Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

New findings about nerve pathways to brown fat could lead to obesity treatments

A UCLA-led team of researchers has found nerve pathways that supply brown adipose tissue (BAT), a type of tissue that releases chemical energy from fat metabolism as heat – a finding that could pave the way toward using it to treat obesity and related metabolic conditions.

5 Oct 2023

Blood test for pan-cancer biomarker could revolutionize early cancer detection

Diagnostic tools for timely, accurate and inexpensive early cancer detection that can assess risk or monitor response to treatment could help patients get the care they need faster and improve existing care strategies.

5 Oct 2023

New AI model predicts therapeutic targets for age-related diseases

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 18, entitled, "Biomedical generative pre-trained based transformer language model for age-related disease target discovery."

4 Oct 2023

Genetics may influence a person’s ability to adhere to a vegetarian diet

From Impossible Burger to "Meatless Mondays," going meat-free is certainly in vogue. But a person's genetic makeup plays a role in determining whether they can stick to a strict vegetarian diet, a new Northwestern Medicine study has found.

4 Oct 2023

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Researchers investigated endotype-phenotype associations in atopic dermatitis (AD) beyond its general clinical severity.

4 Oct 2023

Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).

3 Oct 2023

Cancer pathway process can be streamlined with the adoption of AI and automation

Medicine is a constantly evolving science where small changes can have a huge impact on the lives of patients. When it comes to a cancer diagnosis and treatment, every minute counts. According to European Commission estimates, the cancer incidence by 2040 will impact just over three million people a year.

30 Sep 2023

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

A new tau PET radiotracer, 18F-SNFT-1, has been found to be more effective than existing tau PET radiotracers in identifying Alzheimer's disease in its earliest stages, according to research published in the September issue of The Journal of Nuclear Medicine.

29 Sep 2023

Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.

29 Sep 2023

Challenges and opportunities for better lung cancer care for the elderly

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, "Promising trends in lung cancer care, but are we overlooking the majority?"

28 Sep 2023

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

28 Sep 2023

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

In some patients, infection with the pandemic virus SARS-CoV-2 can trigger a dangerous immune response in hardened fatty deposits (plaques) lining the heart's largest blood vessels, a new study shows.

28 Sep 2023

Hospitalized COVID patients displayed multiple organ abnormalities five months after infection

A study looking at the longer-term impact of COVID-19 has found that nearly a third of patients displayed abnormalities in multiple organs five months after infection, some of which have been shown through previous work to be evidence of tissue damage.

28 Sep 2023

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

SARS-CoV-2, the virus that causes COVID-19, can directly infect the arteries of the heart and cause the fatty plaque inside arteries to become highly inflamed, increasing the risk of heart attack and stroke, according to a study funded by the National Institutes of Health.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage.

28 Sep 2023

Blocking Notch signaling pathway could reverse age-related bone loss

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.

27 Sep 2023

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

A new imaging agent, 68Ga-ABY-025, can predict early metabolic response to human epidermal growth factor receptor 2 (HER2)-targeted treatment in HER2-positive metastatic breast cancer patients, according to new research published in the September issue of The Journal of Nuclear Medicine.

27 Sep 2023

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

Researchers utilize imaging findings to elucidate how Alzheimer's dementia can present considerable variations depending on the sex of the individual.

27 Sep 2023

Pathology News and Research

Further Reading

New findings about nerve pathways to brown fat could lead to obesity treatments

Blood test for pan-cancer biomarker could revolutionize early cancer detection

New AI model predicts therapeutic targets for age-related diseases

Genetics may influence a person’s ability to adhere to a vegetarian diet

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Microglial states and their impact on Alzheimer's disease

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Cancer pathway process can be streamlined with the adoption of AI and automation

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

Challenges and opportunities for better lung cancer care for the elderly

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

Hospitalized COVID patients displayed multiple organ abnormalities five months after infection

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Examining the cardiac pathology in fatal cases of yellow fever

Blocking Notch signaling pathway could reverse age-related bone loss

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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