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EGCG effect: Study suggests green tea compound may ease inflammatory iron deficiency

Whether a polyphenol found in green tea, reduces inflammation.

3 Jan 2024

Understanding acylspermidines' secrets could lead to treatments for various diseases

In a significant advancement in the field of biochemistry, scientists at the Boyce Thompson Institute (BTI) and Cornell University have uncovered new insights into a family of metabolites, acylspermidines, that could change how we understand aging and fight diseases.

2 Jan 2024

Scientists take a major step towards realizing synthetic CO2 fixing pathways in living cells

Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2).

2 Jan 2024

New research highlights potential of cytisine for global smoking cessation efforts

A new study published in Addiction has found that cytisine, a low-cost, generic stop-smoking aid that has been used in eastern Europe since the 1960s, increases the chances of successful smoking cessation by more than two-fold compared with placebo and may be more effective than nicotine replacement therapy. It has a benign safety profile, with no evidence of serious safety concerns.

2 Jan 2024

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2/3 for the treatment of tissue-agnostic solid tumors bringing the total number of PCCs nominated in 2023 to six.

28 Dec 2023

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at the first COVID-19 symptoms, due to the weakening of innate antiviral immunity, leading to delayed viral clearance and adverse outcomes in severe viral pneumonias.

28 Dec 2023

Degron Therapeutics announced as winner of AFCR's 2023 BRACE Award Venture Competition

The Asian Fund for Cancer Research (AFCR) is pleased to announce that Degron Therapeutics was selected as the winner of the 2023 BRACE Award Venture Competition.

27 Dec 2023

New drug screening system helps uncover promising target for pancreatic cancer treatments

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine.

26 Dec 2023

Fox urine compound effectively repels flies through multisensory activation

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

25 Dec 2023

Study sheds light on enzyme's role in advanced prostate cancer progression

Prostate cancer is the most common cancer in men other than skin cancer, and more than 288,000 new cases are diagnosed every year, according to the American Cancer Society.

21 Dec 2023

Brazilian researchers create cutting-edge nanoparticle weapon against tuberculosis

A low-cost technology involving nanoparticles loaded with antibiotics and other antimicrobial compounds that can be used in multiple attacks on infections by the bacterium responsible for most cases of tuberculosis has been developed by researchers at São Paulo State University (UNESP) in Brazil and is reported in an article published in the journal Carbohydrate Polymers.

20 Dec 2023

First new antibiotic class in decades discovered using explainable AI platform

Scientists have discovered one of the first new classes of antibiotics identified in the past 60 years, and the first discovered leveraging an AI-powered platform built around explainable deep learning.

20 Dec 2023

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

A Nature journal study employs deep learning to analyze chemical sub-structures, leading to the discovery of new structural classes of antibiotics, showcasing the potential of AI in accelerating antibiotic development.

20 Dec 2023

Scientists design non-hallucinogenic psychedelic treatments potentially accelerating research on mental health benefits

Researchers identified 5-hydroxytryptamine 2A (5-HT2A) receptor (5-HT2AR) signaling pathways associated with psychedelic potential.

19 Dec 2023

Festive food and health benefits: Newcastle University experts examine Christmas dinner staples

In less than a week's time, families around the country will be sitting down to tuck into their traditional Christmas dinner.

18 Dec 2023

Leaky gut linked to depressive disorders: New insights into microbiota-induced epigenetic changes

A study in the journal Genes highlights how a leaky gut can lead to depressive disorders through changes in gut microbiota-derived metabolites, emphasizing the role of diet, environmental factors, and probiotics in managing these conditions.

18 Dec 2023

Scientists crack the code for targeting cancer's 'death star' protein

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS.

18 Dec 2023

Hemoglobin-like protein plays an important role in the development of the heart, study finds

In a landmark study led by the University of Maryland School of Medicine, researchers discovered for the first time that a certain kind of protein similar to hemoglobin, called cytoglobin, plays an important role in the development of the heart.

15 Dec 2023

New methodology may be important in the fight against antimicrobial resistance

NTNU has developed a promising antibiotic candidate against MRSA. Behind the discovery lies a methodology that may be important in the fight against antimicrobial resistance.

15 Dec 2023

New study unpacks the hidden power of breastfeeding

Breastfeeding, even partially alongside formula feeding, changes the chemical makeup-;or metabolome-;of an infant's gut in ways that positively influence brain development and may boost test scores years later, suggests new CU Boulder research.

13 Dec 2023

Compound News and Research

EGCG effect: Study suggests green tea compound may ease inflammatory iron deficiency

Understanding acylspermidines' secrets could lead to treatments for various diseases

Scientists take a major step towards realizing synthetic CO2 fixing pathways in living cells

New research highlights potential of cytisine for global smoking cessation efforts

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Degron Therapeutics announced as winner of AFCR's 2023 BRACE Award Venture Competition

New drug screening system helps uncover promising target for pancreatic cancer treatments

Fox urine compound effectively repels flies through multisensory activation

Study sheds light on enzyme's role in advanced prostate cancer progression

Brazilian researchers create cutting-edge nanoparticle weapon against tuberculosis

First new antibiotic class in decades discovered using explainable AI platform

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

Scientists design non-hallucinogenic psychedelic treatments potentially accelerating research on mental health benefits

Festive food and health benefits: Newcastle University experts examine Christmas dinner staples

Leaky gut linked to depressive disorders: New insights into microbiota-induced epigenetic changes

Scientists crack the code for targeting cancer's 'death star' protein

Hemoglobin-like protein plays an important role in the development of the heart, study finds

New methodology may be important in the fight against antimicrobial resistance

New study unpacks the hidden power of breastfeeding

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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