Aortic Stenosis News and Research

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RDAVR system improves survival of patients with severe aortic stenosis

When replacing a defective aortic valve with a new one, restoring function is the first priority. However, variables such as durability, length of surgery, duration of heart stoppage, size of the surgical incision, postoperative pain, and complications are other important considerations.

17 May 2016

Moderate sedation leads to better clinical outcomes than general anesthesia for TAVR patients

A new study finds the use of moderate sedation, in which patients do not need a breathing tube, leads to better clinical outcomes as compared to general anesthesia for patients undergoing transcatheter aortic valve replacement (TAVR).

9 May 2016

TAVR procedure could provide improved health outcomes for inoperable patients

A novel procedure for heart valve replacement surgery could provide improved health outcomes for patients who cannot have open heart surgery, as well as being a cost effective alternative.

22 Apr 2016

LivaNova announces first implant of Perceval sutureless valve in PERSIST-AVR trial

LivaNova, PLC, a global medical technology company, announced today the first implant of the Perceval sutureless valve in the PERSIST-AVR trial at CHU Brabois, University of Lorraine, Nancy, France.

7 Apr 2016

Study evaluates long-term outcomes of TAVR with SAPIEN 3 in intermediate-risk patients

To account for baseline differences, TAVR patients were compared by a propensity score analysis with patients randomized to receive surgical intervention in a precursor study, PARTNER 2A. Propensity scoring analysis is a statistical technique used to reduce bias from potential confounding variables, which in this case was used to identify surgical patients from a previous study who would be comparable to TAVR patients in this study.

4 Apr 2016

Frequent TAVR to replace damaged aortic heart valve improves patient outcomes

The more frequently a hospital performs a minimally invasive technique called transcatheter aortic valve replacement, or TAVR, to replace a damaged aortic heart valve, the better patients fare, on average, immediately after the procedure, researchers reported at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Edwards Lifesciences' SAPIEN 3 transcatheter heart valve approved in Japan

Edwards Lifesciences Corporation, the global leader in patient-focused innovations for structural heart disease and critical care monitoring, today announced that the Japanese Ministry of Health, Labor and Welfare approved the Edwards SAPIEN 3 transcatheter heart valve for the treatment of patients suffering from severe, symptomatic aortic stenosis.

16 Mar 2016

Edwards Lifesciences' net sales grow 1.3% to $615.5 million in third quarter 2015

Edwards Lifesciences Corporation, the global leader in the science of heart valves and hemodynamic monitoring, today reported financial results for the quarter ended September 30, 2015.

27 Oct 2015

Sorin Group initiates PERSIST-AVR trial to evaluate Perceval sutureless aortic valve against standard sutured bioprostheses

Sorin Group, a global medical device company and a leader in the treatment of cardiovascular diseases, today announced the initiation of PERSIST-AVR, the first international, prospective, post-market randomized multi-center trial evaluating the Perceval sutureless aortic valve compared to standard sutured bioprostheses in patients with aortic valve disease.

7 Oct 2015

Anti-coagulant medications quickly resolve blood clots that could impair valve motion

Heart valve replacements made from tissue (bioprosthetic valves) have long been thought to be spared the complication of blood clot formation. Researchers have now found that about 15 percent of all bioprosthetic aortic heart valve patients develop blood clots on the leaflets affecting valve opening, regardless of whether the patient received the new valve via open-heart surgery or a minimally-invasive catheter procedure, a new study from the Cedars-Sinai Heart Institute shows.

6 Oct 2015

Training session can improve cardiologists’ ability to detect basic and advanced murmurs

Cardiologists failed to identify more than half of basic and about 35 percent of advanced pre-recorded murmurs, but skills improved after a 90 minute training session, according to research presented today at the European Society of Cardiology Congress 2015.

1 Sep 2015

Elderly patients can benefit from new, minimally invasive surgery for aortic valve replacement

Select patients age 90 years and older with aortic stenosis (AS) can benefit from a relatively new, minimally invasive surgery for aortic valve replacement, according to an article in the September 2015 issue of The Annals of Thoracic Surgery.

1 Sep 2015

PCR London Valves 2015 to focus on innovative transcatheter therapies for valvular heart disease

For the first time in its 6-year history, PCR London Valves, the world's largest Course solely devoted to addressing the rapidly expanding and innovative field of transcatheter therapies for valvular heart disease, will be taking place in Berlin, Germany, from the 20 to 22 of September 2015.

29 Aug 2015

Loyola implants new percutaneous aortic heart valve that does not require open surgery

Loyola University Medical Center is the first center in Illinois to implant a new percutaneous aortic heart valve that does not require open heart surgery.

19 Aug 2015

Orlando Health Heart Institute first in Central Florida to use CoreValve Evolut R System to replace heart valves

Leading edge heart valve technology is helping improve patient outcomes and giving doctors greater accuracy when implanting replacement valves. Interventional cardiologists and cardiovascular surgeons at the Orlando Health Heart Institute are the first in Central Florida to use the newly approved recapturable, self-expanding CoreValve Evolut R System.

12 Aug 2015

Edwards Lifesciences announces FDA approval of SAPIEN 3 transcatheter aortic heart valve

Edwards Lifesciences Corporation, the global leader in the science of heart valves and hemodynamic monitoring, today announced U.S. Food and Drug Administration approval of its most advanced transcatheter aortic heart valve – the Edwards SAPIEN 3 valve with the Commander Delivery System – for the treatment of high-risk patients suffering from severe, symptomatic aortic stenosis.

18 Jun 2015

Two-year data show continued survival advantage for self-expanding TAVR

Two-year data show a continued survival advantage for self-expanding transcatheter aortic valve replacement (TAVR) over standard surgery in high-risk patients with severe aortic stenosis, according to research presented at the American College of Cardiology's 64th Annual Scientific Session.

20 Mar 2015

Minimally invasive surgery helps elderly patients with severe aortic stenosis live longer

Elderly patients once considered too frail or too sick for aortic valve replacement surgery are living longer, with better quality of life, following a minimally invasive surgery, compared to patients who did not undergo surgery, according a study published in The Lancet today.

16 Mar 2015

New study explores patient outcomes one year after TAVR procedure

In an analysis of outcomes of about 12,000 patients who underwent transcatheter aortic valve replacement, death rate after one year was nearly one in four; of those alive at 12 months, almost half had not been rehospitalized and approximately 25 percent had only one hospitalization, according to a study in the March 10 issue of JAMA.

12 Mar 2015

Aortic valve replacement is safe to treat severe aortic stenosis in very eldery patients

Aortic valve replacement (AVR) can safely be used to treat severe aortic stenosis in patients age 90 years and older and is associated with a low risk of operative stroke and mortality, according to a study in the November 2014 issue of The Annals of Thoracic Surgery.

30 Oct 2014