Efficacy News and Research

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Scientists reveal how Epstein-Barr virus reactivation triggers MIS-C in children

Scientists reveal that reactivation of Epstein-Barr virus (EBV), driven by TGFβ-induced immune suppression, is a key driver of multisystem inflammatory syndrome in children (MIS-C) following COVID-19. Blocking TGFβ may offer a potential new treatment for this life-threatening condition.

13 Mar 2025

Promising drug enhances motor recovery after spinal cord injury

Spinal cord injury (SCI)-a condition that leads to partial or complete paralysis-has a profound impact on millions of individuals globally.

13 Mar 2025

Researchers develop new compound to treat alopecia areata

A research group, led by Dr. Pavel Majer from IOCB Prague, in collaboration with the laboratories of Barbara Slusher and Louis Garza at Johns Hopkins University, have developed a compound that could potentially treat the autoimmune disorder alopecia areata, which causes hair loss leading to the formation of bald patches.

13 Mar 2025

How is academic achievement linked to wellbeing?

This comprehensive study explores the connection between anxiety, cognitive function, and academic success, advocating for holistic educational strategies.

13 Mar 2025

ViiV Healthcare’s investigational broadly neutralising antibody - N6LS - successfully maintains viral suppression in long-acting treatment of HIV

ViiV Healthcare, the global specialist HIV company majority owned by GSK, with Pfizer and Shionogi as shareholders, today announced positive findings from the company’s EMBRACE phase IIb study.

13 Mar 2025

Study reveals an integrated care model for improving outcomes among people who inject drugs

Researchers from the HIV Prevention Trials Network (HPTN) presented results from the HPTN 094 ("INTEGRA") study at the 2025 Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco.

12 Mar 2025

New tissue engineering strategies for spinal cord injury repair

A recent study published in the journal Engineering delves into the application of tissue engineering in spinal cord injury (SCI) repair, presenting a comprehensive review of the latest research and potential treatment strategies.

12 Mar 2025

New treatment option for advanced thymic carcinoma shows promise

Thymic epithelial tumors are a rare group of malignancies originating in the thymus gland, that includes thymoma and thymic carcinoma.

12 Mar 2025

Tecovirimat monotherapy found ineffective for treating clade II mpox in NIH-sponsored trial

NIH-sponsored trial data offer further evidence to help inform mpox treatment decisions.

12 Mar 2025

Targeted alpha therapy offers new hope for treating metastatic melanoma

Metastatic melanoma, also known as stage IV melanoma, is a type of skin cancer that spreads to other parts of the body.

12 Mar 2025

Updates on influenza vaccine strain recommended by WHO (2025-2026 northern hemisphere)

To maintain vaccine efficacy, WHO regularly updates influenza vaccine strains based on global epidemiological, virological, and serological analyses.

From Sino Biological Inc. 12 Mar 2025

Gaps in HPV cancer screening and prevention identified for people living with HIV

A new study published in The Lancet HIV reveals gaps in knowledge surrounding the prevention of HPV-related cancers in people living with HIV and outlines future research priorities.

12 Mar 2025

Aqua aerobics proven to aid weight loss in obese adults

Water/aqua aerobics for 10 or more weeks at a time can trim waist size and aid weight loss, finds a pooled data analysis of the available evidence, published in the open access journal BMJ Open.

12 Mar 2025

Tirzepatide helps people without diabetes lose 13% body weight in real-world study

A real-world study of over 4,000 US patients without type 2 diabetes found that those who persisted with Tirzepatide for at least six months lost an average of 12.9% of their body weight. The study highlights Tirzepatide’s potential as an effective off-label obesity treatment before its formal FDA approval for weight loss.

11 Mar 2025

Automated insulin delivery systems are safe and effective for older adults with type 1 diabetes

New research from Washington State University in collaboration with five other institutions suggests that automated insulin delivery (AID) systems are safe and effective for use by older adults with type 1 diabetes.

11 Mar 2025

Machine learning models fall short in predicting in-hospital mortality

It would be greatly beneficial to physicians trying to save lives in intensive care units if they could be alerted when a patient's condition rapidly deteriorates or shows vitals in highly abnormal ranges.

11 Mar 2025

Gender gaps in peripheral vascular disease impact diagnosis and treatment

The disparities between men and women in prevalence, risk factors and symptoms of peripheral vascular disease (PVD) have a profound impact on prevention, diagnosis, treatment and outcomes for women, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

11 Mar 2025

New automated system revolutionizes drug evaluation in zebrafish

Preclinical drug evaluation, especially for cardiotoxicity, is a critical stage in the drug development process.

11 Mar 2025

Novel regulators in digestive tract disease progression and treatment

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive tract diseases, positioning these molecules as potential biomarkers for diagnosis, prognosis, and targeted therapies. The comprehensive review explores the biogenesis, classification, and biological functions of tsRNAs, shedding light on their influence over cellular processes such as translation regulation, epigenetic modification, and protein interactions.

11 Mar 2025

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.

11 Mar 2025

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Efficacy News and Research

Scientists reveal how Epstein-Barr virus reactivation triggers MIS-C in children

Promising drug enhances motor recovery after spinal cord injury

Researchers develop new compound to treat alopecia areata

How is academic achievement linked to wellbeing?

ViiV Healthcare’s investigational broadly neutralising antibody - N6LS - successfully maintains viral suppression in long-acting treatment of HIV

Study reveals an integrated care model for improving outcomes among people who inject drugs

New tissue engineering strategies for spinal cord injury repair

New treatment option for advanced thymic carcinoma shows promise

Tecovirimat monotherapy found ineffective for treating clade II mpox in NIH-sponsored trial

Targeted alpha therapy offers new hope for treating metastatic melanoma

Updates on influenza vaccine strain recommended by WHO (2025-2026 northern hemisphere)

Gaps in HPV cancer screening and prevention identified for people living with HIV

Aqua aerobics proven to aid weight loss in obese adults

Tirzepatide helps people without diabetes lose 13% body weight in real-world study

Automated insulin delivery systems are safe and effective for older adults with type 1 diabetes

Machine learning models fall short in predicting in-hospital mortality

Gender gaps in peripheral vascular disease impact diagnosis and treatment

New automated system revolutionizes drug evaluation in zebrafish

Novel regulators in digestive tract disease progression and treatment

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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