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Discovery offers promising alternative to current therapies for AMD and ROP

A research team led by scientists at Beth Israel Deaconess Medical Center and the University of New Mexico School of Medicine has identified a small molecule that treats animal models of aged macular degeneration (AMD) and retinopathy of prematurity (ROP) by preventing the overgrowth of blood vessels that are characteristic of these two retinal diseases.

3 Nov 2015

Rotation model provides explanation of ligand activation mechanism of dimeric receptors

"This 'rotation model', which made the cover of BioEssays, represents a true paradigm shift in the membrane receptor field," stated Prof. Pierre De Meyts, a renowned researcher of insulin and receptor binding for almost half a century and one of the reviewers of the paper by Prof. Ichiro Maruyama, the head of the Information Processing Biology Unit at Okinawa Institute of Science and Technology Graduate University.

31 Oct 2015

New TSRI study highlights urgent need for new treatments to fight growing cancer metastases

A new study from scientists at The Scripps Research Institute helps explain why cancer metastasis is so hard to stop.

29 Oct 2015

Breastfeeding associated with lower risk of developing hormone-receptor negative breast cancer

A large international study shows that breastfeeding is associated with a lower risk of developing an aggressive form of breast cancer called hormone-receptor negative. This new combined evidence shows the risk was reduced by up to 20% in women who breastfed.

29 Oct 2015

Research provides novel insight into potential new therapeutic targets for triple-negative breast cancer

Recent laboratory findings provide novel insight into potential new therapeutic approaches for triple-negative breast cancer, a particularly difficult to treat and aggressive form of the disease.

28 Oct 2015

Lower doses of chemicals found in personal care products may contribute to breast cancer risk

Estrogen-mimicking chemicals called parabens, which are commonly found in an array of personal care products, may be more dangerous at lower doses than previously thought, according to a new study.

27 Oct 2015

Early trial results in lung cancer

Results from early phase trials investigating different therapeutic agents in lung cancer patients were presented during the third Presidential Session at the European Cancer Congress in Vienna, Austria. Here we summarise two studies reported at the session.

22 Oct 2015

CV risk assessment essential for CML TKI trial design

The risk and impact of cardiovascular adverse events in long-term users of tyrosine kinase inhibitors for chronic myeloid leukaemia is highlighted in a review published in the Journal of Clinical Oncology.

22 Oct 2015

New study from TSRI and Salk points to cause of debilitating nerve disease

Scientists at The Scripps Research Institute (TSRI) and the Salk Institute for Biological Studies have discovered how a mutant protein triggers nerve damage in a subtype of Charcot-Marie-Tooth (CMT) diseases, a group of currently untreatable conditions that cause loss of function in a person’s hands and feet.

22 Oct 2015

Cancer-causing parasitic worm may help patients recover from wounds, say JCU scientists

It's short, ugly and deadly. But James Cook University scientists have found a cancer-causing, parasitic worm could help patients recover from their wounds.

22 Oct 2015

Low levels of stem cell factor associated with increased risk of cardiovascular disease

New research indicates that low levels of a growth factor called stem cell factor (SCF)--which is thought to be important for blood vessel repair--are linked with an increased risk of cardiovascular disease.

20 Oct 2015

NAM announces election of three new members from UC San Diego School of Medicine

The National Academy of Medicine announced today the election of three new members from University of California, San Diego School of Medicine: Napoleone Ferrara, MD; Christopher K. Glass, MD, PhD; and Roberto Malinow, MD, PhD. Election to NAM is considered among the highest honors in the fields of health and medicine.

20 Oct 2015

TSRI researchers find way to change leukemia cells into leukemia-killing immune cells

Scientists at The Scripps Research Institute have found a way to change leukemia cells into leukemia-killing immune cells. The surprise finding could lead to a powerful new therapy for leukemia and possibly other cancers.

20 Oct 2015

Diabetic retinopathy therapy innovations: an interview with Richard Kirk, CEO of Polyphotonix

In the UK there are currently over 3.5 million people who have diabetes, with a growth rate exceeding 280,000 people per year. Diabetic retinopathy is the most common complication of diabetes.

19 Oct 2015

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

Neural stem cells transplanted into damaged brain sites in mice dramatically improved both motor and cognitive impairments associated with dementia with Lewy bodies, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

19 Oct 2015

EKF’s PointMan™ used in cancer biopsy research

EKF, announces results from a study involving EKF Molecular’s PointMan™ DNA enrichment technology have been published in Clinical Cancer Research.

From EKF Diagnostics 15 Oct 2015

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

An international research team led by scientists at the University of New Mexico Cancer Center discovered and developed a novel ligand peptide-mimic that inhibits abnormal overgrowth of blood vessels in retinal diseases and tumors. The discovery could lead to new drugs that keep cancers from growing. The team published a paper in the journal Science Translational Medicine.

15 Oct 2015

VTT examines effectiveness of beauty patch using unique imaging technology

VTT Technical Research Centre of Finland has analysed the effectiveness of its beauty patch, using a technique for imaging live tissue to demonstrate the patch's beneficial effects on the skin. Preliminary results show that already after two weeks usage the patch together with cosmetic serum adds collagen, which helps skin tissue to stay supple.

14 Oct 2015

Research: Epigenetic factor reduces sensitivity of breast cancer cells to common cancer drug

A surprising, paradoxical relationship between a tumor suppressor molecule and an oncogene may be the key to explaining and working around how breast cancer tumor cells become desensitized to a common cancer drug, found researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Oct 2015

Minority women with subtypes of breast cancer less likely to receive recommended treatment regimens

Main Finding(s): Minority women were more likely to have aggressive subtypes of breast cancer and were more likely to receive non-guideline concordant treatment when compared with non-Hispanic white women.

13 Oct 2015

Growth Factor News and Research

Discovery offers promising alternative to current therapies for AMD and ROP

Rotation model provides explanation of ligand activation mechanism of dimeric receptors

New TSRI study highlights urgent need for new treatments to fight growing cancer metastases

Breastfeeding associated with lower risk of developing hormone-receptor negative breast cancer

Research provides novel insight into potential new therapeutic targets for triple-negative breast cancer

Lower doses of chemicals found in personal care products may contribute to breast cancer risk

Early trial results in lung cancer

CV risk assessment essential for CML TKI trial design

New study from TSRI and Salk points to cause of debilitating nerve disease

Cancer-causing parasitic worm may help patients recover from wounds, say JCU scientists

Low levels of stem cell factor associated with increased risk of cardiovascular disease

NAM announces election of three new members from UC San Diego School of Medicine

TSRI researchers find way to change leukemia cells into leukemia-killing immune cells

Diabetic retinopathy therapy innovations: an interview with Richard Kirk, CEO of Polyphotonix

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

EKF’s PointMan™ used in cancer biopsy research

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

VTT examines effectiveness of beauty patch using unique imaging technology

Research: Epigenetic factor reduces sensitivity of breast cancer cells to common cancer drug

Minority women with subtypes of breast cancer less likely to receive recommended treatment regimens

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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