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Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis."

9 Feb 2024

AI tool maps protein function in tumors, paving way for personalized cancer treatment

Scientists have developed a new AI tool that maps the function of proteins in a cancerous tumor, enabling clinicians to decide how to target treatment in a more precise way.

9 Feb 2024

CARB-X awards $1.8 million to Visby Medical to develop a portable rapid PCR test for gonorrhea

Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award up to US$1.8 million to biotechnology company, Visby Medical, to develop a portable rapid polymerase chain reaction (PCR) diagnostic to detect the presence of the pathogen that causes gonorrhea, Neisseria gonorrhoeae (NG), and its susceptibility to ciprofloxacin, a former frontline oral antibiotic that can no longer treat resistant NG.

9 Feb 2024

Machine learning tool reads brain scans for early signs of psychosis

The onset of psychosis can be predicted before it occurs, using a machine-learning tool which can classify MRI brain scans into those who are healthy and those at risk of a psychotic episode.

8 Feb 2024

ANU discovery provides new insight into how the immune system fights malaria

Researchers from The Australian National University (ANU) have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria.

8 Feb 2024

Mitochondrial misfire sparks inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA - a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy.

8 Feb 2024

Study discovers a direct connection between the brain and its surrounding environment

In a recent study of the brain's waste drainage system, researchers from Washington University in St. Louis, collaborating with investigators at the National Institute of Neurological Disorders and Stroke (NINDS), a part of the National Institute of Health (NIH), discovered a direct connection between the brain and its tough protective covering, the dura mater.

8 Feb 2024

New treatment target found for CDKL5 deficiency disorder

Scientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy.

7 Feb 2024

New review: 1.6% of women and girls have debilitating Premenstrual Dysphoric Disorder

Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Disorder (PMDD), according to a new review of global studies.

7 Feb 2024

World-first discovery offers potential cure for lupus

Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment.

6 Feb 2024

Fluorescent sensor array accurately detects multiple amyloids in biological samples

Many neurodegenerative diseases, including Alzheimer's and Parkinson's, are difficult to diagnose before symptoms begin to appear.

5 Feb 2024

Clinical trials becoming more inclusive across race and ethnicity, new data shows

Clinical trials and medical research have been historically lacking in diversity among all groups.

5 Feb 2024

New inhibitor drug shows promise in preventing diabetic eye and kidney disease

New research has shown a new type of inhibitor drug could prevent microvascular diabetic complications, such as diabetic eye and kidney disease.

2 Feb 2024

$Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery$

Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery

A large multicenter clinical trial co-led by University of Maryland School of Medicine researchers large multicenter clinical trial co-led by University of Maryland School of Medicine researchers found that an antiseptic containing iodine resulted in about one-quarter fewer post-surgical infections in patients with limb fractures compared to another frequently used skin antiseptic.

2 Feb 2024

IU surgeon-scientist investigates the role of sinus microbiome in chronic rhinosinusitis

An Indiana University School of Medicine surgeon-scientist is leading a multi-institutional grant investigating the role of the sinus microbiome in chronic rhinosinusitis, an inflammatory disease that causes the lining of the sinuses to swell.

1 Feb 2024

CRISPR revolutionized: New method edits genes directly in the body

Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.

1 Feb 2024

The anti-cancer potential of sRNAs isolated from different mushroom species

Study reveals that sRNAs from certain mushrooms, particularly Boletus edulis and Agaricus bisporus, show promising anti-cancer properties, with varying efficacy across different species.

31 Jan 2024

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

A researcher at the University of Houston College of Pharmacy Drug Discovery Institute is working to revolutionize treatment regimens for triple-negative breast cancer (TNBC) by proving that nebivolol, an FDA-approved drug for high blood pressure, is effective in treating it.

31 Jan 2024

Mechanically ventilated patients in intermediate care units of rural hospitals have higher death rates

A new National Institutes of Health-supported study finds that patients receiving ventilator life support in the intermediate care units – a potentially less costly alternative for people not sick enough for the intensive care units (ICUs) but too ill for the general ward – of rural hospitals had significantly higher death rates than patients in the same type of unit at urban hospitals.

31 Jan 2024

AI-based applications for personalized cancer medicine and related regulatory challenges: An overview

Personalized therapies could improve the treatment of many diseases in the future. Cancer medicine in particular has made significant progress in recent years.

31 Jan 2024

Medical Research News and Research

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

AI tool maps protein function in tumors, paving way for personalized cancer treatment

CARB-X awards $1.8 million to Visby Medical to develop a portable rapid PCR test for gonorrhea

Machine learning tool reads brain scans for early signs of psychosis

ANU discovery provides new insight into how the immune system fights malaria

Mitochondrial misfire sparks inflammation

Study discovers a direct connection between the brain and its surrounding environment

New treatment target found for CDKL5 deficiency disorder

New review: 1.6% of women and girls have debilitating Premenstrual Dysphoric Disorder

World-first discovery offers potential cure for lupus

Fluorescent sensor array accurately detects multiple amyloids in biological samples

Clinical trials becoming more inclusive across race and ethnicity, new data shows

New inhibitor drug shows promise in preventing diabetic eye and kidney disease

Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery

IU surgeon-scientist investigates the role of sinus microbiome in chronic rhinosinusitis

CRISPR revolutionized: New method edits genes directly in the body

The anti-cancer potential of sRNAs isolated from different mushroom species

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

Mechanically ventilated patients in intermediate care units of rural hospitals have higher death rates

AI-based applications for personalized cancer medicine and related regulatory challenges: An overview

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