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Sphingotec reports new applications of bio-ADM at 39th ISICEM

Diagnostics company sphingotec GmbH reports novel applications of bio-ADM, the very first biomarker capable to diagnose the onset of septic shock, allowing physicians earliest life-saving therapeutic interventions in sepsis critical care.

20 Mar 2019

Premature babies also have protective anti-viral antibodies

Even premature babies carry anti-viral antibodies transferred from the mother, researchers at Karolinska Institutet in Sweden report in a paper on maternal antibodies in newborns, published in the journal Nature Medicine.

18 Mar 2019

Long-awaited structure offers new insights into rejection of transplanted organs

Rejection of any kind is always hard to deal with, but when one's body rejects a precious organ transplant, the consequences can be devastating. Professor A. Vathsala, Co-director of the National University Centre for Organ Transplantation at the National University Hospital and Professor of Medicine, shared that between 30% to 40% of kidney transplants are lost over time to rejection.

15 Mar 2019

Study uncovers potential new strategy to treat influenza A

A team of researchers from Scripps Research and Janssen Research & Development LLC has discovered an orally active small molecule that neutralizes influenza A group 1 viruses, the most common flu strains.

11 Mar 2019

Researchers identify gene that increases risk of antibiotic reaction

Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

11 Mar 2019

Researchers elucidate how embryonic cells and tissues respond to force

Accumulated evidence suggests that physical force plays an important role in various developmental processes of fertilized animal eggs.

8 Mar 2019

Peptide derived from fungi prevents growth of tuberculosis bacteria

The discovery of the peptide as a possible future antibiotic was made when the researchers screened different antimicrobial peptides' ability to prevent the growth of the tuberculosis bacteria Mycobacterium tuberculosis.

4 Mar 2019

Engineer to develop drug-filled hydrogel to repair the damaged heart

After a heart attack, the cells in the heart muscle cannot get enough nutrients and oxygen to survive, so they die. A structural support network in the heart's wall can help those cells regenerate, however, two enzymes that break down the network are naturally increased after a heart attack, leaving the heart in a fight for its life.

28 Feb 2019

Personalized therapy for aggressive brain cancer shows potential

Advances in genetics and genomics have taught us that every single tumor is different, and yet most standard therapies treat them all in the same way, limiting the effectiveness of treatments offered to many cancer patients.

28 Feb 2019

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses.

26 Feb 2019

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Researchers have engineered "antibody-like" T cell receptors that can specifically stick to cells infected with cytomegalovirus, or CMV, a virus that causes lifelong infection in more than half of all adults by age 40.

23 Feb 2019

New design guidance could advance development of disease-sensing nanomaterials

Scientists have long sought to develop drug therapies that can more precisely diagnose, target and effectively treat life-threatening illness such as cancer, cardiovascular and autoimmune diseases.

22 Feb 2019

Researchers study animal venoms to identify new medicines for treating diseases

Animal venoms are the subject of study at research center based at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets of diseases and, armed with that knowledge, develop new compounds that can be used as medicines.

15 Feb 2019

Platinum nanoparticles show selective toxicity against liver cancer cells

In recent years, the number of targeted cancer drugs has continued to rise. However, conventional chemotherapeutic agents still play an important role in cancer treatment.

15 Feb 2019

Researchers discover mechanism on how body's antimicrobial shield regulates microbiome

The microbiome in our intestine plays a vital role in people's health and the immune system. Any lack of balance there has not only been linked to chronic inflammatory intestinal inflammation, but also type 2 diabetes and other diseases

12 Feb 2019

Bariatric surgery changes the way our body senses food

How bariatric surgery helps people with obesity and diabetes is related to changes in the way the gut senses food and nutrients after the operation, researchers report February 5 in the journal Cell Reports.

8 Feb 2019

Cloning-free Nested CRISPR uses long DNA fragments for efficient gene editing

CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. However, even though it allows the creation or correction of mutations consisting of a single or few nucleotides with relative ease, it still possesses limitations upon introducing larger fragments of DNA in the genome.

8 Feb 2019