Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

St George Street Capital signs agreement with AstraZeneca to develop two compounds in the clinic

St George Street Capital, a UK registered charity, has signed a license agreement with AstraZeneca to develop two compounds in the clinic: one for idiopathic male infertility, and the other for renal transplant rejection. The agreement enables additional compounds to be added in the future.

From AstraZeneca 14 Oct 2019

Brain protein plays a prominent role in the maintenance of chronic pain

A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, according to research conducted at the Icahn School of Medicine at Mount Sinai and published in print October 16, in The Journal of Neuroscience.

11 Oct 2019

How do gallstones form?

The human body is known to produce stones in various locations, most commonly in the kidneys, the bladder, the gallbladder and the appendix. Many of these stones appear without any obvious reason. However, a new study published in the journal Immunity shows the whole storyline for the first time: how gallstones are formed.

9 Oct 2019

Using tape strips to obtain skin biomarkers in children with atopic dermatitis

Applying strips of adhesive tape to skin lesions and non-lesional skin is a non-invasive way to obtain biomarkers to track the severity of early-onset pediatric eczema or atopic dermatitis in infants and young children, researchers report for the first time.

9 Oct 2019

Blocking a protein in immune cells may help reduce risk of heart attack and stroke

Blocking the mineralocorticoid receptor (MR)- a protein that helps maintain normal levels of salt and water in the body- in immune cells may help reduce the risk of heart attack and stroke by improving blood vessel health.

7 Oct 2019

Cincinnati Children's receives NIH grant renewal for collaborative research into eosinophilic disorders

Cincinnati Children's Hospital Medical Center has received a 5-year, $7.57 million grant renewal from the National Institutes of Health to continue leading a consortium of organizations from around the country that will conduct clinical research into eosinophilic gastrointestinal disorders.

7 Oct 2019

New genome-wide association study shines light on genetic risk factors for gout

Researchers, using a method called genome-wide association study, have illuminated the genetic underpinnings of high serum urate, the blood condition that brings on gout.

7 Oct 2019

Penn Medicine awarded $22 million to apply scientific solutions to reverse opioid crisis

The nation has been grappling with the opioid epidemic for years - and the city of Philadelphia has been hit hard by the crisis. While data is showing slight declines in overdose deaths, the opioid crisis remains a public health emergency.

4 Oct 2019

Even diet drinks increase the risk of type 2 diabetes, finds study

Drinking more than two artificially sweetened or sugary soft drinks each day may increase the risk of diabetes, say Harvard researchers.

4 Oct 2019

Kibow Biotech celebrates 22nd anniversary with plans to expand its product portfolio

Kibow® Biotech Inc, a pioneering probiotic company in gut modulation with its novel "Enteric Dialysis®" technology platform, is celebrating its 22-year anniversary on October 1st, 2019.

From Kibow Biotech Inc. 4 Oct 2019

Experts discuss sex-specific sensitivity to key blood pressure hormone

Aldosterone is a steroid hormone important to the regulation of salt, fluid and potassium in the body.

4 Oct 2019

Long-term study data shows DBS is effective for patients with treatment-resistant depression

A study published online on Friday, October 4, in the American Journal of Psychiatry found that deep brain stimulation (DBS) of an area in the brain called the subcallosal cingulate (SCC) provides a robust antidepressant effect that is sustained over a long period of time in patients with treatment-resistant depression--the most severely depressed patients who have not responded to other treatments.

4 Oct 2019

Short-term probiotic therapy regimen may improve symptoms of gout, kidney disease

New research suggests that an individualized probiotic therapy regimen may improve symptoms of gout, gout-related kidney disease and other signs of metabolic syndrome.

4 Oct 2019

Chronic inflammation of the placenta linked to African-American preterm births

African-American infants are twice as likely to die in the first year of life than white infants, for reasons that are complex and not well understood. Results from a recent study suggest that specific abnormalities in the placenta from African-American preterm births may hold clues to the physical mechanisms behind racial disparities in preemie health outcomes.

3 Oct 2019

Mount Sinai researchers discover how DNA polymerase delta duplicates the genome

Mount Sinai researchers have discovered how the enzyme DNA polymerase delta works to duplicate the genome that cells hand down from one generation to the next. In a study published in Nature Structural & Molecular Biology, the team also reported how certain mutations can modulate the activity of this enzyme, leading to cancers and other diseases.

3 Oct 2019

UIC receives $2.8 million NIH funding to tackle opioid use among people with kidney disease

The University of Illinois at Chicago has received $2.8 million in funding from the National Institutes of Health to investigate non-opioid pain management strategies for people with kidney disease, which affects about 15% of adults in the U.S.

3 Oct 2019

Increased intake of dietary fiber lowers risk of hypertension and type 2 diabetes

Dietary fiber has been found to reduce the risk of high blood pressure and type 2 diabetes in a study presented at the American College of Cardiology Middle East Conference 2019.

3 Oct 2019

Novel viral vector improves gene therapy for sickle cell disease

Researchers at the National Institutes of Health (NIH) have developed a unique, improved lentiviral vector for use in gene therapy for sickle cell disease.

3 Oct 2019

Innovative compound kills cancer cells, minimizes damage to normal tissues

Most of the current clinical anti-tumor drugs used in chemotherapy move around in the patient's blood after intake and are unable to pinpoint the targeted tumor. As a result, while killing the tumor cells, the healthy cells may also be killed as "collateral damage", leading to undesired side effects.

3 Oct 2019

Study shows how opt-out organ donation could affect transplant waiting lists in the U.S.

Every year in the United States, about 7,500 people die while waiting for an organ transplant, and that number is expected to increase in coming years as demographics shift.

3 Oct 2019

Nephrology News and Research

Further Reading

St George Street Capital signs agreement with AstraZeneca to develop two compounds in the clinic

Brain protein plays a prominent role in the maintenance of chronic pain

How do gallstones form?

Using tape strips to obtain skin biomarkers in children with atopic dermatitis

Blocking a protein in immune cells may help reduce risk of heart attack and stroke

Cincinnati Children's receives NIH grant renewal for collaborative research into eosinophilic disorders

New genome-wide association study shines light on genetic risk factors for gout

Penn Medicine awarded $22 million to apply scientific solutions to reverse opioid crisis

Even diet drinks increase the risk of type 2 diabetes, finds study

Kibow Biotech celebrates 22nd anniversary with plans to expand its product portfolio

Experts discuss sex-specific sensitivity to key blood pressure hormone

Long-term study data shows DBS is effective for patients with treatment-resistant depression

Short-term probiotic therapy regimen may improve symptoms of gout, kidney disease

Chronic inflammation of the placenta linked to African-American preterm births

Mount Sinai researchers discover how DNA polymerase delta duplicates the genome

UIC receives $2.8 million NIH funding to tackle opioid use among people with kidney disease

Increased intake of dietary fiber lowers risk of hypertension and type 2 diabetes

Novel viral vector improves gene therapy for sickle cell disease

Innovative compound kills cancer cells, minimizes damage to normal tissues

Study shows how opt-out organ donation could affect transplant waiting lists in the U.S.

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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