Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Advancements in organoids could transform treatment of spinal cord injury and peripheral nerve injury

A recent review published in Engineering explores the construction and potential applications of spinal cord and peripheral nerve organoids for regenerative medicine in neurotrauma.

24 Oct 2025

New York Regional Diabetes Research Center established with $10.8 million NIH grant

Albert Einstein College of Medicine has received a five-year, $10.8 million grant from the National Institutes of Health (NIH) to create the New York Regional Diabetes Research Center (NYR-DRC), a newly expanded multi-institutional center co-led with the Icahn School of Medicine at Mount Sinai and Weill Cornell Medicine.

23 Oct 2025

The future of automation: Machine learning–driven hepatocyte and organoid counting

DeNovix discusses how customer demand inspired the development of specialized CellDrop applications for hepatocytes and organoids.

From DeNovix Inc. 22 Oct 2025

HCS-3DX platform enables large-scale, high-precision screening of cellular models

The HCS-3DX platform performs automated analysis of three-dimensional cell cultures, known as spheroids.

21 Oct 2025

New AI-driven approach identifies treatments to reprogram and destroy cancer stem cells

Scientists at University of California San Diego have developed a new approach to destroying cancer stem cells – hard-to-find cells that help cancers spread, come back after treatment and resist therapy.

21 Oct 2025

Exploring the link between leaky blood-brain barrier and major depressive disorder

Women are affected by severe depression twice as often as men. The reasons for this have not yet been fully clarified.

16 Oct 2025

Ancient lead exposure may have shaped human evolution and language

A groundbreaking international study changes the view that exposure to the toxic metal lead is largely a post-industrial phenomenon.

15 Oct 2025

Microarray platform could help predict immune‐mediated drug‐induced liver injury

Researchers at Cincinnati Children's Hospital Medical Center in collaboration with Roche, have developed a next-generation human liver organoid microarray platform that could help predict which drugs may cause harmful immune reactions in some people.

14 Oct 2025

Study shows c-Kit–expressing sweet cells are central to taste bud regeneration after nerve injury

Taste is one of our most vital senses, shaping appetite, nutrition, and quality of life. Yet taste buds are fragile, relying heavily on the nerves that connect them to the brain.

6 Oct 2025

New research reveals the cervix as a truly immunocompetent tissue

Cervical epithelial cells are far from passive bystanders in the body's immune system. New research shows they actually play an active and highly coordinated role in detecting and fighting infections. That's the conclusion of an international research team led by Associate Professor Cindrilla Chumduri from Aarhus University, and now published in the journal Science Advances.

6 Oct 2025

Stem cells and organoids offer a new understanding of APOL1 kidney disease

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental factors, as well as existing medical conditions. Known genetic risk factors for CKD include mutations in a gene called APOL1.

3 Oct 2025

Small molecule AVJ16 shows promise in targeting lung cancer growth

Researchers have discovered a promising new approach to lung cancer treatment. A small molecule called AVJ16 selectively blocks the cancer-driving protein IGF2BP1, halting tumor growth in preclinical studies and killing cancer cells in patient-derived models—while leaving healthy cells unharmed.

29 Sep 2025

New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies

Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers like lung and prostate cancer.

26 Sep 2025

Patient-derived organoids advance cancer therapy and vaccines

Tiny, three-dimensional organoid models are reshaping cancer research by recreating the intricate architecture and diversity of human tumors.

25 Sep 2025

AstroCapsules offer a new way to reduce brain inflammation

Neuroinflammation is linked to a host of detrimental brain disorders, including Alzheimer's and Parkinson's disease.

25 Sep 2025

Lab-grown mini brains reveal neural misfires linked to schizophrenia and bipolar disorder

Pea-sized brains grown in a lab have for the first time revealed the unique way neurons might misfire due to schizophrenia and bipolar disorder, psychiatric ailments that affect millions of people worldwide but are difficult to diagnose because of the lack of understanding of their molecular basis.

22 Sep 2025

Scientists unveil new obesity drug that reprograms fat and energy use

Details of a new drug that aims to treat the underlying causes of obesity are being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September).

18 Sep 2025

Breakthrough in building functional synthetic kidneys using assembloids

A USC Stem Cell-led research team has achieved a major step forward in the effort to build mouse and human synthetic kidneys.

17 Sep 2025

ISSCR expresses concern over NIH decision on fetal tissue research funding

The International Society for Stem Cell Research (ISSCR), the largest professional organization of stem cell researchers from around the world, is concerned about a recent statement attributed to NIH that the agency will not renew research grants involving human fetal tissue (HFT), and that research with HFT is not conducted responsibly or transparently.

13 Sep 2025

Weill Cornell Medicine receives $3.4 million NIH grant to study type 1 diabetes development

Weill Cornell Medicine has received a four-year, $3.4 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, for a study of the details and dynamics of the autoimmune process that causes type 1 diabetes.

11 Sep 2025

Organoids News and Research

Further Reading

Advancements in organoids could transform treatment of spinal cord injury and peripheral nerve injury

New York Regional Diabetes Research Center established with $10.8 million NIH grant

The future of automation: Machine learning–driven hepatocyte and organoid counting

HCS-3DX platform enables large-scale, high-precision screening of cellular models

New AI-driven approach identifies treatments to reprogram and destroy cancer stem cells

Exploring the link between leaky blood-brain barrier and major depressive disorder

Ancient lead exposure may have shaped human evolution and language

Microarray platform could help predict immune‐mediated drug‐induced liver injury

Study shows c-Kit–expressing sweet cells are central to taste bud regeneration after nerve injury

New research reveals the cervix as a truly immunocompetent tissue

Stem cells and organoids offer a new understanding of APOL1 kidney disease

Small molecule AVJ16 shows promise in targeting lung cancer growth

New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies

Patient-derived organoids advance cancer therapy and vaccines

AstroCapsules offer a new way to reduce brain inflammation

Lab-grown mini brains reveal neural misfires linked to schizophrenia and bipolar disorder

Scientists unveil new obesity drug that reprograms fat and energy use

Breakthrough in building functional synthetic kidneys using assembloids

ISSCR expresses concern over NIH decision on fetal tissue research funding

Weill Cornell Medicine receives $3.4 million NIH grant to study type 1 diabetes development

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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