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Technique for genetically modifying blood stem cells brings cure for blood diseases closer

The condition of mice with a genetic blood disease called beta-thalassemia improved significantly following treatment of their blood forming cells with a gene that enabled them to produce the type of hemoglobin normally found only in the fetus.

12 Oct 2004

Transparent gel could soon become the first and best choice for sealing corneal incisions

The substance, known as a hydrogel, promises to be a useful tool in the kit used for the most common of ophthalmic surgeries: cataract removal. Currently, 11 million such surgeries are performed worldwide annually, a figure expected to increase as the world's population grows older.

12 Oct 2004

Protein called Mrp4 blocks the access of the anti-cancer drug topotecan into the brain

A protein called Mrp4 blocks the access of the anti-cancer drug topotecan into the brain by transporting this agent back into the bloodstream, thus reducing the ability of this agent to reach tumors.

11 Oct 2004

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

A team of University of Florida researchers has created tiny hybrid particles that can speedily root out even one isolated E. coli bacterium lurking in ground beef or provide a crucial early warning alarm for bacteria used as agents of bioterrorism and for early disease diagnosis.

11 Oct 2004

Atheromatosis, which lies behind heart attacks, stroke, and other cardiovascular problems, has a major impact on public health

These two diseases are completely different from each other, but they do have one common denominator: inflammation. Researchers at Lund University in Sweden can now show that it might also be possible to treat them with the same drug.

10 Oct 2004

Studies reveal complex molecular choreography with implications for human health and disease

As interactions of cellular proteins increasingly take center stage in basic biomedical research, studies are revealing a complex molecular choreography with implications for human health and disease.

10 Oct 2004

Discovery could lead to the creation of naturally decaffeinated coffee plants

Chemists at Emory University have made an important advance in harnessing the ability of bacteria to make new molecules, and their discovery could eventually lead to the creation of naturally decaffeinated coffee plants.

10 Oct 2004

Researchers have found a starting point to establishing the genetic basis for sinus disease

In a three-year analysis of more than 10,500 genes, one-third of the human genome, researchers at Johns Hopkins have found a starting point to establishing the genetic basis for sinus disease and the growth of nasal polyps, illnesses not well understood despite their prevalence.

8 Oct 2004

Research shows C. botulinum uses SONO to detect nitric oxide

A deadly bacterium's defense against a mortal molecular enemy illuminates the origins and structure of a vital protein involved in human cell signaling, University of Texas Medical School scientists report in Science Express.

8 Oct 2004

Researchers identify new sulfur-containing scent molecules in sweat

Sometimes, people just don't smell good – and not only in the figurative sense. The sense of smell plays an important role in interpersonal relations.

7 Oct 2004

$10 million to establish a multidisciplinary research program in cancer nanotechnology

The National Institutes of Health (NIH) has awarded scientists from Emory University and the Georgia Institute of Technology two new collaborative research grants, totaling nearly $10 million, to establish a multidisciplinary research program in cancer nanotechnology and to develop a new class of nanoparticles for molecular and cellular imaging.

6 Oct 2004

Research helps to understand the basic mechanism that underlies how neurons communicate

Nerve cells with a mutant calcium channel don't communicate as effectively as those with a normal calcium channel, according Saint Louis University research that is published in the Proceedings of the National Academy of Sciences Online Early Edition the week of Oct. 4.

5 Oct 2004

Richard Axel has won the 2004 Nobel Prize in physiology or medicine

Richard Axel of the Columbia University Medical Center has won the 2004 Nobel Prize in Physiology or Medicine along with Linda B. Buck of the Fred Hutchinson Cancer Research Center for clarifying how the olfactory system works.

5 Oct 2004

Linda Buck has been named winner of the 2004 Nobel Prize in physiology or medicine

Linda Buck, Ph.D., a member of Fred Hutchinson Cancer Research Center's Basic Sciences Division, has been named winner of the 2004 Nobel Prize in physiology or medicine.

5 Oct 2004

Researchers are studying a vaccine that, in the future, could be the first to treat advanced malignant melanoma

Unlike traditional vaccines, cancer vaccines are not meant to be given to healthy people to prevent cancer. Rather, they are meant to be used in sick patients to strengthen their immune system to better fight the cancer.

4 Oct 2004

FDA fast tracks Genaera's drug for the treatment of wet age-related macular degeneration

Genaera Corporation has announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to squalamine, an intravenously administered, first in class, small molecule anti-angiogenic drug for the treatment of "wet" age-related macular degeneration (AMD).

4 Oct 2004

Researchers show gossypol – a drug refined from cottonseed oil is a cancer treatment booster

New research has opened up the prospect that gossypol – a drug refined from cottonseed oil and previously tried and abandoned as a male contraceptive – could boost the effectiveness of treatment for prostate tumours and possibly other common cancers as well.

30 Sep 2004

Berkeley searches for AIDS cure in a Samoan indigenous tree

The University of California, Berkeley, has signed an agreement with the Samoan government to isolate from an indigenous tree the gene for a promising anti-AIDS drug and to share any royalties from sale of a gene-derived drug with the people of Samoa.

30 Sep 2004

New technology to diagnose, treat deadly diseases

By developing a new technology to analyze proteins in single human cells, York University professor Sergey Krylov hopes to create a diagnostic ‘Swiss Army Knife’ that can eventually help to diagnose and treat a variety of currently incurable diseases like cancer, diabetes, Parkinson’s and Alzheimer’s.

29 Sep 2004

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Researchers targeted Nef, a protein responsible for accelerating the development of acquired immunodeficiency syndrome, or AIDS. Nef was targeted with small molecules synthesized by the researchers – molecules that disrupted Nef’s interaction with other proteins.

26 Sep 2004

Molecule News and Research

Technique for genetically modifying blood stem cells brings cure for blood diseases closer

Transparent gel could soon become the first and best choice for sealing corneal incisions

Protein called Mrp4 blocks the access of the anti-cancer drug topotecan into the brain

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

Atheromatosis, which lies behind heart attacks, stroke, and other cardiovascular problems, has a major impact on public health

Studies reveal complex molecular choreography with implications for human health and disease

Discovery could lead to the creation of naturally decaffeinated coffee plants

Researchers have found a starting point to establishing the genetic basis for sinus disease

Research shows C. botulinum uses SONO to detect nitric oxide

Researchers identify new sulfur-containing scent molecules in sweat

$10 million to establish a multidisciplinary research program in cancer nanotechnology

Research helps to understand the basic mechanism that underlies how neurons communicate

Richard Axel has won the 2004 Nobel Prize in physiology or medicine

Linda Buck has been named winner of the 2004 Nobel Prize in physiology or medicine

Researchers are studying a vaccine that, in the future, could be the first to treat advanced malignant melanoma

FDA fast tracks Genaera's drug for the treatment of wet age-related macular degeneration

Researchers show gossypol – a drug refined from cottonseed oil is a cancer treatment booster

Berkeley searches for AIDS cure in a Samoan indigenous tree

New technology to diagnose, treat deadly diseases

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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