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Study reveals the zoonotic potential of the rat Sialodacryoadenitis virus

A new review aimed to describe the current state of knowledge on Sialodacryoadenitis virus, along with its characteristics and potential zoonotic threat.

13 Oct 2021

Anti-rheumatic drug as a potential candidate for treating COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces inflammatory cytokine storms. But an FDA-approved anti-rheumatic drug, Auranofin, used to treat autoimmune and infectious diseases, may also help serve as an antiviral treatment for COVID-19 infection.

13 Oct 2021

New study finds SARS-CoV-2 causes retinal infection

Can coronavirus disease 2019 (COVID-19) affect the eye? New research suggests the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter the eye and infect photoreceptor and retinal ganglion cells. In addition, SARS-CoV-2 infection increases the expression of several inflammatory genes, including the cytokine interleukin 33 (IL33), which is linked to COVID-19 disease and retinal degeneration.

13 Oct 2021

New high-throughput assay could help development of anti-COVID-19 drugs

In a recent study, researchers develop a new high-throughput assay that allows for rapid screening of potential inhibitors.

13 Oct 2021

Study identifies DNA mutations linking liver disease with obesity and diabetes

For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease.

13 Oct 2021

New stimulation method provides effective and personalized pain relief without side effects

Researchers at Lund University in Sweden have developed a completely new stimulation method, using ultra-thin microelectrodes, to combat severe pain.

13 Oct 2021

COVID-19 vaccination induces transient increase in cellular and antibody responses to S1 antigenic sequence

Scientists have characterized T-cell, B-cell, and IgG responses to S antigenic sequences to evaluate vaccine effectiveness.

13 Oct 2021

Using light to control micron-scale molecular movement

New research has shown how a synthetic self-made fibers can guide molecular movement that can be fuelled by light over long distances, a discovery that could pave the way for new ways to use light as a source of sustainable energy.

13 Oct 2021

Impact of BRCA1 mRNA expression on survival of patients breast and colorectal cancer

Oncotarget published "Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients" which reported that LMNB2 is a chromatin remodeling protein that also plays a role in eukaryotic cell proliferation by organizing the nuclear membrane during mitosis.

13 Oct 2021

How long does natural immunity produced by SARS-CoV-2 infection last?

A new study posted to the bioRxiv* preprint server followed the adaptive immune response in convalescent patients from Swedish and Italian cohorts—which had earlier shown long-lasting adaptive immune responses to the G614 strain—for 15 months. Here, specific antibody levels and neutralizing antibody titers were tested against variants of concern (VOCs).

12 Oct 2021

New method helps to analyze proteins during dynamic processes on biological membranes

A large proportion of biologically relevant processes take place at membranes. Studying the dynamics of these processes in real time and without disturbing the biological system is still a major methodological challenge.

12 Oct 2021

Research elucidates how chaperones display "selective promiscuity" for specific proteins

A team of researchers at the University of Massachusetts Amherst has announced a major new advance in understanding how our genetic information eventually translates into functional proteins - one of the building blocks of human life.

12 Oct 2021

Scientists develop an extremely potent siRNA with broad activity against SARS-CoVs

Researchers in Germany have developed a promising approach to suppressing the viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

12 Oct 2021

Single-genome sequencing reveals malaria parasite genetics and evolution

Understanding how malaria parasites evolve after a human is bitten by an infected mosquito is very difficult. There can be billions of individual parasites in a patient's bloodstream and traditional genetic sequencing techniques can't identify the raw material for evolution: new mutations.

12 Oct 2021

Researchers uncover how cancer cells use sugar residue to evade the immune system

A team of South Dakota State University chemistry researchers uncovered how cancer cells utilize a simple sugar residue to disguise themselves from the immune system. What they learned will help scientists develop more effective cancer therapeutics.

12 Oct 2021

New source of stem cells could help treat people with Alagille syndrome

Researchers from Sanford Burnham Prebys have discovered a new source of stem cells just outside the liver that could help treat people living with Alagille syndrome, a rare, incurable genetic disorder in which the bile ducts of the liver are absent, leading to severe liver damage and death.

12 Oct 2021