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New drug shows promise in killing cancer cells with genetic vulnerability

Imagine the body's cells are well-behaved students in the classroom. The "teachers" are tumor suppressor genes, and they make sure cells follow the rules. But when tumor suppressor genes are away, cells may go astray.

1 Nov 2023

Study reveals direct link between high insulin levels and pancreatic cancer

A new study from researchers at the University of British Columbia's Faculty of Medicine reveals a direct link between high insulin levels, common among patients with obesity and Type 2 diabetes, and pancreatic cancer.

31 Oct 2023

New antibody may offer effective drug treatment for breast cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks.

30 Oct 2023

Short-chain fatty acids produced by intestinal bacteria play role in dendritic cell elongation

Dendritic cells play a key role in the mammalian immune system. These cells are present throughout the human body and are known to capture foreign bodies, i.e., antigens, using extendable "arms" called dendrites.

30 Oct 2023

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

Researchers found that SARS-CoV-2 antigens can persist in the body for up to 14 months after initial infection, challenging the idea that COVID-19 is a transient illness. This finding has implications for understanding long-term effects of the virus and could influence future treatments and vaccines.

30 Oct 2023

Researchers receive €10.6 million to develop new therapeutic approaches to target glioblastoma

Researchers at the Universities of Amsterdam and Leiden together with the Netherlands Cancer Institute (Amsterdam) and Oncode Institute (Utrecht) have received a €10.6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma, a deadly primary brain tumor for which no curing therapy is yet available.

26 Oct 2023

In acute myocardial infarction patients, does adding a traditional Chinese medicine compound to standard treatments improve outcomes?

Researchers investigated whether Tongxinluo, a Chinese medicinal compound, could improve clinical outcomes among ST-segment elevation myocardial infarction patients.

26 Oct 2023

Stanford chemists uncover new pathway for protein degradation, opening door to new therapeutics

When targeting problem proteins involved in causing or spreading disease, a drug will often clog up a protein's active site so it can't function and wreak havoc.

25 Oct 2023

NF-κB activation during COVID-19 and its impact on patients with hypertension

Researchers review the role of NF-κB activation in the replication of SARS-CoV-2 and the impact of COVID-19 medications on NF-κB activation.

25 Oct 2023

BA.2.86 Omicron sub-variant shows high receptor affinity but moderate neutralization resistance

Study investigates the receptor affinity and antigenicity of the SARS-CoV-2 Omicron BA.2.86 variant, revealing that it does not show higher resistance to neutralization by human sera than other recent variants. Despite its high number of mutations and receptor affinity, the variant is slightly more sensitive to neutralization than the EG.5.1 variant, warranting continued surveillance.

24 Oct 2023

Community immunity: Steering the evolutionary course of SARS-CoV-2

Researchers in Germany have developed a comprehensive fitness model that forecasts the evolution of SARS-CoV-2 by integrating genetic, epidemiological, and immunological data. The study emphasizes the role of population immunity in shaping viral mutations and provides valuable insights into the emergence of new variants.

24 Oct 2023

Engineered bacteria could offer new treatment for hypertension

Scientists at The University of Toledo have proven that engineered bacteria can lower blood pressure, a finding that opens new doors in the pursuit of harnessing our body's own microbiome to treat hypertension.

24 Oct 2023

Utilizing Biomarkers in Cancer Prevention, Diagnosis, and Treatment

In this interview, Grace Liu from Sino Biological discusses the crucial role of biomarkers in cancer prevention and diagnosis and how they can help guide treatment decisions.

From Sino Biological Inc. 24 Oct 2023

Intranasal vaccination: A potent one-time solution for comprehensive COVID-19 immunity

A single-dose intranasal vaccine effectively induces robust immune responses.

24 Oct 2023

Is COVID-19 a risk factor for Alzheimer's disease?

The study explores the interconnected risks between COVID-19 and Alzheimer's Disease (AD), highlighting how SARS-CoV-2 can aggravate AD pathology through neuroinflammation and neurodegeneration. It raises significant concerns about the long-term cognitive implications of COVID-19, especially among those already at risk for AD.

23 Oct 2023

COVID-19 tied to elevated risk of benign prostatic hyperplasia complications

SARS-CoV-2 infection linked to increased benign prostatic hyperplasia (BPH) complications and medication use. Urological manifestations in COVID-19 patients emphasize the importance of awareness among clinicians.

22 Oct 2023

Hormone levels tied to metabolic health in obesity

Researchers investigate the relationship between obesity types and serum leptin (LEP) and adiponectin (ADP) levels, shedding light on metabolic differences in various obesity phenotypes. Their findings highlight correlations between adipokines, glucose utilization, lipid metabolism, and obesity-related metabolic disorders.

22 Oct 2023

Enzyme News and Research

New drug shows promise in killing cancer cells with genetic vulnerability

Study reveals direct link between high insulin levels and pancreatic cancer

New antibody may offer effective drug treatment for breast cancer

Short-chain fatty acids produced by intestinal bacteria play role in dendritic cell elongation

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

Researchers receive €10.6 million to develop new therapeutic approaches to target glioblastoma

In acute myocardial infarction patients, does adding a traditional Chinese medicine compound to standard treatments improve outcomes?

Stanford chemists uncover new pathway for protein degradation, opening door to new therapeutics

NF-κB activation during COVID-19 and its impact on patients with hypertension

BA.2.86 Omicron sub-variant shows high receptor affinity but moderate neutralization resistance

Community immunity: Steering the evolutionary course of SARS-CoV-2

Engineered bacteria could offer new treatment for hypertension

Utilizing Biomarkers in Cancer Prevention, Diagnosis, and Treatment

Intranasal vaccination: A potent one-time solution for comprehensive COVID-19 immunity

Is COVID-19 a risk factor for Alzheimer's disease?

COVID-19 tied to elevated risk of benign prostatic hyperplasia complications

Hormone levels tied to metabolic health in obesity

Canine transmission models provide insights into the neurological impacts of COVID-19 on human brains

Low serotonin levels observed in long COVID and other viral infections

Virginia Tech researchers develop new drug design framework to fight COVID-19

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

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