Pancreatic Cancer News and Research

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Pancreatic cancer is the fourth leading cause of all cancer deaths in the United States and the third leading cause of cancer deaths in individuals ages 40 to 60. Approximately 37,000 Americans are diagnosed with pancreatic cancer each year, and, each year, approximately the same number die from it. Often, pancreatic cancer is found too late for surgical intervention, and chemotherapy and radiation treatments have little effect.

McGill researchers create AI tool to detect hidden disease markers in single cells

McGill University researchers have developed an artificial intelligence tool that can detect previously invisible disease markers inside single cells.

2 Oct 2025

Novel treatment disrupts tumor immunosuppression in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate below 10%.

26 Sep 2025

Tumor cells adapt and thrive in damaged parts of the pancreas

Pancreatic cancer is one of the most aggressive cancer types. A new study from Karolinska Institutet, in collaboration with the Department of Pathology at Karolinska University Hospital, shows that tumor cells grow not only in the connective tissue-rich environment typical of the disease, but also in damaged parts of the pancreas where normal tissue is altered.

26 Sep 2025

AI model maps lifetime disease risks to transform future healthcare planning

Researchers developed Delphi-2M, a transformer-based AI trained on UK Biobank and Danish health data to predict and simulate lifetime trajectories for 1,256 diseases. It accurately forecasted long-term multimorbidity risks, generated synthetic health records, and highlighted comorbidity patterns while exposing key biases.

18 Sep 2025

Oral microbiome linked to threefold higher pancreatic cancer risk

Twenty-seven species of bacteria and fungi among the hundreds that live in people's mouths have been collectively tied to a 3.5 times greater risk of developing pancreatic cancer, a study led by NYU Langone Health and its Perlmutter Cancer Center shows.

18 Sep 2025

The 15th AACR cancer progress report highlights scientific advances

The American Association for Cancer Research (AACR) released the 15th edition of its annual Cancer Progress Report. A cornerstone of the AACR's educational and advocacy efforts, this comprehensive report provides the latest statistics on cancer incidence, mortality, and survivorship and highlights how federal investments in basic, translational, and clinical cancer research and cancer-related population sciences have led to impressive scientific advances that are improving health and saving lives.

17 Sep 2025

Can high-protein supplements improve cancer recovery?

A systematic review shows high-protein oral nutritional supplements can lower complications and hospital stays in cancer patients, improving recovery outcomes.

16 Sep 2025

New genetic test redefines diagnosis and management of hereditary pancreatitis

A new genetic test developed at Mayo Clinic is redefining how clinicians diagnose and manage hereditary pancreatitis.

11 Sep 2025

NYU Langone strengthens world-leading GI cancer program with renowned leaders

NYU Langone Health's Perlmutter Cancer Center announces the arrival of acclaimed cancer leaders Anirban Maitra, MD, and Manuel Hidalgo, MD, as co-directors of a new Gastrointestinal (GI) Cancer Center.

5 Sep 2025

Smoking fuels pancreatic cancer growth through immune suppression

A new study explains why smokers have a higher chance of developing pancreatic cancer and why they tend to have worse outcomes than nonsmokers.

4 Sep 2025

New advances offer hope in the fight against KRAS-driven pancreatic cancer

Accounting for nearly 90% of all pancreatic cancers, pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of just 13%. Late-stage diagnosis, limited surgical options, and toxic chemotherapy regimens contribute to its poor outcomes.

28 Aug 2025

Multi-analyte test accurately identifies brain cancers using cerebrospinal fluid

A novel, multi-analyte test developed by researchers at the Johns Hopkins Kimmel Cancer Center, its Ludwig Center and the Johns Hopkins Department of Neurosurgery can accurately identify brain cancers using small samples of cerebrospinal fluid (CSF), offering a promising new tool to guide clinical decision-making.

27 Aug 2025

New study uncovers a surprising mechanism of resistance to immunotherapy

A new international study led by researchers at Moffitt Cancer Center, the Karolinska Institutet and the University of Texas MD Anderson Cancer Center has uncovered a surprising mechanism of resistance to immunotherapy: cancer's ability to injure nearby nerves.

21 Aug 2025

New formulation of chemotherapy drug opens doors to advanced cancer treatment options

University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy.

21 Aug 2025

Johns Hopkins team develops a more reliable AI for early cancer detection

Two studies led by Johns Hopkins Kimmel Cancer Center, Ludwig Center, and Johns Hopkins Whiting School of Engineering researchers report on a powerful new method that significantly improves the reliability and accuracy of artificial intelligence (AI) for many applications. As an example, they apply the new method to early cancer detection from blood samples, known as liquid biopsy.

19 Aug 2025

Fucosylation emerges as a key player in digestive inflammatory diseases and cancers

Fucosylation, a crucial post-translational modification, has emerged as a significant factor influencing digestive inflammatory diseases and cancers.

18 Aug 2025

Dementia-like protein clumping found in early pancreatic cancer cells

Cancer Research UK-funded scientists have uncovered dementia-like behaviour in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat disease linked to 6,900 deaths in the UK every year.

17 Aug 2025

NYU Langone Hospital—Suffolk performs first robotic cancer surgeries

Continuing its transformation since joining NYU Langone Health, the operative team at NYU Langone Hospital—Suffolk recently performed four complex robotic surgeries that had never been offered at the facility before, three of which successfully removed cancerous tumors from patients.

13 Aug 2025

Nudibranchs (sea slugs) emerge as a promising source of cancer drugs

Researchers reviewed the antitumor potential of bioactive compounds from nudibranchs, marine mollusks that acquire or synthesize potent chemical defenses. These compounds, often sourced from their diet, show promising cancer-fighting activity through mechanisms like DNA damage, oxidative stress, and apoptosis.

12 Aug 2025