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Research: Drugs used to treat lung, breast and pancreatic cancers promote drug-resistance, spur tumor growth

Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a molecule, or biomarker, called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells.

21 Apr 2014

Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers at the Stanford University School of Medicine.

21 Apr 2014

Twenty years data analysis shows patients treated with HIPEC may have improved survival rates

Meaningful long-term survival is possible for selected patients suffering from advanced cancer of the abdomen when treated with cytoreductive surgery with Hyperthermic IntraPeritoneal Chemotherapy, or HIPEC, according to a first-of-its-size analysis by physicians at Wake Forest Baptist Medical Center.

21 Apr 2014

Engineering cell-based, biological devices may selectively kill cancer cells without disrupting healthy cells

A Northwestern University synthetic biology team has created a new technology for modifying human cells to create programmable therapeutics that could travel the body and selectively target cancer and other sites of disease.

18 Apr 2014

XBiotech announces results from Phase I/II oncology study

XBiotech is announcing that results from its Phase I/II oncology study conducted at MD Anderson Cancer Center in Houston, TX were published today in Lancet Oncology. The featured article describes the outcome in 52 advanced cancer patients treated with Xilonix™, XBiotech's novel, non-cytotoxic, anti-tumor therapy.

18 Apr 2014

B1/Cdk1 protein which plays key role in cell division also boosts power of mitochondrial activity

An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process.

18 Apr 2014

Research sheds new light on the development of HPV-associated cancer

It's long been known that certain strains of human papillomavirus (HPV) cause cancer. Now, researchers at The Ohio State University have determined a new way that HPV might spark cancer development - by disrupting the human DNA sequence with repeating loops when the virus is inserted into host-cell DNA as it replicates.

17 Apr 2014

Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Neuroblastoma is one of the deadliest childhood cancers, accounting for 15 percent of pediatric cancer deaths. For patients with high-risk neuroblastomas, the five-year survival rate is 40 to 50 percent even with the most rigorous treatments available today.

17 Apr 2014

Physicist creates luminescent nanoparticle to use in photodynamic cancer therapy

A University of Texas at Arlington physicist working to create a luminescent nanoparticle to use in security-related radiation detection may have instead happened upon an advance in photodynamic cancer therapy.

17 Apr 2014

Study proposes new model for understanding how proteins bind together to facilitate cell movement

Cell movement plays an important role in a host of biological functions from embryonic development to repairing wounded tissue. It also enables cancer cells to break free from their sites of origin and migrate throughout the body.

17 Apr 2014

Researchers coax human embryonic stem cells to turn into working spinal cord cells

The sponginess of the environment where human embryonic stem cells are growing affects the type of specialized cells they eventually become, a University of Michigan study shows.

16 Apr 2014

New fiber-optic device helps clinicians diagnose cancer at early-stage

An engineering researcher at the University of Arkansas has developed an inexpensive, endoscopic microscope capable of producing high-resolution, sub-cellular images of tissue in real time.

16 Apr 2014

New blood test accurately detects presence of breast cancer and monitors response to treatment

Johns Hopkins Kimmel Cancer Center investigators report they have designed a blood test that accurately detects the presence of advanced breast cancer and also holds promise for precisely monitoring response to cancer treatment.

15 Apr 2014

EventusDx completes $2.72M financing to support development, commercialization of Octava breast cancer tests

Eventus Diagnostics, Inc. today announced completion of a $2.72 million financing. The financing was led by a new family office private investor, and existing investors also participated. Proceeds of the financing will mostly be used to support the continued development and commercialization of the company's Octava breast cancer tests.

15 Apr 2014

Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

A phase III clinical trial conducted at the Meir Medical Center in Kfar-Saba, Israel is now recruiting participants to study the effects of dietary supplement PectaSol-C modified citrus pectin (MCP) in controlling prostate specific antigen (PSA) levels in prostate cancer patients.

15 Apr 2014

New data focuses on different approaches to improve diagnosis and treatment of HCC

Epidemiological, genetic and clinical data presented today at the International Liver CongressTM 2014 are collectively focussed on different approaches designed to improve the diagnosis, staging and treatment of hepatocellular carcinoma (HCC).

15 Apr 2014

New technique of single-cell genomic analysis to reverse tissue engineering

Consider the marvel of the embryo. It begins as a glob of identical cells that change shape and function as they multiply to become the cells of our lungs, muscles, nerves and all the other specialized tissues of the body.

15 Apr 2014

Vivolux receives FDA clearance to proceed with phase I/II clinical trial of VLX600

Vivolux AB, a drug discovery company specialized in cancer treatment, announced today that the FDA has granted clearance to proceed with VLX600 into the clinical phase I/II. VLX600 is one of the company's promising projects, and which was recently published in the journal Nature Communications.

15 Apr 2014

New study identifies potential target for colorectal cancer treatment

A new study identifies a molecule that is a probable driving force in colorectal cancer and suggests that the molecule could be an important target for colorectal cancer treatment and a valuable biomarker of tumor progression.

15 Apr 2014

Researchers investigate role of microRNAs in breast cancer cells

Metastasis — the spreading of cancer cells from a primary tumor site to other parts of the body — generally leads to poorer outcomes for patients, so oncologists and researchers are constantly seeking new ways to detect and thwart this malicious process.

15 Apr 2014

Tumor News and Research

Research: Drugs used to treat lung, breast and pancreatic cancers promote drug-resistance, spur tumor growth

Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

Twenty years data analysis shows patients treated with HIPEC may have improved survival rates

Engineering cell-based, biological devices may selectively kill cancer cells without disrupting healthy cells

XBiotech announces results from Phase I/II oncology study

B1/Cdk1 protein which plays key role in cell division also boosts power of mitochondrial activity

Research sheds new light on the development of HPV-associated cancer

Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Physicist creates luminescent nanoparticle to use in photodynamic cancer therapy

Study proposes new model for understanding how proteins bind together to facilitate cell movement

Researchers coax human embryonic stem cells to turn into working spinal cord cells

New fiber-optic device helps clinicians diagnose cancer at early-stage

New blood test accurately detects presence of breast cancer and monitors response to treatment

EventusDx completes $2.72M financing to support development, commercialization of Octava breast cancer tests

Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

New data focuses on different approaches to improve diagnosis and treatment of HCC

New technique of single-cell genomic analysis to reverse tissue engineering

Vivolux receives FDA clearance to proceed with phase I/II clinical trial of VLX600

New study identifies potential target for colorectal cancer treatment

Researchers investigate role of microRNAs in breast cancer cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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