Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Lower levels of vitamin D predict extent of coronary artery disease

Vitamin D deficiency is an independent risk factor for heart disease with lower levels of vitamin D being associated with a higher presence and severity of coronary artery disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

TG2 protein is a key mediator in Porphyromonas gingivalis infection, study finds

Scientists at Forsyth, along with a colleague from Northwestern University, have discovered that the protein, Transgultaminase 2 (TG2), is a key component in the process of gum disease. TG2 is widely distributed inside and outside of human cells. The scientists found that blocking some associations of TG2 prevents the bacteria Porphyromonas gingivalis (PG) from adhering to cells. This insight may one day help lead to novel therapies to prevent gum disease caused by PG.

26 Mar 2014

Amgen announces results from Phase 3 TESLA Trial of evolocumab in patients with HoFH

Amgen (NASDAQ: AMGN) today announced that the Phase 3 TESLA (Trial Evaluating PCSK9 Antibody in Subjects with LDL Receptor Abnormalities) trial evaluating evolocumab met its primary endpoint of the percent reduction from baseline at week 12 in low-density lipoprotein cholesterol (LDL-C).

19 Mar 2014

Research on diverse health benefits of oats in protecting heart

Eleven top scientists from around the globe presented the latest findings on the powerful compounds found in oats in a scientific session titled, Physicochemical Properties and Biological Functionality of Oats, at the 247th Annual Conference of the American Chemical Society in Dallas, TX

17 Mar 2014

Researchers create statistical model to predict whether heart scans are useful in prescribing statins

As long as inexpensive statins, which lower cholesterol, are readily available and patients don't mind taking them, it doesn't make sense to do a heart scan to measure how much plaque has built up in a patient's coronary arteries before prescribing the pills, according to a new study by researchers at UC San Francisco.

17 Mar 2014

Researchers discover certain proteins in osteoclasts that may be used to destroy cardiovascular calcification

Cardiovascular calcification (deposits of minerals in heart valves and blood vessels) is a primary contributor to heart disease, the leading cause of death among both men and women in the United States according the Centers for Disease Control and Prevention (CDC).

17 Mar 2014

Women who experience gestational diabetes may face increased risk of heart disease later in life

Women who experience gestational diabetes may face an increased risk of early heart disease later in life, even if they do not develop type 2 diabetes or metabolic syndrome subsequent to their pregnancy, according to a Kaiser Permanente study published today in the Journal of the American Heart Association.

13 Mar 2014

Higher levels of exposure to traffic-related air pollution linked to changes in right ventricle of the heart

Exposure to high levels of traffic-related air pollution is associated with changes in the right ventricle of the heart that may contribute to the known connection between air pollution exposure and heart disease, according to a new study.

7 Mar 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods.

5 Mar 2014

Noninvasive imaging with MRI of carotid artery plaque accurately predicts future cardiovascular events

Noninvasive imaging of carotid artery plaque with MRI can accurately predict future cardiovascular events like strokes and heart attacks in people without a history of cardiovascular disease, according to a new study published online in the journal Radiology.

4 Mar 2014

Blocking Netrin-1 in immune system stops chronic inflammation and insulin resistance tied to obesity

Researchers at NYU Langone Medical Center have found that blocking the action of a key signaling molecule in the immune system known as Netrin-1 stalls chronic inflammation and insulin resistance tied to obesity and often derived from fatty diets.

4 Mar 2014

Study finds significant reduction in hospital admissions with Medicare Part D prescription coverage

A new study by the Johns Hopkins Bloomberg School of Public Health and the University of Illinois at Chicago finds that Medicare Part D prescription coverage significantly reduced hospital admissions and program expenditures totaling $1.5 billion annually.

4 Mar 2014

Researchers analyze impact of chocolate consumption in vascular health

It might seem too good to be true, but dark chocolate is good for you and scientists now know why. Dark chocolate helps restore flexibility to arteries while also preventing white blood cells from sticking to the walls of blood vessels.

28 Feb 2014

Scientific Statement details latest evidence for diagnosis and treatment of fibromuscular dysplasia

A vascular disease called fibromuscular dysplasia, which can cause high blood pressure, kidney failure, stroke and other symptoms -- mostly in women -- is "poorly understood by many healthcare providers," according to a Scientific Statement from the American Heart Association.

27 Feb 2014

New scientific blood analysis predicts short-term mortality in humans

The general state of a person's metabolism can be diversely illustrated with a new scientific blood analysis. With the aid of the analysis biomarkers predicting short-term mortality have now been discovered

26 Feb 2014

Research roundup: Palliative care and ACOs; employers and Supreme Court case on contraception

In preparation for the new ACO environment, leaders recognized the contribution palliative care can make to health care "value," especially in the care of our sickest (and most expensive) patients ...

24 Feb 2014

Medicaid patients have longer lengths of stay for treatment of heart failure, shows study

Heart failure accounts for 6.5 million hospital days a year, and a new study reported in the Journal for Healthcare Quality showed that Medicaid patients and those with comorbid illnesses have longer lengths of stay for treatment of heart failure.

24 Feb 2014

New 256-slice CT scanner to predict potential heart attack in one second

What can you do in one second? Snap your fingers, blink your eyes, or get a diagnostic scan on a 256-slice computed tomography (CT) scanner? You can do all of those things in one second, but the one that may help save your life is the 256-slice CT scan.

21 Feb 2014

Exposure to common infections linked to memory and brain function

Exposure to common infections is linked to memory and brain function - even if the infections never made you ill, according to research presented at the American Stroke Association's International Stroke Conference 2014.

13 Feb 2014

Researchers develop multifunctional nanoparticle to pinpoint blood vessel plaques

A team of researchers, led by scientists at Case Western Reserve University, has developed a multifunctional nanoparticle that enables magnetic resonance imaging (MRI) to pinpoint blood vessel plaques caused by atherosclerosis.

7 Feb 2014

Atherosclerosis News and Research

Further Reading

Lower levels of vitamin D predict extent of coronary artery disease

TG2 protein is a key mediator in Porphyromonas gingivalis infection, study finds

Amgen announces results from Phase 3 TESLA Trial of evolocumab in patients with HoFH

Research on diverse health benefits of oats in protecting heart

Researchers create statistical model to predict whether heart scans are useful in prescribing statins

Researchers discover certain proteins in osteoclasts that may be used to destroy cardiovascular calcification

Women who experience gestational diabetes may face increased risk of heart disease later in life

Higher levels of exposure to traffic-related air pollution linked to changes in right ventricle of the heart

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Noninvasive imaging with MRI of carotid artery plaque accurately predicts future cardiovascular events

Blocking Netrin-1 in immune system stops chronic inflammation and insulin resistance tied to obesity

Study finds significant reduction in hospital admissions with Medicare Part D prescription coverage

Researchers analyze impact of chocolate consumption in vascular health

Scientific Statement details latest evidence for diagnosis and treatment of fibromuscular dysplasia

New scientific blood analysis predicts short-term mortality in humans

Research roundup: Palliative care and ACOs; employers and Supreme Court case on contraception

Medicaid patients have longer lengths of stay for treatment of heart failure, shows study

New 256-slice CT scanner to predict potential heart attack in one second

Exposure to common infections linked to memory and brain function

Researchers develop multifunctional nanoparticle to pinpoint blood vessel plaques

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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