Proliferation News and Research

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Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Oncotarget published "Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma" which reported that Multiple Myeloma patients suffer disease relapse due to the development of therapeutic resistance. Increasing evidence suggests that immunotherapeutic strategies can provide durable responses.

29 Sep 2021

Researchers create an integrated pipeline for performing genetic screening studies

Today's genetic engineers have a plethora of resources at their disposal: an ever-increasing number of massive datasets available online, highly precise gene editing tools like CRISPR, and cheap gene sequencing methods. But the proliferation of new technologies has not come with a clear roadmap to help researchers figure out which genes to target, which tools to use, and how to interpret their results. So, a team of scientists and engineers at Harvard's Wyss Institute for Biologically Inspired Engineering, Harvard Medical School (HMS), and the MIT Media Lab decided to make one.

28 Sep 2021

Scientists discover novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia

A new type of targeting chaperon protein HSP70 inhibitor QL47 was recently discovered by a team led by Prof. LIU Qingsong from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences to treat FLT3-ITD-positive acute myeloid leukemia (AML).

27 Sep 2021

Researchers discover potential Achilles heel of pediatric acute myeloid leukemia

Researchers at Baylor College of Medicine and Texas Children's Hospital have uncovered a potential Achilles heel of acute myeloid leukemia (AML) in children that could lead to new treatments for this devastating disease.

23 Sep 2021

Researchers use new laser-assisted technology for bioprinting adult neuron cells

A group of researchers including a Concordia PhD student have developed a new method of bioprinting adult neuron cells. They're using a new laser-assisted technology that maintains high levels of cell viability and functionality.

22 Sep 2021

Pinning down Pin1: Potential COVID-19 therapy

In a recent study scientists have demonstrated that Pin1 is one of the key cellular molecules necessary for SARS-CoV-2 propagation.

22 Sep 2021

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

Careful pipetting reduces the stress on cells in culture

Cell viability, defined as the proportion of live cells in a sample, is a fundamental consideration in all cell culture techniques.

From INTEGRA Biosciences 21 Sep 2021

Research could lead to new treatment option for breast cancer patients with brain metastases

Breast cancer patients whose cancer spreads to the brain may soon have new treatment options, thanks to research led by CU Cancer Center member Diana Cittelly, PhD.

21 Sep 2021

Study uncovers a new way to counter immune suppression in tumors

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

20 Sep 2021

New discovery elucidates the link between inflammation and pancreatic cancer development

A new discovery from researchers at The University of Texas MD Anderson Cancer Center has clarified the long-established connection between inflammation and pancreatic cancer development.

16 Sep 2021

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Gliomas are the most common primary brain tumors in adults. Among them, high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them. The disease rapidly progresses to an advanced stage in a short span of time, and the survival of such patients is often dismal.

16 Sep 2021

Researchers identify key factor responsible for brain development during evolution

As humans, we have a large and intricately folded neocortex that accounts for many of our intellectual abilities and sets us apart from all other species

16 Sep 2021

Blood serum test can identify which breast cancer patients have slow-growing disease

Researchers with the SWOG Cancer Research Network have found that patients with metastatic hormone receptor-positive breast cancer who have low activity levels of the enzyme sTK1 in their blood serum at the start of anti-estrogen treatment live longer and go longer without their disease progressing than patients with high levels.

14 Sep 2021

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

A recent study examined the ability of SARS-CoV-2 to impact DNA damage response and telomere stability in Vero E6 cells.

13 Sep 2021

Functional impairment of HIV-specific T cells precedes aborted virus control

HIV is a master of evading the immune system, using a variety of methods to prevent the body from being able to find and kill it.

13 Sep 2021

Results from Phase 0/1 trial of ribociclib plus everolimus in patients with high-grade glioma announced

The Ivy Brain Tumor Center at Barrow Neurological Institute, the largest early-phase drug development program for brain cancer in the world, announced results from their Phase 0/1 clinical trial of ribociclib plus everolimus in patients with high-grade glioma (HGG).

13 Sep 2021

Cryopreservation Excipient for Cell Therapies

AMSBIO has launched STEM-CELLBANKER® EX - a next generation cryopreservation product that eliminates the need for the traditional washing steps required in cell therapy product development.

From AMS Biotechnology 10 Sep 2021

Molecular underpinning of chronic bone infection in patients with mycobacterial disease revealed

About a quarter of the world's population is infected with tuberculosis bacteria, according to the World Health Organization, but only about 5 to 10% of those infected will develop symptoms. These pathogens are mycobacteria, which are everywhere, including in chlorine-treated tap water.

8 Sep 2021

Researchers find potential new target for treating systemic inflammation in obesity

A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity.

7 Sep 2021

Proliferation News and Research

Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Researchers create an integrated pipeline for performing genetic screening studies

Scientists discover novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia

Researchers discover potential Achilles heel of pediatric acute myeloid leukemia

Researchers use new laser-assisted technology for bioprinting adult neuron cells

Pinning down Pin1: Potential COVID-19 therapy

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Careful pipetting reduces the stress on cells in culture

Research could lead to new treatment option for breast cancer patients with brain metastases

Study uncovers a new way to counter immune suppression in tumors

New discovery elucidates the link between inflammation and pancreatic cancer development

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Researchers identify key factor responsible for brain development during evolution

Blood serum test can identify which breast cancer patients have slow-growing disease

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

Functional impairment of HIV-specific T cells precedes aborted virus control

Results from Phase 0/1 trial of ribociclib plus everolimus in patients with high-grade glioma announced

Cryopreservation Excipient for Cell Therapies

Molecular underpinning of chronic bone infection in patients with mycobacterial disease revealed

Researchers find potential new target for treating systemic inflammation in obesity

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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