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Myriad Genetics awarded a $14.2 million contract for AIDS and hepatitis research

Myriad Genetics has announced that it has been awarded a five-year, $14.2 million contract by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

10 Jul 2004

The structure of AGT shows how one human protein reduces the potency of chemotherapy

The fine details of this x-ray structure may help scientists find ways to fight certain cancers, such as brain tumors, which express high levels of AGT making them resistant to chemotherapy.

9 Jul 2004

Chromatin array a new technology for examining DNA

A new technique for examining DNA is giving scientists a more detailed picture of which genes have the propensity for activation, offering a new tool for understanding how genes function and possibly for diagnosing disease.

8 Jul 2004

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Treatment with a new dual cell cycle and angiogenesis pathway inhibitor blocks VEGF-induced vascular permeability, inhibits tumour angiogenesis and induces apoptosis in human tumour models

7 Jul 2004

Key proteins that regulate neurofibromatosis could be targets for new drugs

More than 100,000 Americans suffer from the painful and debilitating genetic disorder known as neurofibromatosis, or NF, which causes tumors to grow in various types of nerve tissue throughout the body.

7 Jul 2004

Research to unravel exactly what is going on chemically, when Alzheimer's sets in

Science understands Alzheimer's disease as the progressive decline of a particular region of the brain. But the underlying mechanisms leading to this decline are still very much a mystery.

7 Jul 2004

Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

Scientists at The Scripps Research Institute have described the regulatory mechanism of an important human protein called Rac that controls a number of biological processes and is directly implicated in several human diseases.

2 Jul 2004

How DNA repair machinery detects and corrects errors in DNA replication

Biochemists at Duke University Medical Center have discovered key components that enable the cell's DNA repair machinery to adeptly launch its action in either direction along a DNA strand to strip out faulty DNA.

2 Jul 2004

Three-dimensional cryo-electron microscope may help guide the design of new antibiotics

Understanding the last step of protein synthesis – the basic process of translating DNA into its final protein product – just became more clear both literally and figuratively.

1 Jul 2004

Protein research may help develop new antibiotics

New findings about a protein that keeps cells alive by opening and closing pores within a cell's membrane may open the door to the development of new antibiotics.

30 Jun 2004

Relatively difficult for the AIDS virus to develop resistance to the drug, tenofovir, or the DAPY (diarylpyrimidine) family of compounds

HIV is a moving target, unpredictably changing direction to elude anti-AIDS drugs, but researchers at Rutgers are clearly on the track of solutions to combat HIV drug resistance.

29 Jun 2004

RNA enzyme research may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars

Research aimed at teasing apart the workings of RNA enzymes eventually may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars, according to University of Michigan researcher Nils Walter.

29 Jun 2004

Continued commercial development of research into DNA repair

Recent developments have greatly improved the understanding of the mechanisms used by cells to identify and repair breaks in DNA, and the potential for drugs that target DNA repair in the treatment of a range of human diseases including cancer.

28 Jun 2004

Blood hormone may be key to appetite suppression and obesity control

How the body naturally regulates appetite through the presence of a blood hormone may offer the prospect of a safer and more effective method of weight control, according to Dr. Leonard Firestone of Manhattan Pharmaceuticals.

28 Jun 2004

A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive

Physicians may be able to make early decisions on the best treatment for breast cancer, thanks to research published in Breast Cancer Research today.

28 Jun 2004

Treating cocaine addiction with a virus

Scientists at The Scripps Research Institute have designed a potentially valuable tool for treating cocaine addiction by creating a modified "phage" virus that soaks up the drug inside the brain.

24 Jun 2004

Genetic variation that doubles the risk for rheumatoid arthritis

A team of researchers has discovered a genetic variation that doubles the risk for rheumatoid arthritis (RA).

24 Jun 2004

Genetically engineering viruses to carry a suicide gene into ovarian cancer cells

Genetically engineering viruses to carry a suicide gene into ovarian cancer cells could become a potent way to tackle the disease, a leading Cancer Research UK scientist reveals at a conference in Glasgow today (Tuesday).

22 Jun 2004

Paclitaxel analog kills more cancer cells than natural product

Paclitaxel, a natural compound from yew trees, is the world's best-selling anticancer drug. Several analogs are in clinical trial, with others in preclinical development. One problem that paclitaxel and all its analogs share, however, is that they are all highly complex compounds, and cannot be prepared synthetically in a commercially viable way.

21 Jun 2004

New gene found in genetic wasteland

In a region of DNA long considered a genetic wasteland, Harvard Medical School researchers have discovered a new class of gene.

20 Jun 2004

Molecule News and Research

Myriad Genetics awarded a $14.2 million contract for AIDS and hepatitis research

The structure of AGT shows how one human protein reduces the potency of chemotherapy

Chromatin array a new technology for examining DNA

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Key proteins that regulate neurofibromatosis could be targets for new drugs

Research to unravel exactly what is going on chemically, when Alzheimer's sets in

Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

How DNA repair machinery detects and corrects errors in DNA replication

Three-dimensional cryo-electron microscope may help guide the design of new antibiotics

Protein research may help develop new antibiotics

Relatively difficult for the AIDS virus to develop resistance to the drug, tenofovir, or the DAPY (diarylpyrimidine) family of compounds

RNA enzyme research may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars

Continued commercial development of research into DNA repair

Blood hormone may be key to appetite suppression and obesity control

A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive

Treating cocaine addiction with a virus

Genetic variation that doubles the risk for rheumatoid arthritis

Genetically engineering viruses to carry a suicide gene into ovarian cancer cells

Paclitaxel analog kills more cancer cells than natural product

New gene found in genetic wasteland

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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