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Study finds benefits of personalized ventilation in ICU care

A seven-year international, multi-centre clinical trial led by London Health Sciences Centre Research Institute (LHSCRI) and St. Michael's Hospital, a site of Unity Health Toronto, has found that a new ventilation mode called proportional assist ventilation (PAV+™) could improve outcomes for patients in the intensive care unit (ICU) who require help breathing.

24 Jul 2025

Low treatment completion rates hinder recovery for teens with cannabis use disorder

Cannabis use disorder in adolescents in the United States remains a growing threat despite declines in cannabis use.

22 Jul 2025

Cleaner air after industrial plant closure improves lung health in local residents

A new study by NYU Langone Health researchers found that the shutdown of a significant fossil fuel pollution source near Pittsburgh, PA, resulted in immediate improvements in respiratory health.

22 Jul 2025

New biomarker ELL2 identified for early diagnosis and prognosis in sepsis

Sepsis is a life-threatening condition caused by organ dysfunction resulting from the body's dysregulated response to infection.

18 Jul 2025

PAR1 protein found to boost lung fluid drainage during injury

A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the lungs are injured according to researchers from Weill Cornell Medicine.

18 Jul 2025

Uncovering a protective RNA molecule in kidney stress and disease

Cells contain helper molecules called transfer RNAs (tRNAs), which carry building blocks (amino acids) to make proteins.

17 Jul 2025

Children from deprived areas face worse outcomes in intensive care

Children from ethnic minority backgrounds and those living in areas with higher levels of child poverty were more likely to die in intensive care than White children and those from the least deprived areas.

11 Jul 2025

HonorHealth study shows major breakthrough in treating structural shock

An 8-year HonorHealth Research Institute clinical trial, using non-surgical techniques, showed 86% of patients with a type of usually fatal low blood pressure known as 'structural shock' survived at least 3 months, while 73% survived at least 6 months, according to a study presented here at a major heart convention.

27 Jun 2025

Methylene blue emerges as an adjunct in septic shock

Recent evidence suggests methylene blue may help reduce vasopressor needs and ICU stays in septic shock, but current data do not support replacing standard therapies. Further research is needed to clarify its optimal dosing, timing, and patient selection for best outcomes.

26 Jun 2025

Global report calls for innovation and cooperation to improve newborn health

More effective platforms for drug and medical device development and better cross sector engagement are urgently required to prevent the 'unacceptably high' newborn death rate, according to a global report.

26 Jun 2025

FDA-approved drug may help restore breathing in obesity-related sleep disorder

Researchers from the George Washington University have uncovered promising evidence in an animal study that shows setmelanotide, an FDA-approved medication for a rare genetic obesity disorder, may offer a pathway for treating a life-threatening form of sleep-disordered breathing called Obesity Hypoventilation Syndrome.

17 Jun 2025

Digital inhalers show promise in predicting COPD flare-ups

Digital inhalers may help predict impending acute exacerbations of chronic obstructive pulmonary disease (COPD), according to a new study.

17 Jun 2025

Study illustrates a powerful and efficient approach for comparing different standard treatments

A clinical trial led by researchers at The Ottawa Hospital and the University of Ottawa and published in the New England Journal of Medicine illustrates a powerful and efficient approach for comparing different standard treatments.

13 Jun 2025

Post-Intensive Care Syndrome patients experience long-term deficits in cognitive and physical function

More than half of ICU survivors may experience Post-Intensive Care Syndrome (PICS), which involves new or worsening physical, psychological, or cognitive impairments after a critical illness.

20 May 2025

Rising temperatures drive global surge in obstructive sleep apnea severity

Rising temperatures increase the severity of obstructive sleep apnea (OSA), according to a large new study published at the ATS 2025 International Conference.

18 May 2025

Palliative care for cardiovascular conditions may help relieve symptoms and improve quality of life

Palliative care may help relieve symptoms and improve quality of life for people with cardiovascular disease and ensure that treatment is aligned with the patient's personal beliefs and values throughout all stages of illness, whether they are hospitalized in a cardiac intensive care unit or receiving outpatient care, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

15 May 2025

Lung function decline in COPD patients accelerated by mucus plug persistence

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States, most often caused by cigarette smoking or long-term exposure to air pollutants.

14 May 2025

HIV uses circular RNAs to evade immunity and boost replication

In a groundbreaking discovery, researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body's natural defenses and use it to support its survival and replication.

13 May 2025

New heart rate measure offers clues to future cognitive health

Healthy hearts are adaptable, and heartbeats exhibit complex variation as they adjust to tiny changes in the body and environment.

7 May 2025

Study: One in four early cardiogenic shock patients experience worse outcomes

In one of the largest studies of early cardiogenic shock (CS) patients, where blood flow is still functioning to vital organs, researchers demonstrated that 26% experienced worse outcomes, including care escalation, CS deterioration, or in-hospital mortality.

2 May 2025