Stroke News and Research

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A stroke is a medical emergency. Strokes happen when blood flow to your brain stops. Within minutes, brain cells begin to die. There are two kinds of stroke. The more common kind, called ischemic stroke, is caused by a blood clot that blocks or plugs a blood vessel in the brain. The other kind, called hemorrhagic stroke, is caused by a blood vessel that breaks and bleeds into the brain. "Mini-strokes" or transient ischemic attacks (TIAs), occur when the blood supply to the brain is briefly interrupted.

Researchers report results from Phase III DEFINE study for coronary heart disease

Researchers today presented results from the Phase III DEFINE (Determining the EFficacy and Tolerability of CETP INhibition with AnacEtrapib) study with Merck's investigational CETP inhibitor, anacetrapib. In the trial of 1,623 patients with coronary heart disease (CHD) or CHD risk equivalents, anacetrapib showed no significant differences from placebo in the primary safety measures studied.

18 Nov 2010

Neuralstem files NSI-189 IND with FDA for Phase I safety trials for major depression

Neuralstem, Inc. announced that it has filed an Investigational New Drug (IND) application with the United States Food and Drug Administration (FDA) to begin two Phase I safety trials to test NSI-189, its first small molecule compound, for the treatment of major depression. NSI-189 is a proprietary new chemical entity discovered by Neuralstem that stimulates new neuron growth in the hippocampus, an area of the brain that is believed to be involved in depression.

18 Nov 2010

Regado presents poster on REG3 at AHA Scientific Sessions meeting

Regado Biosciences, Inc., a privately held company leading the development of antithrombotic aptamers with active control agents, announced that Steven L. Zelenkofske, D.O., F.A.C.C., Senior Vice President and Chief Medical Officer, and Chris Rusconi, Ph.D., Senior Vice President and Chief Scientific Officer, presented a poster about REG3 at the AHA Scientific Sessions meeting.

18 Nov 2010

Sangamo presents Phase 2 clinical data in ALS at Society for Neuroscience Meeting

Sangamo BioSciences, Inc. announced today the presentation of Phase 2 clinical data from its ZFP Therapeutic program to develop SB-509, a zinc finger protein transcriptional activator (ZFP-TF) of the vascular endothelial growth factor (VEGF)-A gene as a treatment for ALS.

17 Nov 2010

St. Jude organizes tobacco cessation program for cancer survivors who smoke

Cancer survivors who smoke and need help quitting can receive help through a tobacco cessation program organized by St. Jude Children's Research Hospital.

17 Nov 2010

Cholesterol-lowering statin therapy benefits patients with calcium buildup in arteries

Rolling back suggestions from previous studies, a Johns Hopkins study of 950 healthy men and women has shown that taking daily doses of a cholesterol-lowering statin medication to protect coronary arteries and ward off heart attack or stroke may not be needed for everyone.

17 Nov 2010

Studies explore lifestyle's influence on wellness and brain health

New research is providing a deeper understanding of how individual actions - such as exercising, sensory stimulation, or drinking - influence brain health and outcomes. This new knowledge could ultimately lead to interventions in age-related cognitive declines, drug abuse, stroke, and brain injury, separate from or in combination with traditional pharmacological approaches. These findings were presented at Neuroscience 2010, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news on brain science and health.

17 Nov 2010

Cardiac surgery leads to stroke, seizure and neurological complications: Report

Strokes, seizures and other neurological complications related to heart surgery account for "considerable morbidity and mortality," Loyola University Health System neurologists report in the November issue of the journal Hospital Practice.

17 Nov 2010

Artificial retinas, thought-controlled devices and brain stimulation therapy show promise

Two experimental brain-machine technologies - deep brain stimulation coupled with physical therapy and a thought-controlled computer system-may offer new therapies for people with stroke and brain injuries, new human research shows. In addition, an animal study shows a new artificial retina may restore vision better than existing prosthetics. The findings were announced today at Neuroscience 2010, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news on brain science and health.

17 Nov 2010

Video game-based technologies allow new insight into memory, perception and motor control

New tools inspired by video games are revealing how the brain senses and responds to its surroundings, finds new human and animal research. Taking advantage of state-of-the art technologies to track and mimic real-life environments, these studies show with new detail how the brain navigates, identifies, and remembers a setting. In additional human research, scientists apply these same technological advances to help people who have experienced strokes regain skills.

17 Nov 2010

Warfarin taken along with herbal, dietary supplements may be dangerous

Herbal and dietary supplements are popular. People claim they make their joints feel better, their bones stronger, and their hearts healthier. But a recent study by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City shows that many of these people may not realize their favorite supplement, mixed with prescription medications, may be putting their lives in danger, especially if they are taking warfarin - a blood-thinning medication commonly prescribed to patients living with atrial fibrillation to lower their risk of stroke.

17 Nov 2010

TexanPlus HMO provides affordable access to cholesterol-lowering prescription drugs

TexanPlus HMO powered by CCRx, a Medicare Advantage plan offered through the Universal American's family of healthcare companies, will provide broad and affordable access to LIPITOR and CRESTOR, two popular cholesterol-lowering prescription drugs.

17 Nov 2010

Perivascular adipose tissue may lead to cardiovascular disease: Research

Researchers at the University of Cincinnati (UC) have found that fat around the outside of arteries may lead to the development of cardiovascular disease and could be linked to its onset in individuals with diabetes.

17 Nov 2010

LRI pleased with FDA Advisory Committee's approval of Benlysta for lupus

The Lupus Research Institute (LRI) and its National Coalition of state and local lupus organizations are pleased with the U.S. Food and Drug Administration (FDA) Advisory Committee's vote to recommend approval of Benlysta® for active systemic lupus erythematosus (SLE), offering patients new found hope for the first approved treatment option in more than 50 years.

17 Nov 2010

Scientists determine ways to stop damage, promote neuronal growth in spinal cord injury

If researchers could determine how to send signals to cells responding to a spinal cord injury, they might be able to stop one type of cell from doing additional damage at the injury site and instead, coax it into helping nerve cells grow.

17 Nov 2010

TRITON–TIMI 38 substudy shows prasugrel reduces overall mortality rate in ACS patients

New results from an observational substudy from TRITON–TIMI 38 presented today at the American Heart Association (AHA) Scientific Sessions annual meeting showed that patients treated with Efient/Effient (prasugrel) prior to coronary artery bypass graft surgery (CABG) had a reduced overall mortality rate compared to patients treated with Plavix (clopidogrel)

17 Nov 2010

JDRF, Amylin collaborate to support metreleptin study for type 1 diabetes

The Juvenile Diabetes Research Foundation (JDRF) and Amylin Pharmaceuticals, Inc. announced today that they entered into a research collaboration agreement to provide financial support for a clinical proof-of-concept study to investigate the effects of metreleptin, an analog of the human hormone leptin, in patients with type 1 diabetes. Researchers at The University of Texas (UT) Southwestern Medical Center will conduct the study.

17 Nov 2010

Omron supports American Heart Association's educational initiatives for hypertension treatment

Omron Healthcare today announced support for the American Heart Association's broad-based healthcare awareness campaign that will educate providers on hypertension treatment recommendations, including home blood pressure monitoring and best practices for integrating this into their standard of care.

16 Nov 2010

Stem cells for stroke: Clinical trial commences

Researchers have started the world’s first clinical trial of stem cells to treat stroke victims in Glasgow. The trial is undertaken by ReNeuron, a Guildford-based biotech company and started this weekend with an elderly man receiving an injection of 2 million stem cells into his brain. It received final approval to go ahead this year.

16 Nov 2010

Risk reduction of 20 ailments with regular exercise: Review

In a review article researchers have concluded that regular exercise cuts the risk of more than 20 illnesses. Some of these include colon cancer, heart disease, diabetes, osteoporosis and stroke said the study published in the International Journal of Clinical Practice.

16 Nov 2010

Stroke News and Research

Further Reading

Researchers report results from Phase III DEFINE study for coronary heart disease

Neuralstem files NSI-189 IND with FDA for Phase I safety trials for major depression

Regado presents poster on REG3 at AHA Scientific Sessions meeting

Sangamo presents Phase 2 clinical data in ALS at Society for Neuroscience Meeting

St. Jude organizes tobacco cessation program for cancer survivors who smoke

Cholesterol-lowering statin therapy benefits patients with calcium buildup in arteries

Studies explore lifestyle's influence on wellness and brain health

Cardiac surgery leads to stroke, seizure and neurological complications: Report

Artificial retinas, thought-controlled devices and brain stimulation therapy show promise

Video game-based technologies allow new insight into memory, perception and motor control

Warfarin taken along with herbal, dietary supplements may be dangerous

TexanPlus HMO provides affordable access to cholesterol-lowering prescription drugs

Perivascular adipose tissue may lead to cardiovascular disease: Research

LRI pleased with FDA Advisory Committee's approval of Benlysta for lupus

Scientists determine ways to stop damage, promote neuronal growth in spinal cord injury

TRITON–TIMI 38 substudy shows prasugrel reduces overall mortality rate in ACS patients

JDRF, Amylin collaborate to support metreleptin study for type 1 diabetes

Omron supports American Heart Association's educational initiatives for hypertension treatment

Stem cells for stroke: Clinical trial commences

Risk reduction of 20 ailments with regular exercise: Review

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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