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Can human chorionic gonadotropin supplements enhance penile growth?

Whether human chorionic gonadotropin could expedite tunica albuginea restructuring to aid penile development.

4 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

IU cancer researcher receives NCI grant to examine how immune cells support breast cancer development

A breast cancer researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center received a five-year, $2.2 million grant from the National Cancer Institute to examine how certain immune cells support metastatic breast cancer development - and how to stop it.

3 Oct 2023

Optibrium releases powerful metabolism prediction capability in next generation StarDrop software

Optibrium, a leading developer of software and AI solutions for drug discovery, today launched the latest version of its drug discovery platform, StarDrop.

From Optibrium Ltd. 2 Oct 2023

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Researchers examined the antigenicity of the emerging SARS-CoV-2 subvariant BA.2.86, finding that it is not resistant to neutralizing antibodies from previously infected or vaccinated individuals, although it does show increased binding affinity to the ACE-2 receptor. The study highlights the subvariant's sensitivity and resistance to different classes of monoclonal antibodies, offering insights for future treatment and vaccine development.

2 Oct 2023

New CRISPR-based gene-editing tool could lead to better treatments for genetic disorders

A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders.

29 Sep 2023

New protein identified as substrate for histidine methylation

Proteins are subject to post-translational chemical modifications that result in functional diversity. Methylation is one such modification that is generally believed to occur on lysine and arginine residues.

29 Sep 2023

What are the pharmacological properties of black goji berries?

The pharmacological effects of the components of Lycium ruthenicum Murray fruits.

29 Sep 2023

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Researchers from the University of Texas Southwestern have developed an aerosolized, mutated form of ACE2 that effectively neutralizes various SARS-CoV-2 variants in both cell cultures and mice. The study suggests that this modified ACE2 has promising preventive and therapeutic potential against COVID-19, especially with its easy aerosolized administration.

28 Sep 2023

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Small and precise: These are the ideal characteristics for CRISPR systems, the Nobel-prize winning technology used to edit nucleic acids like RNA and DNA.

27 Sep 2023

New technology could pave the way to rapid infection testing

New technology could pave the way to a future of rapid testing in hospitals and at home for both covid and urinary tract infection.

27 Sep 2023

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Researchers used an interdisciplinary approach incorporating phylogenetics, 3D protein modeling, and plasmid design to identify and computationally design an antigen representing the core of most currently known sarbecoviruses.

27 Sep 2023

How do micronutrients influence neurological disorders?

The knowledge about micronutrients with regard to selected neurological diseases.

27 Sep 2023

Keck School of Medicine of USC to focus on Hispanic patients with NAFLD in multi-omics study

The Keck School of Medicine of USC has received funding from the National Institutes of Health as part of a five-year, $50.3 million "multi-omics" study of human health and disease involving six sites.

26 Sep 2023

Gene-silencer study could pave the way for novel cancer therapeutics

Deep inside our cells - each one complete with an identical set of genes - a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells.

26 Sep 2023

Monkeypox mimics smallpox vaccine's immune response, new study reveals

The study in Nature Communications reveals that MPOX infection triggers an anti-viral antibody response akin to that from smallpox vaccination. Utilizing a comprehensive array of ELISAs, scientists found a high level of specificity and sensitivity in detecting antibodies against both MPOX and smallpox, offering a new, accurate way to measure immune responses.

26 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

Machine learning speeds up virtual drug screening by 10-fold

Boosting virtual screening with machine learning allowed for a 10-fold time reduction in the processing of 1.56 billion drug-like molecules. Researchers from the University of Eastern Finland teamed up with industry and supercomputers to carry out one of the world's largest virtual drug screens.

22 Sep 2023

New anticancer treatment technology targets cancer cell lysosomes and overcomes drug resistance

A groundbreaking anticancer treatment technology that selectively targets cancer cell lysosomes and overcomes drug resistance has been developed by Professor Ja-Hyoung Ryu and his research team in the Department of Chemistry at UNIST.

22 Sep 2023