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Researchers create artificial tendons in vitro from human stem cells

Researchers from Tokyo Medical and Dental develop artificial tendons in vitro from human stem cells that could fix common tendon injuries such as Achilles tendon rupture.

23 Feb 2022

Dotmatics releases Platform 22.1

Latest Platform delivers new capabilities to streamline lab workflows and support customers’ data-informed decision making.

From Dotmatics 23 Feb 2022

Unvaccinated students have eight times higher incidence of COVID-19 infection, study finds

Unvaccinated students had eight times the incidence of COVID-19 infection compared to vaccinated students in a North Carolina independent school, according to a study by the ABC Science Collaborative appearing online Feb. 22 in the journal Pediatrics.

22 Feb 2022

New mutation may define a high-risk subtype of pediatric acute myeloid leukemia

A new mutation was identified in 9 percent of relapsed cases of pediatric acute myeloid leukemia (AML) that may define a new subtype of the disease.

17 Feb 2022

Messenger RNA can be used at low doses to regenerate bone without side effects

Although fractures normally heal, bone will not regenerate under several circumstances. When bone does not regenerate, major clinical problems could result, including amputation.

17 Feb 2022

Researchers discover a new and unconventional nuclear function for cancer microRNA

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the brain.

16 Feb 2022

Mechanism of SARS-CoV-2 Nsp1 interaction with ribosomal complexes

In a recent study posted to the bioRxiv* preprint server, the team of researchers explored the protein-protein interaction between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 1 (Nsp1) and host 40S and 43S ribosomal subunits.

15 Feb 2022

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

In a new study, a team of researchers demonstrated multiple site-directed mutagenesis as an efficient, easy, and more economically viable alternative to commercial gene synthesis to highlight how specific residues can contribute to the molecular structure and functioning of proteins.

15 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

RNA capping mechanism of SARS-CoV-2 unveiled

In a recent study posted to the bioRxiv* preprint server, researchers elucidated the mechanism of ribonucleic acid (RNA) capping in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

14 Feb 2022

Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates G protein-coupled receptors (GPCRs) called beta-adrenergic receptors (β-ARs).

14 Feb 2022

Novel wearable soft robotic armband could be a game changer for users of prosthetic hands

Typing on a keyboard, pressing buttons on a remote control or braiding a child's hair has remained elusive for prosthetic hand users.

11 Feb 2022

Showcasing STEM Women in Medical Science

Every year, the UN celebrates the International Day of Women and Girls in Science. For 2022, the focus is placed on recognizing the role women and girls play in STEM as beneficiaries and as agents of change.

11 Feb 2022

Researchers identify and characterize a previously unrecognized key player in cancer evolution

Researchers led by bioengineers at the University of California San Diego have identified and characterized a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome.

9 Feb 2022

Research may lead to the development of effective fasting-based therapies

Voluntary fasting, for example interval fasting, is beneficial to health for many people, depending on their individual condition. For example, controlled periods of starvation can prevent and improve diseases such as diabetes and obesity.

9 Feb 2022

Two peanut allergy treatments for children found to be highly effective at inducing remission

Researchers have discovered two peanut allergy treatments for children that are both highly effective at inducing remission.

7 Feb 2022

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

In a recent study posted to the bioRxiv* pre-print server, a team of researchers demonstrated that ubiquitin-specific peptidase 22 (USP22) is a crucial regulator of basal interferon (IFN) signaling in native human intestinal epithelial cells (hIECs).

7 Feb 2022

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

A genome study undertaken by Johns Hopkins Kimmel Cancer Center researchers to look for variants in a gene considered a fundamental building block for microscopic structures that synthesize proteins took a surprising twist.

2 Feb 2022

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

In a new study, a team of researchers used co-immunoprecipitation and in vitro interaction assays to identify the molecular basis of interaction of SARS-CoV-2 non-structural protein 2 with eIF4E-homologous protein (4EHP)-GRB10-interacting glycine-tyrosine-phenylalanine domain protein 2 complex, involved in microRNA-mediated gene silencing in human cells.

1 Feb 2022

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

The Damon Runyon Cancer Research Foundation has announced its newest cohort of Damon Runyon Fellows, 13 outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

29 Jan 2022

Translation News and Research

Researchers create artificial tendons in vitro from human stem cells

Dotmatics releases Platform 22.1

Unvaccinated students have eight times higher incidence of COVID-19 infection, study finds

New mutation may define a high-risk subtype of pediatric acute myeloid leukemia

Messenger RNA can be used at low doses to regenerate bone without side effects

Researchers discover a new and unconventional nuclear function for cancer microRNA

Mechanism of SARS-CoV-2 Nsp1 interaction with ribosomal complexes

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

RNA capping mechanism of SARS-CoV-2 unveiled

Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

Novel wearable soft robotic armband could be a game changer for users of prosthetic hands

Showcasing STEM Women in Medical Science

Researchers identify and characterize a previously unrecognized key player in cancer evolution

Research may lead to the development of effective fasting-based therapies

Two peanut allergy treatments for children found to be highly effective at inducing remission

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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