Lung Disease News and Research

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Early clinical events predict disease progression in very early systemic sclerosis

The VEDOSS project has previously shown that 70% of patients with Raynaud's phenomenon and at least one red flag – systemic sclerosis (SSc)-specific antibodies, puffy fingers, or an SSc pattern on nailfold capillaroscopy –will fulfil the 2013 ACR/EULAR SSc criteria within 5 years.

13 Jun 2025

Breakthrough drug delivery system transports genetic therapies directly to the lungs

Scientists have made a key breakthrough for treating respiratory diseases by developing a new drug delivery system that transports genetic therapies directly to the lungs, opening promising possibilities for patients with conditions like lung cancer and cystic fibrosis.

5 Jun 2025

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

Researchers report that rentosertib, an AI-discovered TNIK inhibitor, showed promising safety and potential to improve lung function in patients with idiopathic pulmonary fibrosis in a 12-week phase 2a clinical trial. The highest dose group demonstrated a trend toward increased forced vital capacity, especially among patients not receiving standard antifibrotic therapy, supporting further clinical investigation.

4 Jun 2025

Feds chop enforcement staff and halt rules meant to curb black lung in coal miners

In early April, President Donald Trump gathered dozens of hard-hat-clad coal miners around him in the White House East Room.

29 May 2025

Maestro John Mauceri returns to the stage in renewed health

John Mauceri, an award-winning music conductor, author, and recording artist, is celebrating his return to the stage in better health following specialized cardiac surgery at NYU Langone Health to treat a rare and life-threatening heart condition.

27 May 2025

Researchers discover a genetic link to long COVID

An international team of researchers has found a genetic link to long-term symptoms after COVID-19.

21 May 2025

Air pollution exposure in pregnancy may increase asthma risk for the next generation

A mother's exposure to air pollution during pregnancy can increase asthma risk in her adult offspring, according to a new mouse study published at the ATS 2025 International Conference.

20 May 2025

Inhaled microplastics suppress pulmonary macrophages critical to the immune system

Microplastics are ubiquitous in the environment, and we all routinely inhale these tiny pollutants. Now new research published at the ATS 2025 International Conference has found that inhaled microplastics suppress pulmonary macrophages, a type of white blood cell found in the lungs that are critical to the immune system.

19 May 2025

Repeated antibiotics in preterm infants linked to long-term lung problems

Repeated perinatal antibiotic exposure in very low-birth-weight preterm infants was associated with impaired lung function and a higher risk of asthma at early school age. The findings underscore the need for cautious antibiotic use and targeted respiratory health strategies in this high-risk group.

18 May 2025

US hospitals see rising complications in patients with takotsubo cardiomyopathy

A large US study found that takotsubo cardiomyopathy is associated with high in-hospital mortality and serious cardiovascular complications, with no improvements in outcomes over five years. Mortality is more than double in men compared to women, and risk factors include age, race, and hospital characteristics.

15 May 2025

Study sheds light on public attitudes about transplant allocations

Becoming an organ donor has never been easier. Registration is available online when renewing a driver's license or, for iPhone users, through an app.

15 May 2025

Trump’s fast-tracked deal for a copper mine heightens existential fight for Apache

Carrying eagle feathers and chanting prayers, Western Apache runners hit the road on a roughly 80-mile journey this month to try to save their sacred land from being fast-tracked by President Donald Trump into a copper mine.

14 May 2025

KL-6 levels help differentiate interstitial lung disease from abnormalities

Krebs von den Lungen-6 (KL-6), predominantly expressed by type II alveolar cells, is linked to the prognosis and severity of interstitial lung disease (ILD).

10 May 2025

Nirsevimab slashes RSV hospitalizations in infants by 78% in real-world study

A Spanish study found that nirsevimab prophylaxis significantly reduced infant hospitalizations, ICU admissions, and severe symptoms linked to RSV and other respiratory viruses. Hospitalizations for RSV dropped by 78% following nirsevimab rollout in Madrid maternity wards.

8 May 2025

Study uncovers how co-infection by two bacteria suppresses immune response

The incidence of infection by Mycobacterium abscessus, is increasing in patients with cystic fibrosis, chronic obstructive pulmonary disease (COPD), and other chronic pulmonary diseases, leading to an accelerated lung function decline.

8 May 2025

Comprehensive treatment approach helps patients manage rheumatoid arthritis

Although rheumatoid arthritis is an autoimmune disease with no cure, a tailored, multidisciplinary treatment approach at Cedars-Sinai's Inflammatory Arthritis Clinical Center helps patients get back to the activities they enjoy.

7 May 2025

Wearable X-ray technology makes respiratory scans more comfortable for young children

Light conversion technology developed by University of Queensland researchers will be used for wearable X-ray devices that make respiratory scans more comfortable for young children.

6 May 2025

UVA findings hold promise for developing targeted treatments for Long COVID lung complications

Groundbreaking research from the University of Virginia School of Medicine has revealed crucial new insights into the immune systems of COVID-19 survivors, particularly those struggling with persistent breathing issues.

5 May 2025

Virtual pulmonary rehabilitation proves to be safe and effective for COPD patients

Virtual pulmonary rehabilitation is a safe, effective alternative to traditional pulmonary rehabilitation programs for people with chronic obstructive pulmonary disease (COPD) who also require supplemental oxygen, according to a new report.

1 May 2025

Brensocatib once-daily pill shows benefits for chronic lung disease

Results of a large, global clinical trial spanning five continents with over 1,700 patients with bronchiectasis, published this April in the New England Journal of Medicine, demonstrated benefits of an investigational, once-a-day pill called brensocatib as a therapy for the chronic lung condition.

30 Apr 2025