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New cryogenic mass spectrometry approach reveals inner structure of lipid nanoparticles

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues.

23 May 2025

Advancing GPCR drug discovery with fragment screening using GCI technology

Evotec's insights into GPCRs and waveRAPID technology reveal new opportunities in drug discovery, focusing on orphan receptors and innovative screening methods.

From Creoptix (A Malvern Panalytical brand) 23 May 2025

Discovery reveals how neuronal ion channels store molecular memory

Researchers have discovered how an ion channel in the brain's neurons has a kind of 'molecular memory', which contributes to the formation and preservation of lifelong memories.

19 May 2025

What makes H5N1 a pandemic risk and how can we stop it?

A new PEARLS article in PLoS Pathogens reviews the rapid evolution and pandemic potential of emerging influenza A viruses, with a focus on H5N1. It highlights scientific advances and future strategies to outpace the virus, from next-generation vaccines to AI-driven antiviral discovery.

19 May 2025

New micropipette allows precise ion delivery to individual brain cells

Researchers at Linköping University have developed a new type of pipette that can deliver ions to individual neurons without affecting the sensitive extracellular milieu.

7 May 2025

Understanding the particle drifting effect with Dr. Na Li

Join Dr. Na Li as she explores the mysteries of the particle drifting effect and its practical applications in real-world scenarios.

From Pion Inc 5 May 2025

Advancing benzodiazepine detection for toxicology

Learn how experts are advancing benzodiazepine analysis and detection using insights from the lab.

From Waters Advanced Diagnostics 5 May 2025

A journey through science, software, and innovation: Insights from the Bruker software team

Follow Bruker's experts as they discuss the SCRUM approach to software development in the scientific industry.

From Bruker Daltonics 29 Apr 2025

Metrion Biosciences launches NaV1.9 high-throughput screening assay to strengthen screening portfolio and advance research on new medicines for pain

Metrion Biosciences ("Metrion"), the specialist preclinical contract research organization (CRO) and a global leader in ion channel services, today announced the launch of its validated, high-throughput NaV1.9 screening assay to advance discovery and development of novel pain therapeutics.

28 Apr 2025

Obesity changes how the gut responds to plant compounds, researchers report

Researchers found that the impact of polyphenols rutin and genistein on the human fecal metabolome varies significantly by body mass index (BMI). Lower BMI individuals showed more diverse metabolic responses, revealing how gut health and obesity could shape polyphenol metabolism.

28 Apr 2025

NIH study reveals how inflammation affects pain perception

Researchers uncover the cellular and molecular basis for sensing heat and inflammatory pain.

24 Apr 2025

Step-and-shoot proton arc therapy reduces cancer treatment side effects

For many cancer patients, side effects from radiation can be debilitating. But a new way of delivering radiation treatment has proven effective at eliminating a hard-to-treat cancer with the only side effect being light skin discoloration, even nine months after treatment.

24 Apr 2025

Study examines how COX-2 regulates ferroptosis in chronic liver injury

Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. +

18 Apr 2025

Low vitamin D levels damage erectile health via superoxide surge, study finds

Vitamin D deficiency directly causes erectile dysfunction by increasing superoxide and reducing protective SLPI levels, as shown in human tissue and animal models. This breakthrough reveals why low vitamin D may lead to poor sexual health and resistance to standard ED treatments.

15 Apr 2025

New insights into how myasthenia gravis antibodies disrupt muscle function

People who suffer from the autoimmune disease myasthenia gravis experience muscle weakness that can affect any of the muscles we use to blink, smile or even move our body around.

9 Apr 2025

Study uncovers conserved development and evolutionary innovations in the human hypothalamus

In a new study published in Developmental Cell on April 8, a research team led by Prof. WU Qingfeng at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has demonstrated the conserved cellular development and evolutionary innovations in the developing human hypothalamus.

9 Apr 2025