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Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Researchers at Osaka University identify vicious cycle involving RNA exosome that accelerates disease progression in FTLD/ALS

24 Aug 2020

Bio-Helix announces approved patent for ECL

Bio-Helix is pleased to be notified of the approved patent application for its proprietary enhanced chemiluminescent substrates (ECL).

24 Aug 2020

Study reveals a promising method for treating multiple sclerosis

A research team led by neurobiologist Professor Claire Jacob has identified an important mechanism that can be used to control the restoration of myelin sheaths following traumatic injury and in degenerative diseases.

24 Aug 2020

Study examines the effects of cancer and its treatment on aging process

A new study examines the effects of cancer and its treatment on the aging process. Investigators found that expression of a gene associated with aging is higher in young patients with cancer after treatment with chemotherapy and in young cancer survivors who are frail.

24 Aug 2020

Study: Fewer types of fungi in the lungs are associated with increased severity of disease in ARDS patients

Many COVID-19 patients develop acute respiratory distress syndrome (ARDS), a life-threatening condition where the lungs cannot provide the body's vital organs with enough oxygen.

24 Aug 2020

FDA issues emergency use authorization for convalescent plasma in COVID-19

The FDA said that based on the scientific evidence available, it had released a decision memorandum that convalescent plasma may be useful in treating COVID-19 in hospitalized patients, and the known potential benefits of use outweigh the risks.

24 Aug 2020

Loss of supporting cells in olfactory epithelium causes loss of smell in COVID-19

In the current pandemic of COVID-19, many patients have reported symptoms of loss of smell and taste. The cellular basis of this phenomenon has not been satisfactorily explained so far. However, a new study published in the Briefings in Bioinformatics in August 2020 shows how this symptom is related to viral pathogenesis.

23 Aug 2020

Equine antibody preparation shows greater capacity to neutralize SARS-CoV-2 isolate than human convalescent plasma

A recent Brazilian study demonstrates that hyperimmune globulin formulations generated against the recombinant spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provide significantly high antibody titer with highly neutralizing capacity. The study is currently available on the bioRxiv preprint server.

23 Aug 2020

Pfizer/BioNTech COVID-19 vaccine candidate BNT162b2 profiled for large scale clinical trials

Although two RNA-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates elicited similar, dose-dependent neutralizing antibody titers in both younger and older adults, a recent study by researchers from the U.S. and Germany has shown that BNT162b2 is associated with less systemic reactogenicity in elderly individuals – supporting its selection for further phase 2/3 clinical trials. The study is currently available on medRxiv* preprint server.

23 Aug 2020

Raccoon dogs potential intermediate host for SARS-CoV-2

Researchers at the Friedrich Loeffler Institute in Germany have conducted a study demonstrating that raccoon dogs were a potential intermediate host in the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

23 Aug 2020

Developing more precise, targeted therapy for a highly aggressive breast cancer

Taking advantage of a cancer cell's altered metabolism that drives its runaway growth, Princess Margaret researchers are zeroing in on these molecular changes to help them develop more precise drug targets for one of the most deadly breast cancers.

21 Aug 2020

Genomic analysis reveals vulnerability of many animal species to SARS-CoV-2 infection

Humans are not the only species facing a potential threat from SARS-CoV-2, the novel coronavirus that causes COVID-19, according to a new study from the University of California, Davis.

21 Aug 2020

Nasal vaccine effective in preventing COVID-19 infection in mice

Scientists at Washington University School of Medicine in St. Louis have developed a vaccine that targets the SARS-CoV-2 virus, can be given in one dose via the nose and is effective in preventing infection in mice susceptible to the novel coronavirus.

21 Aug 2020

New bioluminescent reporter developed to track DNA double stranded break repair

A new bioluminescent reporter that tracks DNA double stranded break repair in cells has been developed by researchers from Massachusetts General Hospital and the Academia Sinica in Taiwan.

21 Aug 2020

Researchers find clues to successful immune response in the T cells of COVID-19 patients

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

21 Aug 2020

New injectable drug could offer long-lasting protection from HIV with fewer side effects

Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects.

21 Aug 2020

A new mechanism by which microtubule networks instruct neuronal polarity revealed

Prof. MENG Wenxiang's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences recently reported a new mechanism by which microtubule networks instruct neuronal polarity.

21 Aug 2020

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

21 Aug 2020

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

A recent study by researchers at the Sanford Burnham Prebys Medical Discovery Institute and the University of California San Francisco and published on the preprint server bioRxiv in August 2020 shows that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host.

21 Aug 2020

The Native Antigen Company announces custom contract service to develop influenza A and B antigens

The Native Antigen Company, one of the world’s leading suppliers of reagents that enables research into vaccines and diagnostics for emerging and endemic infectious diseases, today announced the introduction of its custom contract service to rapidly develop antigen panels for influenza A and B viruses.

21 Aug 2020

Protein C News and Research

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Bio-Helix announces approved patent for ECL

Study reveals a promising method for treating multiple sclerosis

Study examines the effects of cancer and its treatment on aging process

Study: Fewer types of fungi in the lungs are associated with increased severity of disease in ARDS patients

FDA issues emergency use authorization for convalescent plasma in COVID-19

Loss of supporting cells in olfactory epithelium causes loss of smell in COVID-19

Equine antibody preparation shows greater capacity to neutralize SARS-CoV-2 isolate than human convalescent plasma

Pfizer/BioNTech COVID-19 vaccine candidate BNT162b2 profiled for large scale clinical trials

Raccoon dogs potential intermediate host for SARS-CoV-2

Developing more precise, targeted therapy for a highly aggressive breast cancer

Genomic analysis reveals vulnerability of many animal species to SARS-CoV-2 infection

Nasal vaccine effective in preventing COVID-19 infection in mice

New bioluminescent reporter developed to track DNA double stranded break repair

Researchers find clues to successful immune response in the T cells of COVID-19 patients

New injectable drug could offer long-lasting protection from HIV with fewer side effects

A new mechanism by which microtubule networks instruct neuronal polarity revealed

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

The Native Antigen Company announces custom contract service to develop influenza A and B antigens

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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