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RT after surgery could reduce chances of local DCIS recurrence by 50%

Radiotherapy treatment (RT) after surgery for ductal carcinoma in situ (DCIS) still has a major protective effect against recurrence more than 15 years later, according to the results of an international trial.

23 Mar 2012

House vote on IPAB repeal scheduled for today

The full House is scheduled to vote today on legislation that would repeal the health law's Independent Payment Advisory Board. Some supporters have been frustrated by the measure's link to medical tort reforms, which drove some Democrats, who initially favored rejection of the panel, to oppose the overall bill.

23 Mar 2012

Scientists artificially derive brain stem cells from connective tissue of mice

These stem cells can reproduce and be converted into various types of brain cells. To date, only reprogramming in brain cells that were already fully developed or which had only a limited ability to divide was possible. The new reprogramming method presented by the Bonn scientists and submitted for publication in July 2011 now enables derivation of brain stem cells that are still immature and able to undergo practically unlimited division to be extracted from conventional body cells.

23 Mar 2012

Blocking PFKFB4 enzyme could prevent growth of prostate cancer cells

Cancer Research UK scientists have discovered how blocking a key enzyme, which helps convert glucose into energy, could provide a new way to kill prostate cancer cells, according to a study published in the journal Cancer Discovery.

23 Mar 2012

HCC patients have reduced risk of waitlist mortality

New research shows increasing disparity in mortality among candidates with and without hepatocellular carcinoma (HCC) who are on the waiting list for liver transplantation. The study available in the April issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, found that liver cancer patients are less likely to die on the wait list than non-HCC candidates, prompting transplantation specialists to suggest a reevaluation of current allotment criteria for those with HCC.

23 Mar 2012

U.N.-backed campaign aims to vaccinate 111M children in 20 countries against polio over 4 days

"Some 111.1 million children below the age of five are to be vaccinated against polio in a synchronized campaign covering 20 countries in West and Central Africa starting on Friday," the WHO and UNICEF said in a joint statement on Wednesday, PANA reports.

23 Mar 2012

UI receives three grants to hasten discovery of new TB therapeutics

Forty-five years. That's how long it's been since the last drug - rifampin - hit the market to treat tuberculosis, an infection that affects nearly one third of the world's population and causes 1.8 million deaths annually. The University of Illinois at Chicago College of Pharmacy has received three new federally-funded grants to hasten the discovery of new therapeutic treatments.

23 Mar 2012

tAI could predict sensitivity to chemotherapy in patients with triple-negative breast cancer

Scientists have uncovered a marker of DNA damage that could predict who will respond to platinum-based chemotherapy drugs like cisplatin or carboplatin.

23 Mar 2012

Study provides important clue in type 1 diabetes

In type 1 diabetes (T1D), pancreatic beta cells die from a misguided autoimmune attack, but how and why that happens is still unclear. Now, JDRF-funded scientists from the Indiana University School of Medicine have found that a specific type of cellular stress takes place in pancreatic beta cells before the onset of T1D, and that this stress response in the beta cell may in fact help ignite the autoimmune attack.

23 Mar 2012

PFKFB4 gene leads to excessive growth of prostate cancer cells

Cancer cell metabolism may present a new target for therapy as scientists have uncovered a possible gene that leads to greater growth of prostate cancer cells.

23 Mar 2012

Viewpoints: Health law's threat to individual liberty; Conflicting opinions on the constitutionality of the individual mandate

On Monday, the Supreme Court will begin an extraordinary three-day hearing on the constitutionality of ObamaCare. At stake are the Constitution's structural guarantees of individual liberty, which limit governmental power and ensure political accountability by dividing that power between federal and state authorities. Upholding ObamaCare would destroy this dual-sovereignty system, the most distinctive feature of American constitutionalism.

23 Mar 2012

Verapamil drug may reverse diabetes-related death of pancreatic beta cells

A common high-blood-pressure medication appears to reverse the diabetes-related death of pancreatic beta cells, according to a University of Alabama at Birmingham study published today in the journal Diabetes.

23 Mar 2012

WCI technique uses MRS to detect oncometabolites

Researchers at Winship Cancer Institute have developed a technique for detecting an "oncometabolite", a chemical produced by some brain tumors' warped metabolism, via non-invasive imaging.

23 Mar 2012

USAID Administrator Shah addresses agency's FY13 budget proposal at House Foreign Affairs Committee hearing

Speaking Tuesday at a House Foreign Affairs Committee hearing, USAID Administrator Rajiv Shah said USAID's FY 2013 budget proposal "is slightly lower than last year," but that "future U.S. foreign aid investments will be more 'prioritized, focused and concentrated,'" and he "promised that U.S. aid will still be able to meet global development challenges," VOA's "Breaking News" blog reports.

23 Mar 2012

Physicians preferred over online sources for information by parents of pediatric cancer patients

Parents and adult caregivers of pediatric cancer patients prefer personal consultations with trusted health care providers over online sources for information about their child's illness, according to a University at Buffalo research study.

22 Mar 2012

Sinai coordinator chosen as one of 50 Social Work Heroes for Justice

Carine Chen-McLaughlin, coordinator of Case Management Operations at Sinai Hospital of Baltimore, has been selected as one of 50 Social Work Heroes for Justice by the University of Maryland School of Social Work.

22 Mar 2012

Towards a more comprehensive view of brain-hand relationship

Research at Arizona State University and Columbia University to better understand the intricate sensory and cognitive connections between the brain and the hands has won support from the National Science Foundation. New discoveries about such connections could benefit people with neurological disorders such as Parkinson's disease and cerebral palsy, and those who need prosthetic hands.

22 Mar 2012

Biobanks should set rules for overall process of recognizing IFs and IRRs

Bioethicists at the Johns Hopkins Berman Institute of Bioethics are co-authors on a consensus article placing "significant responsibility" on biobanks to report individual research results (IRRs) and incidental findings (IFs) to the contributors of genetic material.

22 Mar 2012

A rare forum on stem cell biology, engineering and clinical translation

On March 23, during the 41st Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 36th Annual Meeting of the Canadian Association for Dental Research, a symposium titled "TMJ: Stem Cell Biology and Engineering toward Clinical Translation" will provide a rare forum for multidisciplinary discussion of the biology, engineering and clinical translation of fundamental discoveries towards novel clinical therapy.

22 Mar 2012

Reading Arabic is more challenging to the brain

Readers whose mother tongue is Arabic have more challenges reading in Arabic than native Hebrew or English speakers have reading their native languages, because the two halves of the brain divide the labor differently when the brain processes Arabic than when it processes Hebrew or English.

22 Mar 2012

Research News and Research

RT after surgery could reduce chances of local DCIS recurrence by 50%

House vote on IPAB repeal scheduled for today

Scientists artificially derive brain stem cells from connective tissue of mice

Blocking PFKFB4 enzyme could prevent growth of prostate cancer cells

HCC patients have reduced risk of waitlist mortality

U.N.-backed campaign aims to vaccinate 111M children in 20 countries against polio over 4 days

UI receives three grants to hasten discovery of new TB therapeutics

tAI could predict sensitivity to chemotherapy in patients with triple-negative breast cancer

Study provides important clue in type 1 diabetes

PFKFB4 gene leads to excessive growth of prostate cancer cells

Viewpoints: Health law's threat to individual liberty; Conflicting opinions on the constitutionality of the individual mandate

Verapamil drug may reverse diabetes-related death of pancreatic beta cells

WCI technique uses MRS to detect oncometabolites

USAID Administrator Shah addresses agency's FY13 budget proposal at House Foreign Affairs Committee hearing

Physicians preferred over online sources for information by parents of pediatric cancer patients

Sinai coordinator chosen as one of 50 Social Work Heroes for Justice

Towards a more comprehensive view of brain-hand relationship

Biobanks should set rules for overall process of recognizing IFs and IRRs

A rare forum on stem cell biology, engineering and clinical translation

Reading Arabic is more challenging to the brain

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