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Breast cancer survivors face accelerated aging tied to tumors and treatment

Accelerated aging in breast cancer survivors is linked to treatments and tumor characteristics, with implications for long-term care and quality of life.

20 Mar 2025

Pitt researchers develop a new way to profile pediatric brain tumors

Researchers and pediatric neurosurgeons at the University of Pittsburgh School of Medicine and UPMC Children's Hospital of Pittsburgh developed a new way to profile brain cancers in children, paving the way for improved diagnostics and treatments.

19 Mar 2025

Study reveals how B cells safeguard high-affinity antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

19 Mar 2025

Clinical trial investigates osteoporosis medication for type 1 diabetes

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States and a top research center for diabetes and other life-threatening illnesses, is leading a phase 1/2 clinical trial investigating an osteoporosis medication as a way to improve beta cell health in people with early type 1 diabetes.

19 Mar 2025

CB1R inhibition shows promise in protecting gut barrier from alcohol damage

Heavy alcohol consumption is a leading cause of gastrointestinal diseases, with binge drinking linked to increased intestinal permeability-a condition commonly known as "leaky gut."

19 Mar 2025

Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments

The findings come from the most comprehensive computer model of brain metabolism to date, which incorporates more than 16,800 biochemical interactions between proteins and chemicals across brain cells, supporting cells, and the blood.

19 Mar 2025

Moffitt researchers discover new vaccine strategy for treating specific type of breast cancer

Moffitt Cancer Center researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer.

18 Mar 2025

UZH researchers develop technology to test 25 antibodies in a single mouse

New active ingredients such as antibodies are usually tested individually in laboratory animals. Researchers at UZH have now developed a technology that can be used to test around 25 antibodies simultaneously in a single mouse.

18 Mar 2025

Biomanufacturing platform offers a sustainable alternative to synthesizing peptide-based pharmaceuticals

To tackle the inequity in medication access, a societal issue especially in developing nations, a team of undergraduate student-researchers at the University of Ottawa has developed a new biomanufacturing platform called Phytogene.

18 Mar 2025

Discontinuing heart failure medications increases risk of heart-related death

Patients who have been treated for heart failure and experience an improvement of their pump function, are still at higher risk of heart-related death or hospitalization if they stop taking heart failure medications.

17 Mar 2025

Frequently asked questions about BioAFM

Do you have a question about BioAFM? This article will tell you everything you need to know.

From Bruker Nano Surfaces and Metrology 17 Mar 2025

Novel cyclic peptide antagonist can be a promising therapeutic approach for MASH

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.

14 Mar 2025

Breakthrough peptide inhibitor effective against multiple SARS-CoV-2 variants

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors.

14 Mar 2025

Malnutrition in heart failure patients associated with diminished GDMT prescription rates

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at identifying crucial gaps in guideline-directed medical therapy (GDMT) application among malnourished patients at Beijing Anzhen Hospital.

14 Mar 2025

New laboratory tool identifies viruses to combat Staphylococcus aureus

A newly developed laboratory tool can, within hours, help to identify specific viruses which can be used to destroy variants of the dangerous pathogenic bacteria Staphylococcus aureus.

14 Mar 2025

New therapeutic approach shows promise for pediatric high-grade gliomas

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than 18 months after diagnosis and limited treatment options.

14 Mar 2025

What can you do with a BioAFM instrument?

Even more answers to help understand how BioAFM can be used!

From Bruker Nano Surfaces and Metrology 14 Mar 2025

Scientists reveal how Epstein-Barr virus reactivation triggers MIS-C in children

Scientists reveal that reactivation of Epstein-Barr virus (EBV), driven by TGFβ-induced immune suppression, is a key driver of multisystem inflammatory syndrome in children (MIS-C) following COVID-19. Blocking TGFβ may offer a potential new treatment for this life-threatening condition.

13 Mar 2025

How gut health shapes heart disease risk — and what you can do about it

A new review highlights how gut microbiome imbalances contribute to cardiovascular disease by altering short-chain fatty acids, TMAO, and inflammatory pathways. The study emphasizes the potential of prebiotics, probiotics, and dietary changes to restore gut health and reduce heart disease risk.

13 Mar 2025

Targeting MARCO enhances cancer immunotherapy effectiveness

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO.

13 Mar 2025