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$Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers$

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Patients with treatment-refractory cancers who received eligibility and testing waivers to participate in a large basket/umbrella oncology trial had similar rates of clinical benefit and adverse events as patients who participated in the trial without waivers.

27 Jun 2024

Amorphous calcium phosphate drives aortic valve stiffening

The human body has sophisticated defenses against the deposition of calcium minerals that stiffen heart tissues, researchers at the University of Illinois Urbana-Champaign and collaborators at UCLA Health and the University of Texas at Austin found in a new study that provides the first detailed, step-by-step documentation of how calcification progresses.

27 Jun 2024

Evaluating CGM accuracy and benefits in non-diabetic populations

A new narrative review led by researchers at UCL and Birmingham Children's Hospital has found there is a lack of evidence to demonstrate the effective use of continuous glucose monitors (CGMs) in people not living with diabetes (PNLD).

27 Jun 2024

California’s $25 health care hourly wage relies on federal boost, state worker exemption

California's nation-leading $25 minimum wage for health workers will rely on a significant boost in federal funding and exempt thousands of state employees under an agreement that is expected to be approved in the coming days.

26 Jun 2024

Dietary fiber promotes beneficial conversion of tryptophan by gut bacteria

We get healthy dietary fibres from consuming fruits, vegetables, and whole grains. But why are the fibres so good for us? A team of researchers has discovered that dietary fibres play a crucial role in determining the balance between the production of healthy and harmful substances by influencing the behavior of bacteria in the colon.

26 Jun 2024

Research finds increased cancer risk in diabetic adults aged 40-54 years

Diabetes significantly increases the risk of cancer, particularly in people aged 40-54 years, new research shows.

26 Jun 2024

Hospital-based donor care linked to longer lung transplant survival rates

A new study by Penn researchers examined, for the first time, the differences in lung transplant graft outcomes from organs recovered from the two types of deceased organ donor care facilities operating in the United States. The research, published today in JAMA Network Open, offers insights that could improve the organ donation and transplantation process for patients across the nation.

26 Jun 2024

Semaglutide proves a game-changer for kidney and heart health in diabetes patients

The FLOW trial demonstrated that semaglutide significantly improves kidney and cardiovascular outcomes in people with chronic kidney disease and type 2 diabetes, irrespective of SGLT2 inhibitor use.

25 Jun 2024

Innovative insulin algorithm enhances glucose control for hospitalized patients

Hospitalized patients with complex dietary restrictions often develop hyperglycemia, or high blood sugar.

25 Jun 2024

Breakthrough biomarker predicts recurrence risk in clear cell renal cancer

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a biomarker that could help identify which renal cancer patients have a higher risk of recurrence.

25 Jun 2024

Using real-world data to assess medication-related liver toxicity

The current method for assessing medication-related liver injury is not providing an accurate picture of some medications' toxicity - or lack thereof - to the liver, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

25 Jun 2024

MicroRNAs shed light on aggressive youthful type 2 diabetes

Type 2 diabetes in young people ages 10 to19 has more than doubled in the past 20 years, yet it remains difficult for physicians to predict who will be diagnosed and who will improve with treatment. A newly published study from the University of Oklahoma shows that measuring the circulating abundance of microRNAs – which affect insulin-producing beta cells in the pancreas – is likely as effective as measuring the level of sugar in the blood for determining how a young person with the condition will fare.

25 Jun 2024

WEHI study reveals new methods in detecting necroptosis

Fully automated diagnostic techniques, including liquid handling robots, are poised to improve the lives of millions of people living with inflammatory diseases worldwide.

24 Jun 2024

It’s called an urgent care emergency center — but which is it?

One evening last December, Tieqiao Zhang felt severe stomach pain.

24 Jun 2024

Novo Nordisk presents key findings from semaglutide trials at ADA scientific sessions 2024

Novo Nordisk today announced the presentation of 34 abstracts highlighting the breadth of its portfolio at the upcoming 84th Scientific Sessions of the American Diabetes Association (ADA).

22 Jun 2024

Expert orthopedic surgeon saves man’s leg from being amputated after damage from advanced cancer

Richard Monti, a father of six and a real estate developer on Long Island, thought that his metastatic kidney cancer diagnosis would be the toughest battle to endure in his life.

21 Jun 2024

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries - small blood vessels that regulate the movement of ions, water, and metabolites while maintaining impermeability to essential macromolecules such as proteins.

21 Jun 2024

3D-printed wearable health monitor tracks biochemicals in sweat

A wearable health monitor developed by Washington State University researchers can reliably measure levels of important biochemicals in sweat during physical exercise.

20 Jun 2024

New WHO classification of kidney tumors integrates molecular diagnostics

Renal tumor pathology has evolved considerably, expanding from two main types of renal malignant tumors to over 20 distinct types.

18 Jun 2024

New research on long COVID prevalence and risk factors

Early in the pandemic, many people who had SARS-Cov-2 infection or COVID-19 began to report that they couldn't shake off their symptoms even after a month or more - unusually long for a viral infection of the upper respiratory tract - or developed new, persistent symptoms soon after the infection cleared.

18 Jun 2024