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Dopamine treatment can reduce Alzheimer's plaques and improve memory

A new way to combat Alzheimer's disease has been discovered by Takaomi Saido and his team at the RIKEN Center for Brain Science (CBS) in Japan.

6 Aug 2024

New dual-purpose contrast agent revolutionizes PET and MRI integration for enhanced diagnosis

A research team from IOCB Prague, working in collaboration with the University of Tübingen, Germany, and the Faculty of Science, Charles University, has developed a new type of contrast agent that can be used in both magnetic resonance imaging (MRI) and positron emission tomography (PET).

5 Aug 2024

Cannabigerol shows promise in reducing anxiety and stress, study finds

Whether the phytocannabinoid cannabigerol impacted mood, stress, and anxiety and caused any related adverse effects of cognitive or motor impairment.

5 Aug 2024

Novel antibiotic compound shows promise against drug-resistant bacteria and flesh-eating infections

Researchers at Washington University School of Medicine in St. Louis have developed a novel compound that effectively clears bacterial infections in mice, including those that can result in rare but potentially fatal "flesh-eating" illnesses.

2 Aug 2024

How machine learning is accelerating research in structural biology

For Lucas Farnung, there is no question more fascinating than how a single fertilized egg develops into a fully-functioning human.

2 Aug 2024

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first approved in 2017 in the USA and a year later in Europe for treating acute lymphoblastic leukemia (ALL).

2 Aug 2024

Researchers identify strategy to design safer opioids

Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose.

2 Aug 2024

Single-cell RNA sequencing sheds light on stroke-induced brain damage

Strokes lead to irreversible damage to the brain and are one of the most common causes of dependency or death.

1 Aug 2024

Researchers develop highly reactive RNA building blocks for enhanced chip production

An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient. The results of the research were recently published in the prestigious journal Science Advances.

1 Aug 2024

Scientists capture NMDAR protein's 'twist' motion, key to brain signaling

Proteins are constantly performing a kind of dance. They move and contort their bodies to fulfill specific functions inside our bodies. The NMDAR protein executes an especially hard dance routine in our brains. One wrong step can lead to a range of neurological disorders. NMDAR binds to the neurotransmitter, glutamate, and another compound, glycine. These bindings control NMDAR's dance steps. When their routine is over, the NMDAR opens. This open ion channel generates electrical signals critical for cognitive functions like memory.

1 Aug 2024

Research uncovers mechanism behind diaphragm weakness during mechanical ventilation in ICU patients

Researchers from Amsterdam UMC have found a new mechanism explaining diaphragm weakness that arises during mechanical ventilation in the intensive care unit. The diaphragm is the most important breathing muscle.

31 Jul 2024

New discovery unveils key process in DNA repair pathway

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of Molecular Biology (LMB) in Cambridge, has solved a decades-old mystery which could pave the way to better cancer treatments in the future.

31 Jul 2024

Exosome-encapsulated fluorescent sensors enable advanced brain imaging in Alzheimer's research

Neurotransmitter levels in the brain can indicate brain health and neurodegenerative diseases like Alzheimer's.

31 Jul 2024

Quantum simulation drives breakthrough in drug development

Led by University of Melbourne theoretician and HPC expert Associate Professor Giuseppe Barca, a research team has achieved the first quantum simulation of biological systems at a scale necessary to accurately model drug performance.

31 Jul 2024

Study finds higher levels of lncRNAs in the testes than previously estimated

Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes.

30 Jul 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

Maternal immune response to flu linked to fetal brain changes

A bad case of the flu during pregnancy can increase the risk for fetal neurodevelopmental disorders such as schizophrenia and autism spectrum disorder. But it's not the virus itself doing the damage; it's the mother's immune response.

29 Jul 2024

New dual kinase inhibitor MTX-531 shows promise in overcoming cancer therapy resistance

A team of researchers at the University of Michigan Health Rogel Cancer Center has designed a molecule that impairs signaling mediated by two key drivers of cancer therapy resistance.

29 Jul 2024

PUFA metabolites in umbilical cord blood may predict autism spectrum disorder

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects learning capability and social behavior of people.

29 Jul 2024

Overcoming cancer relapse with CAR-Enhancer therapy

Even as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant limitation: many patients, including those whose cancer goes into full remission, eventually relapse. In a new study, Dana-Farber Cancer Institute researchers report on a technique with the potential to eliminate that problem.

29 Jul 2024