease Control and Prevention (CDC) and other sources, there are approximately 1.2 million people living with HIV in the United States, and another 1.2 to 2.2 million who are at highest risk for infection and could benefit from the preventive measure known as HIV pre-exposure prophylaxis (PrEP).

18 Dec 2025

Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. and a leading research center for diabetes and other life-threatening illnesses, have unraveled how citrin deficiency (CD), a rare genetic disorder that prevents the liver from converting food into energy efficiently, can trigger fat buildup in the liver - even in lean individuals.

18 Dec 2025

Social living allows genetic effects to spread through the gut microbiome

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published today in Nature Communications.

18 Dec 2025

New research highlights varied cold perception across body tissues

Universidad Miguel Hernández de Elche A research team led by Félix Viana, co-director of the Sensory Transduction and Nociception laboratory at the Institute for Neurosciences (IN), a joint research center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has demonstrated that the body uses different molecular mechanisms to detect cold in the skin and in internal organs.

18 Dec 2025

Researchers decipher anti-MOG antibody construction, paving way for therapies

MOG Antibody-associated Disease (MOGAD) is a rare autoimmune disease of the central nervous system. The blood of patients contains antibodies against myelin oligodendrocyte glycoprotein (MOG), a protein in the myelin layer that surrounds the neurons in the brain. It is believed that these antibodies contribute to the destruction of this protective layer in the brain.

18 Dec 2025

Genetic differences can affect the effectiveness of antibody therapies

The genome differs from person to person in thousands of positions. In some cases, this means that proteins have a different building block in certain regions, rendering some antibody-based therapies ineffective, report researchers from the University of Basel, Switzerland.

17 Dec 2025

Distant astrocytes found to play a key role in spinal cord repair

Cedars-Sinai investigators have discovered a healing mechanism that could one day be harnessed to help treat patients with spinal cord injuries, stroke, and neurological conditions such as multiple sclerosis.

17 Dec 2025

Intermittent fasting edges daily calorie cuts for blood pressure and long-term cardiovascular risk estimates

In a real-world registry study of adults with overweight or obesity, 5:2 intermittent fasting and daily calorie restriction both improved blood pressure over 12 weeks. Intermittent fasting produced modestly greater reductions in systolic and pulse pressure and a larger drop in BMI-based 30-year cardiovascular risk scores, without superior lipid or glycaemic effects.

17 Dec 2025

Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancer

St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a rare, but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT).

16 Dec 2025

Opposing protein forces fine tune mRNA stability in human cells

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - originate, as well as how to potentially treat them, according to researchers at Penn State.

16 Dec 2025

Lentilactobacillus kefiri can prevent and even reverse aging-related immune alterations

The process of aging is associated with a decline in immune functions and persistent low-level inflammation.

16 Dec 2025

Revolutionary quantum sensors could enable earlier cancer diagnosis and treatment

A revolutionary quantum sensing project that could transform cancer treatment by tracking how immune cells interact with tumors has been awarded a prestigious £2 million Future Leaders Fellowship.

16 Dec 2025

Novel cryo-EM findings could revolutionize T cell immunotherapy design

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack dangerous cells. Yet a full understanding of how they actually work has eluded researchers.

16 Dec 2025

New in vitro platform predicts drug toxicity, improving cancer treatment safety

Overcoming acquired treatment resistance is one of the major challenges in the fight against cancer. While combination therapies hold promise, their toxicity to healthy tissue remains a major hurdle. To anticipate these risks, researchers at the University of Geneva (UNIGE) have developed in vitro models of the kidneys, liver, and heart - three organs particularly sensitive to such therapies.

16 Dec 2025

Scientists map how cinnamon’s bioactives interact with cancer signaling

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible, the findings are largely limited to cell and animal models, underscoring the need for pharmacokinetic, safety, and clinical validation.

15 Dec 2025

Breast cancer disrupts stress hormone rhythms in the brain

"The brain is an exquisite sensor of what's going on in your body," says Cold Spring Harbor Laboratory Assistant Professor Jeremy Borniger. "But it requires balance. Neurons need to be active or inactive at the right times. If that rhythm goes out of sync even a little bit, it can change the function of the entire brain."

15 Dec 2025