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Investigational cancer vaccine shows early promise for cancer prevention in Lynch syndrome

The investigational cancer vaccine, NOUS-209, was found to safely stimulate the immune system to target precancerous and cancerous cells in individuals with Lynch Syndrome (LS), according to a study from researchers at The University of Texas MD Anderson Cancer Center.

16 Jan 2026

Study tests combined targeted radiopharmaceuticals and precision radiation for recurrent prostate cancer

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have opened a clinical trial that will look at whether combining precision radiation with a targeted radioactive therapy drug can help patients with recurrent prostate cancer delay progression, while delaying or avoiding the side effects of long-term hormone therapy.

16 Jan 2026

Monolithic photocurable hyaluronic acid patch achieves strong wet adhesion for durotomy repair

Durotomy is a common neurosurgical complication involving a tear in the dura mater, the protective membrane surrounding the brain and spinal cord.

16 Jan 2026

Study provides a new paradigm for managing transplant‑related immune complications

Acute graft-versus-host disease (aGVHD) is one of the most serious complications after allogeneic hematopoietic stem cell transplantation (allo‑HSCT).

16 Jan 2026

Targeting microRNA communication reverses pancreatic cancer's immune suppression

In a unique finding, researchers at Georgetown's Lombardi Comprehensive Cancer Center discovered that when pancreatic cancer cells send out tiny particles that are packed with certain microRNA molecules, nearby immune cells called macrophages are reprogrammed to help the tumor grow instead of engaging in their regular role of fighting the tumor.

16 Jan 2026

Cancer mortality drops 34% as treatments and early detection improve

The 2026 cancer statistics reveal improved survival rates but highlight persistent inequities in cancer incidence and mortality across different populations.

16 Jan 2026

What makes a run feel great or terrible, according to runners themselves

A qualitative analysis of Strava data highlights the impact of environment and social interactions on runner sentiment and mental health during the pandemic.

16 Jan 2026

Smoking cessation apps can boost quit rates, especially alongside medication

Smartphone apps show promise in smoking cessation, outperforming minimal support and enhancing traditional interventions, according to a recent meta-analysis.

16 Jan 2026

As insurance prices rise, families puzzle over options

New York-based performer Cynthia Freeman, 61, has been trying to figure out how to keep the Affordable Care Act health plan that she and her husband depend on.

16 Jan 2026

Vagus nerve stimulation shows lasting benefit in treatment-resistant depression

Findings reveal that vagus nerve stimulation leads to lasting benefits in treatment-resistant depression, improving function and quality of life over two years.

16 Jan 2026

Bio-engineered skin grafts offer new hope for severe burn injuries

Bio-engineered skin grafts can play an important role in the treatment of burn victims. Researchers at the University of Zurich have been working on new approaches for such grafts for over 15 years.

15 Jan 2026

Repurposed Alzheimer’s medication offers low-cost hope for sickle cell anemia

Sickle cell anemia is the world's most common genetic disorder. It causes the red blood pigment hemoglobin to crystallize, which results in rigid, malformed red blood cells with a sickle shape.

15 Jan 2026

Immune dysfunction persists after combined TB and HIV therapy

The immune system remains seriously out-of-whack – in an inflammatory state of overactivation and impaired functionality – following the international gold standard for treating people with latent tuberculosis (TB) and HIV, a team at Texas Biomedical Research Institute reports in Nature Communications.

14 Jan 2026

Scientists reveal how cholera bacteria activate toxin genes in the human gut

Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of deaths reported worldwide each year.

14 Jan 2026

Bacterial metabolite enhances immune checkpoint therapy against lung cancer

UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.

14 Jan 2026

Phase II clinical trial shows promising results for novel sepsis drug

Griffith University researchers may have unlocked the secret to treating sepsis, with a Phase II clinical trial in China successfully concluding with promising results.

14 Jan 2026

Study reveals genetic signatures linked to HIV-related cognitive impairment

Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled.

14 Jan 2026

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid deposits of misfolded transthyretin (TTR) proteins.

14 Jan 2026

Lund researchers create "recipe book" for reprogramming immune cells to fight disease

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation.

14 Jan 2026

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

Nitin Joshi, PhD, and Jingjing Gao, PhD, of the Department of Anesthesiology at Mass General Brigham, are the co-senior authors of a paper published in Nature Nanotechnology, "A disease-severity-responsive nanoparticle enables potent ghrelin mRNA therapy in osteoarthritis." Mahima Dewani, PhD, is the lead author of this study.

14 Jan 2026

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Therapy News and Research

Investigational cancer vaccine shows early promise for cancer prevention in Lynch syndrome

Study tests combined targeted radiopharmaceuticals and precision radiation for recurrent prostate cancer

Monolithic photocurable hyaluronic acid patch achieves strong wet adhesion for durotomy repair

Study provides a new paradigm for managing transplant‑related immune complications

Targeting microRNA communication reverses pancreatic cancer's immune suppression

Cancer mortality drops 34% as treatments and early detection improve

What makes a run feel great or terrible, according to runners themselves

Smoking cessation apps can boost quit rates, especially alongside medication

As insurance prices rise, families puzzle over options

Vagus nerve stimulation shows lasting benefit in treatment-resistant depression

Bio-engineered skin grafts offer new hope for severe burn injuries

Repurposed Alzheimer’s medication offers low-cost hope for sickle cell anemia

Immune dysfunction persists after combined TB and HIV therapy

Scientists reveal how cholera bacteria activate toxin genes in the human gut

Bacterial metabolite enhances immune checkpoint therapy against lung cancer

Phase II clinical trial shows promising results for novel sepsis drug

Study reveals genetic signatures linked to HIV-related cognitive impairment

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Lund researchers create "recipe book" for reprogramming immune cells to fight disease

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

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