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Treating desmoplastic melanoma with immunotherapy before surgery can shrink or eliminate tumors

New results from a clinical trial co-led by UCLA investigators demonstrate how treating desmoplastic melanoma, a rare and aggressive skin cancer, with immunotherapy before surgery can dramatically shrink or even eliminate tumors, sparing patients from more aggressive surgeries and preserving their quality of life.

29 Jan 2026

Two-pronged therapeutic technology for cancer wins Pfizer Prize for Biomedical Research 2026

Whereas conventional treatments such as chemotherapy and radiotherapy show their limitations in battling certain advanced cancers, immunotherapy and therapeutic vaccines have opened up a new realm of hope for patients.

29 Jan 2026

Antiplatelet medications linked to worse outcomes in people hospitalized with a brain bleed

Analysis of hospital registry data found that people who were hospitalized due to bleeding in the brain and who had taken multiple antiplatelet medications, or medications stronger than aspirin, were more likely to die before leaving the hospital compared to those not taking any antiplatelet medication, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

Electromagnetic therapy that stimulates the brain reduces overall disability in stroke survivors

A type of therapy that stimulates specific brain pathways with electromagnetic pulses combined with physical therapy significantly reduced overall disability in stroke survivors compared to survivors who received sham (inactive) electromagnetic stimulation combined with physical therapy, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

Smartwatch app to track social interactions of stroke survivors may help maximize recovery

A smartwatch app designed to measure social interactions of hospitalized stroke survivors may enable new treatments to preserve or enhance cognition, social engagement and quality of life after a stroke, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

Her son’s injury never got its day in vaccine court. Their lawyer is now advising RFK on its overhaul.

In 2019, after a routine vaccination, 11-year-old Keithron Thomas felt a sharp pain in his shoulder and down his arm. His mother, Melanie Bostic, thought it would go away after a few days. But days turned to weeks, then months, and years.

29 Jan 2026

Brain protein CUL5 protects neurons by clearing toxic tau clumps

Researchers at UC San Francisco have identified a hazardous waste collector in the brain that disposes of the toxic clumps of tau protein that can lead to dementia.

28 Jan 2026

Exploring Targeted Protein Degradation as a New Strategy to Tackle Antimicrobial Resistance

Targeted protein degradation presents a promising strategy to address antimicrobial resistance, focusing on innovative approaches for gram-negative bacteria.

28 Jan 2026

New nanomaterial kills cancer cells via oxidative stress

Scientists at Oregon State University have developed a new nanomaterial that triggers a pair of chemical reactions inside cancer cells, killing the cells via oxidative stress while leaving healthy tissues alone.

28 Jan 2026

Newly discovered compound can advance the body's internal clock

A Japanese research team has discovered a new compound that can advance the body's internal clock—offering hope for faster recovery from jet lag and better adaptation to night-shift work.

28 Jan 2026

Novel laser focal therapy device shows promising results for prostate cancer treatment

Because treatment of the whole prostate can lead to long-term side effects in patients with prostate cancer, interest in minimally invasive, focal treatment options has been growing for certain patients.

28 Jan 2026

Transcranial magnetic stimulation can be a cost-effective treatment option for depression

A major new study has found that transcranial magnetic stimulation (TMS), which applies magnetic energy to the brain, can be a cost-effective treatment option for the NHS in treating moderate and severe forms of depression that have not responded to other treatments.

27 Jan 2026

Sleeping without pillows may help reduce nighttime eye pressure in glaucoma

Sleeping without pillows may help lower high internal eye pressure, build-up of which causes optic nerve damage and glaucoma-the leading cause of irreversible blindness worldwide–in people with the condition, suggests preliminary research, published online in the British Journal of Ophthalmology.

27 Jan 2026

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

A newly approved National Cancer Institute-funded clinical trial aims to improve survival for head and neck cancer patients whose disease returns after radiation therapy – a setback that affects up to 40% of patients and is often associated with poor outcomes.

27 Jan 2026

First topical CRISPR gene therapy corrects disease-causing mutations in human skin

Gene-editing tools like CRISPR have unlocked new treatments for previously uncurable diseases. Now, researchers at the University of British Columbia are extending those possibilities to the skin for the first time.

27 Jan 2026

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.

27 Jan 2026

Insilico Medicine and Qilu Pharmaceutical partner to develop AI-designed cardiometabolic drugs

Insilico Medicine, a clinical-stage biotechnology company powered by generative AI, and Qilu Pharmaceutical Group, a major comprehensive modern pharmaceutical enterprise in China, as well as its subsidiary Shanghai Qilu Pharmaceutical Research Center, today announced a strategic partnership on innovative drug development, leveraging Insilico's proprietary Pharma.AI platform to jointly develop small molecule inhibitors, focusing on specific targets for cardiometabolic disease management.

27 Jan 2026

Brain organoids reveal glioblastoma's secrets and therapy resistance

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

27 Jan 2026

HHCM awards $566K to advance psychedelic end-of-life care research

Healing Hearts, Changing Minds (HHCM) today announced the seven awardees of Walking Each Other Home: A Fund to Promote Psychedelic Compassion for End-of-Life Care, a $566,260 philanthropic initiative supporting innovation, compassion, and dignity for people at life's end.

27 Jan 2026

Prognostic nutritional index proposed as prognostic marker in hepatocellular carcinoma

The prognostic nutritional index (PNI), calculated from serum albumin and lymphocyte count, reflects a patient's immune-nutritional status and has been proposed as a prognostic marker in hepatocellular carcinoma (HCC).

27 Jan 2026

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Therapy News and Research

Treating desmoplastic melanoma with immunotherapy before surgery can shrink or eliminate tumors

Two-pronged therapeutic technology for cancer wins Pfizer Prize for Biomedical Research 2026

Antiplatelet medications linked to worse outcomes in people hospitalized with a brain bleed

Electromagnetic therapy that stimulates the brain reduces overall disability in stroke survivors

Smartwatch app to track social interactions of stroke survivors may help maximize recovery

Her son’s injury never got its day in vaccine court. Their lawyer is now advising RFK on its overhaul.

Brain protein CUL5 protects neurons by clearing toxic tau clumps

Exploring Targeted Protein Degradation as a New Strategy to Tackle Antimicrobial Resistance

New nanomaterial kills cancer cells via oxidative stress

Newly discovered compound can advance the body's internal clock

Novel laser focal therapy device shows promising results for prostate cancer treatment

Transcranial magnetic stimulation can be a cost-effective treatment option for depression

Sleeping without pillows may help reduce nighttime eye pressure in glaucoma

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

First topical CRISPR gene therapy corrects disease-causing mutations in human skin

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Insilico Medicine and Qilu Pharmaceutical partner to develop AI-designed cardiometabolic drugs

Brain organoids reveal glioblastoma's secrets and therapy resistance

HHCM awards $566K to advance psychedelic end-of-life care research

Prognostic nutritional index proposed as prognostic marker in hepatocellular carcinoma

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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