Protein C News and Research

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Newly designed hydrogels allow the culture of T-cells for use in cancer immunotherapy

A team with the participation of researchers from the Spanish National Research Council has designed new hydrogels that allow the culture of T-cells or T-lymphocytes, cells of the immune system that are used in cancer immunotherapy since they have the capacity to destroy tumor cells.

31 Aug 2020

Study identifies effective treatment for severe COVID-19 patients

As countries around the world race to develop a vaccine for SARS-CoV-2, the virus responsible for COVID-19, researchers are working to understand exactly how it causes the myriad of symptoms that seem to linger long after active viral infection.

31 Aug 2020

Food system transformation may require an unprecedented level of global cooperation

"Food systems have the potential to nurture human health and support environmental sustainability; however, they are currently threatening both." This sentence, the opening statement of the EAT-Lancet Report published last year, reflects a growing consensus among global experts on food, nutrition and the environment: Our food system is broken and we need to fix it, fast.

31 Aug 2020

Study examines whether asthma is a significant risk factor for severe COVID-19

A new research letter published online in the Annals of the American Thoracic Society examines whether asthma is a significant risk factor for developing COVID-19 that is severe enough to warrant hospitalization and intubation.

31 Aug 2020

T cell epitopes from recovered COVID-19 patients identified for vaccine

A new study by researchers at The Hong Kong University of Science and Technology and published on the preprint server bioRxiv in August 2020 collates the available database of SARS-CoV-2 T cell epitopes gathered from 8 studies of COVID-19 patients who recovered. This could serve as a launchpad to fill in knowledge gaps regarding the immunological aspects of this disease, and drive towards an effective T cell vaccine.

31 Aug 2020

IL-6 signaling blockade can alleviate severe COVID-19

A team of researchers led by Osaka University find an overlap in the pathogenesis of cytokine release syndrome and COVID-19, and show that the symptoms of both can be alleviated by IL-6 signaling blockade

31 Aug 2020

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Now, a team of researchers at the University of Alberta in Canada has identified viral inhibitors that they claim are potential candidates as a treatment for COVID-19. The team is set to launch clinical trials of the drug that is used as a treatment for a type of coronavirus in cats.

31 Aug 2020

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Cardiovascular disease is the leading cause of death in humans. Worldwide, as the population ages, the burden of treating heart failure is increasing; opportunities for heart transplantation cannot keep pace.

31 Aug 2020

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

A new study published on the preprint server bioRxiv* in August 2020 reports the disease-mitigating effects of a serum protein called serum amyloid P (SAP) in mice exposed to a peptide that mimics the clinical signs of severe COVID-19 in humans.

30 Aug 2020

Using SARS-CoV-2 epitope to construct a vaccine

A new study published on the preprint server bioRxiv* in August 2020 reports the use of prediction and advanced simulation techniques to identify a novel T cell epitope on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could serve as the basis for a customized vaccine with broad-based efficacy.

30 Aug 2020

SARS-CoV-2 Neucleocapside (N) protein is heavily glycosylated

However, the nucleocapsid (N) protein is also extremely abundant and, therefore, a useful target for both vaccine and diagnostic test development. A new study published on the preprint server bioRxiv in August 2020 reveals the structure of this protein, a valuable step in using it for these purposes.

30 Aug 2020

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Researchers from Sechenov University together with Russian and Iranian colleagues described currently known approaches to the treatment of SARS-CoV-2 infection.

29 Aug 2020

Study may help explain the symptoms and organs involved with SARS-CoV-2 infection

A study of a gateway receptor for SARS-CoV-2 led by Walter Lukiw, PhD, Professor of Neuroscience, Neurology and Ophthalmology at LSU Health New Orleans' Neuroscience Center of Excellence and School of Medicine, may help explain the wide variety of symptoms and organs involved with SARS-CoV-2 infection and COVID-19.

28 Aug 2020

Exploring the structure and dynamics of biological nanomachine

A small but important step towards a successful immune reaction is performed by an impressive nanomachine. Researchers use simulations to understand how it works.

28 Aug 2020

New method can help develop drugs that target membrane proteins

Portland State University researchers used advanced electron microscopy to create a 3-D reconstruction of a membrane protein at an unprecedented level of resolution, setting the stage for the development of drugs that could target the protein more effectively to treat a variety of diseases.

28 Aug 2020

Researchers reveal how bacteria adhere to cellulose fibers in the gut

Researchers have revealed a new molecular mechanism by which bacteria adhere to cellulose fibers in the human gut. Thanks to two different binding modes, they can withstand the shear forces in the body.

28 Aug 2020

CNOT3 protein plays a key role in diabetes

A protein that's common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit at the Okinawa Institute of Science and Technology Graduate University and Riken Center of Integrative Medical Sciences.

28 Aug 2020

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Alberto Yáñez Boyer, Ramón y Cajal researcher at BIOTECMED (Interdisciplinary Research Structure in Biotechnology and Biomedicine) and the Department of Microbiology and Ecology at the University of Valencia (UV), participates in a study on the C9orf72 gene and its mutations in the immune system.

28 Aug 2020

Researchers develop advanced imaging technique to visualize effects of valencies on B cell responses

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

DNA structure is determined by spatial rules based on specific protein sequences and their order

DNA three-dimensional structure is determined by a series of spatial rules based on particular protein sequences and their order.

28 Aug 2020

Protein C News and Research

Newly designed hydrogels allow the culture of T-cells for use in cancer immunotherapy

Study identifies effective treatment for severe COVID-19 patients

Food system transformation may require an unprecedented level of global cooperation

Study examines whether asthma is a significant risk factor for severe COVID-19

T cell epitopes from recovered COVID-19 patients identified for vaccine

IL-6 signaling blockade can alleviate severe COVID-19

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

Using SARS-CoV-2 epitope to construct a vaccine

SARS-CoV-2 Neucleocapside (N) protein is heavily glycosylated

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Study may help explain the symptoms and organs involved with SARS-CoV-2 infection

Exploring the structure and dynamics of biological nanomachine

New method can help develop drugs that target membrane proteins

Researchers reveal how bacteria adhere to cellulose fibers in the gut

CNOT3 protein plays a key role in diabetes

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Researchers develop advanced imaging technique to visualize effects of valencies on B cell responses

DNA structure is determined by spatial rules based on specific protein sequences and their order

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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