Protein C News and Research

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Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

"Do not erase." "Recycle me." "Free to a good home." Humans post these signs to indicate whether something has value or not, whether it should be disposed of or not.

18 Sep 2020

Molecular imaging probe reveals Alzheimer's-related γ-secretase in rodents, macaques

Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer's disease (AD)-related γ-secretase in rodents and macaques with translational potentials in humans.

18 Sep 2020

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

Psychedelic drugs such as LSD, psilocybin, and mescaline cause severe and often long-lasting hallucinations, but they show great potential in treating serious psychiatric conditions, such as major depressive disorder.

18 Sep 2020

Study sheds new light on the mechanism of COVID-19 infection

The spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor ACE2, according to research from the Francis Crick Institute published in Nature today.

18 Sep 2020

Researchers describe details of protein linked to genetically inherited Parkinson's disease

In August, a team of researchers at the University of California San Diego published groundbreaking back-to-back studies describing unprecedented details of a protein linked to genetically inherited Parkinson's disease.

18 Sep 2020

Engineered, high-affinity ACE2 receptors neutralize SARS-CoV-2

In a study published in the preprint server bioRxiv, researchers from the Kyoto Prefectural University of Medicine and Osaka University Japan, discuss how they engineered ACE2 to enhance its affinity to RBD in human cells.

17 Sep 2020

Blood protein test could detect severity of head trauma in minutes

A blood protein test could detect the severity of head trauma in under 15 minutes, according to research published recently in the Journal of Neurotrauma.

17 Sep 2020

Researchers identify cause for thrombosis in COVID-19 patients

A new University of Kentucky College of Medicine study may provide answers for why so many COVID-19 patients experience thrombosis, or the formation of blood clots that obstruct blood flow through the circulatory system.

17 Sep 2020

Glucagon resistance: A new biological concept in the fight against diabetes

Researchers from the University of Copenhagen are introducing a new biological concept in the fight against diabetes: glucagon resistance.

17 Sep 2020

Biomarker predicts disease severity in COVID-19 patients

Airway cell analyses showing an activated immune axis could pinpoint the COVID-19 patients who will most benefit from targeted therapies.

17 Sep 2020

New drug candidate suppresses SARS-CoV-2 replication

Researchers at Stanford University and Utah State University have developed a novel inhibitor of the coronavirus main protease (Mpro) that effectively suppresses the viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Flexibility of glycosylated membrane-bound ACE2 suggests mechanical energy source in opening of SARS-CoV-2 spike

Angiotensin, Angiotensin-Converting Enzyme 2, Cell, Coronavirus, Enzyme, Glycoprotein, Neck, Protein, Receptor, Respiratory, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Syndrome, Virus, SARS-CoV-2, Coronavirus Disease COVID-19,

17 Sep 2020

Could pineapples be a new weapon against COVID-19?

Results of a recent research endeavor from the United States indicate that bromelain or bromelain rich pineapple stem may be utilized as an antiviral agent against coronavirus disease (COVID-19), but also for potential future coronavirus outbreaks. This exciting paper is currently available on the bioRxiv preprint server.

17 Sep 2020

CNIC researchers uncover a mechanism explaining how macrophages regulate obesity

Macrophages are immune system cells. They are essential in the early response to infections, and they also have a key role in the proper functioning of our tissues and the regulation of obesity.

17 Sep 2020

Breadfruit flour found to be a healthy alternative to other starches for modern foods

A fruit used for centuries in countries around the world is getting the nutritional thumbs-up from a team of British Columbia researchers.

17 Sep 2020

Scientists identify new genetic cause of syndromic microcephaly

Greenwood Genetic Center researchers, in collaboration with scientists from Belgium, Spain, and Italy, have confirmed that variants in LMNB1 cause syndromic microcephaly with variable short stature, intellectual disability, and other neurological symptoms.

17 Sep 2020

Combined use of three drugs linked with lower lung cancer incidence and mortality

Combined use of aspirin, statins, and metformin is associated with decreased lung cancer incidence and mortality, according to a study published in the Journal of Thoracic Oncology.

17 Sep 2020

UTHSC professor receives $455,000 grant to study cause of aggressive prostate cancer

Ramesh Narayanan, PhD, professor in the Department of Medicine and the Division of Hematology and Oncology at the University of Tennessee Health Science Center, has received a $455,000 grant from the National Cancer Institute for a two-year study of the underlying cause of the development of aggressive prostate cancer in African American men.

17 Sep 2020

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

After screening more than 3,500 FDA-approved drugs and small molecules, researchers at the Chinese Academy of Sciences found that ceftazidime, an antibiotic approved for use in treating pneumonia, binds to the receptors that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to in human cells.

17 Sep 2020

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

A recent study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University and published on the preprint server bioRxiv in September 2020 shows that a combination of neutralizing antibodies with intact Fc effector function can effectively reduce the viral load and prevent infection.

17 Sep 2020

Protein C News and Research

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

Molecular imaging probe reveals Alzheimer's-related γ-secretase in rodents, macaques

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

Study sheds new light on the mechanism of COVID-19 infection

Researchers describe details of protein linked to genetically inherited Parkinson's disease

Engineered, high-affinity ACE2 receptors neutralize SARS-CoV-2

Blood protein test could detect severity of head trauma in minutes

Researchers identify cause for thrombosis in COVID-19 patients

Glucagon resistance: A new biological concept in the fight against diabetes

Biomarker predicts disease severity in COVID-19 patients

New drug candidate suppresses SARS-CoV-2 replication

Flexibility of glycosylated membrane-bound ACE2 suggests mechanical energy source in opening of SARS-CoV-2 spike

Could pineapples be a new weapon against COVID-19?

CNIC researchers uncover a mechanism explaining how macrophages regulate obesity

Breadfruit flour found to be a healthy alternative to other starches for modern foods

Scientists identify new genetic cause of syndromic microcephaly

Combined use of three drugs linked with lower lung cancer incidence and mortality

UTHSC professor receives $455,000 grant to study cause of aggressive prostate cancer

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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