Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Study discloses vital role of LINC00901 and its regulatory network in pancreatic cancer progression

Chemical modifications of RNA molecules, such as m6A, can critically impact gene expression, influencing various aspects of cancer development and progression.

4 Aug 2023

Gene expression ratio linked to prognosis in solid tumors

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, engaged by multiple cell types in the tumor microenvironment, that control human cancers.

3 Aug 2023

Dopamine neurons may play a bigger role in motor control than previously thought

Dopamine: It's not just for rewards anymore. In a new Northwestern University-led study, researchers identified and recorded from three genetic subtypes of dopamine neurons in the midbrain region of a mouse model.

3 Aug 2023

Nanoengineered bioink improves tumor model accuracy

Scientists from the Terasaki Institute for Biomedical Innovation have developed a nanoengineered bioink with improved bonding and cross-linking capabilities for 3D bioprinting of tumor models.

3 Aug 2023

Children raised in rural areas have better regulated immune systems

Children raised in rural environments who spend a lot of time outdoors with some exposure to animals grow to have better regulated immune systems than children living in urban environments, a new study has found.

3 Aug 2023

The mechanisms of triptan using metabolomics and transcriptomics in spontaneous migraine attacks

Researchers discuss the mechanisms of triptans for the treatment of spontaneous migraine attacks by using transcriptomics and metabolomics.

3 Aug 2023

UCLA study finds new way to protect livers during transplantation

UCLA-led research describes the role that a protein called CEACAM1 plays in protecting the liver from injury during the transplantation process, potentially improving transplant outcomes.

2 Aug 2023

TTUHSC researcher receives $1.76 million grant to investigate new pancreatic cancer treatment

With a survival rate in the single digits, pancreatic ductal adenocarcinoma (PDAC) is highly lethal. In fact, by the time PDAC is clinically diagnosed, it is already considered incurable via surgery or other means in up to 90% of patients.

2 Aug 2023

The impact of medicinal plants on the gut microbiome in cancer

Researchers evaluate the associations between medicinal plants, the gut microbiome, and cancer.

2 Aug 2023

Antiviral protein protects against COVID-19 in live mouse models

A mammalian protein previously shown by UT Southwestern microbiologists to inhibit the virus that causes COVID-19 in cell culture also protected live mouse models, significantly limiting infection in the lung cells and diminishing the symptoms.

1 Aug 2023

ICI therapy linked to unique immune response in arthritis

Immune checkpoint inhibitor (ICI) therapies used to treat cancer come with the risk of adverse autoimmune responses, including arthritis that can persist for years and require joint replacement surgery.

1 Aug 2023

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, today published a new study explaining how they took a protein once thought to be too challenging for targeted therapy, proliferating cell nuclear antigen (PCNA), and developed a targeted chemotherapy that appears to annihilate all solid tumors in preclinical research.

1 Aug 2023

The effects of oxidative stress on women’s fertility

Scientists review existing literature to assess the relationship between oxidative stress and female infertility.

1 Aug 2023

Investigating the neurological effects of SARS-CoV-2: anosmia and neuroinvasion as separate phenomena

A group of researchers investigated the neurotropic potential of SARS-CoV-2 and its variants by studying their ability to invade the brain through the olfactory pathway in hamsters.

1 Aug 2023